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rss_1.0 Otros recursos de Wehrens, Xander H.T.

Resultados 1 - 10 de 22 de Wehrens, Xander H.T.. (0 segundos)

1. (�) Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs - José A. Herrera; Christopher S. Ward; Meagan R. Pitcher; Alan K. Percy; Steven Skinner; Walter E. Kaufmann; Daniel G. Glaze; Xander H. T. Wehrens; Jeffrey L. Neul
breathing patterns. To explore the role of Na+ channel blockers on QT in people with RTT, we performed
- 24-may-2016

2. (�) The mitochondrial uniporter controls fight or flight heart rate increases - Wu, Yuejin; Rasmussen, Tyler P.; Koval, Olha M.; Joiner, Mei-ling A.; Hall, Duane D.; Chen, Biyi; Luczak, Elizabeth D.; Wang, Qiongling; Rokita, Adam G.; Wehrens, Xander H. T.; Song, Longsheng; Anderson, Mark E.
Heart rate increases are a fundamental adaptation to physiological stress, while inappropriate heart rate increases are resistant to current therapies. However, the metabolic mechanisms driving heart
- 21-jul-2015

3. (�) Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development - Giudice, Jimena; Xia, Zheng; Scavuzzo, Marissa A.; Ward, Amanda J.; Kalsotra, Auinash; Wang, Wei; Wehrens, Xander H. T.; Burge, Christopher B.; Li, Wei; Cooper, Thomas A.; Wang, Eric Tzy-shi
During postnatal development the heart undergoes a rapid and dramatic transition to adult function ...). Here we perform deep RNA-sequencing on RNA from cardiomyocytes and cardiac fibroblasts to conduct
- 01-abr-2015

4. (�) Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides - Ho, Hsiang-Ting; Liu, Bin; Snyder, Jedidiah S.; Lou, Qing; Brundage, Elizabeth A.; Velez-Cortes, Florencia; Wang, Honglan; Ziolo, Mark T.; Anderson, Mark E.; Sen, Chandan K.; Wehrens, Xander H.T.; Fedorov, Vadim V.; Biesiadecki, Brandon J.; Hund, Thomas J.; Györke, Sándor
- 02-ene-2015

5. (�) Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation - Wang, Jun; Bai, Yan; Li, Na; Ye, Wenduo; Zhang, Min; Greene, Stephanie B.; Tao, Ye; Chen, Yiping; Wehrens, Xander H. T.; Martin, James F.
. It is critical to elucidate the molecular mechanisms underlying AF, given that the prevalence of AF is expected to dramatically increase as the human population ages. We identified a microRNA (miR
- 25-dic-2014

6. (�) Calcium dysregulation in atrial fibrillation: the role of CaMKII - Heijman, Jordi; Voigt, Niels; Wehrens, Xander H. T.; Dobrev, Dobromir
make it more difficult to treat. Recent research has suggested an important role for Ca2+-dysregulation ... arrhythmogenic mechanisms contributing to the initiation and maintenance of AF. In addition, AF is self
- 14-mar-2014

7. (�) Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy - Sarma, Satyam; Li, Na; van Oort, Ralph J.; Reynolds, Corey; Skapura, Darlene G.; Wehrens, Xander H. T.
Aberrant intracellular Ca2+ regulation is believed to contribute to the development of ... phosphorylation of RyR2 at S2808 contributes to abnormal Ca2+ homeostasis associated with dystrophic
- 30-jul-2011

8. (�) Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification - Wang, Jun; Klysik, Elzbieta; Sood, Subeena; Johnson, Randy L.; Wehrens, Xander H. T.; Martin, James F.
association studies implicated a region of human chromosome 4q25 in familial AF and AFL, ≈150 kb distal to the Pitx2 homeobox gene, a developmental left–right asymmetry (LRA) gene. To investigate the
- 30-jul-2011

9. (�) Stress synchronizes calcium release and promotes SR calcium leak - Wang, Wei; Wehrens, Xander H T
- 30-jul-2011

10. (�) Animal models of arrhythmogenic cardiomyopathy - McCauley, Mark D.; Wehrens, Xander H. T.
Arrhythmogenic cardiomyopathies are a heterogeneous group of pathological conditions that give rise to myocardial dysfunction with an increased risk for atrial or ventricular arrhythmias. Inherited
- 28-jul-2011

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