1. (100%) Inhibition of cytosolic glutathione S-transferase activity from rat liver by copper - Letelier, María Eugenia; Martínez, M.; González Lira, Víctor Manuel; Faúndez, Mario; Aracena Parks, Paula
H2O2 inactivation of particular GST isoforms has been reported, with no information regarding the ov ...
- 13-ago-2009

2. (96%) Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein - Jiménez T., Inés; Aracena Stiven, Paula; Letelier, María Eugenia; Navarro, P.; Speisky C., Hernán
Metallothionein (MT) and reduced glutathione (GSH) play an important role in the intracellular handl ...
- 13-ago-2009

3. (90%) Possible mechanisms underlying copper-induced damage in biological membranes leading to cellular toxicity - Letelier, María Eugenia; Lepe, Ana María; Faúndez, Mario; Salazar, Julia; Marín, Rigoberto; Aracena Parks, Paula; Speisky, Hernán
It is generally accepted that copper toxicity is a consequence of the generation of reactive oxygen ...
- 01-ago-2009

4. (90%) Liver microsomal biotransformation of nitro-aryl drugs: Mechanism for potential oxidative stress induction - Letelier, María Eugenia; Izquierdo Lazo, Pamela Alejandra; Godoy Oviedo, Luis; Lepe Agrodnik, Ana María; Faúndez Cáceres, Mario Antonio
Toxic effects of several nitro-aryl drugs are attributed to the nitro-reduction that may be suffered ...
- 13-ago-2009

5. (88%) Copper modifies liver microsomal UDP-glucuronyltransferase activity through different and opposite mechanisms - Letelier, María Eugenia; Lagos, Fernando; Faúndez, Mario; Miranda, Dante; Montoya, Margarita; Aracena Parks, Paula; González Lira, Víctor Manuel
Treatment of hepatic microsomes with Fe3+/ascorbate activates UDP-glucuronyltransferase (UGT), a phe ...
- 12-ago-2009

6. (84%) Antioxidant effects of 1,4-dihydropyridine and nitroso aryl derivatives on the Fe+3/ascorbate-stimulated lipid peroxidation in rat brain slices - Díaz Araya, Guillermo; Godoy Oviedo, Luis; Naranjo, Luis; Squella, J. A.; Letelier, María Eugenia; Núñez Vergara, Luis J.
1. Lipid peroxidation in rat brain slices was induced by Fe+3/ascorbate. 2. Brain lipid peroxidation ...
- 12-ago-2009

7. (78%) Microsomal UDP-glucuronyltransferase in rat liver: Oxidative activation - Letelier, María Eugenia; Pimentel Miranda, Alejandra Patricia; Pino, Paulina; Lepe Agrodnik, Ana María; Faúndez Cáceres, Mario Antonio; Aracena Parks, Paula; Speisky C., Hernán
Activation of microsomal UDP-glucuronyltransferase (UDPGT) activity by treatment of hepatic microsom ...
- 13-ago-2009

8. (72%) Topical anti-inflammatory activity of 2 alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae - Aguirre, M. C.; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Erazo, Silvia; Letelier, María Eugenia; Cassels Niven, Bruce K.; Silva, X.; Alegría, S.; Negrete, Rosa
Leaf extracts of Ugni molinae Turcz. are used in the Chilean cosmetic industry on the assumption tha ...
- 13-ago-2009

9. (60%) Nitroaryl-1,4-dihydropyridines as antioxidants against rat liver microsomes oxidation induced by iron/ascorbate, Nitrofurantoin and naphthalene - Letelier, María Eugenia; Entrala Alrruiz, Paz Andrea; López Alarcón, Camilo Ignacio; González Lira, Víctor Manuel; Molina Berríos, Alfredo; Cortés Troncoso, Juan; Jara Sandoval, José; Santander, P.; Núñez Vergara, Luis J.
1,4-Dihydropyridines (DHPs) used in the treatment of cardiovascular diseases, are calcium channel an ...
- 13-ago-2009