Otros recursos de Wehrens, Xander H.T.

Resultados 1 - 5 de 5 de Wehrens, Xander H.T.. (0 segundos)

  1. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. (�)

    Priyatansh Gurha; Tiannan Wang; Ashley H Larimore; Yassine Sassi; Cei Abreu-Goodger; Maricela O Ramirez; Anilkumar K Reddy; Stefan Engelhardt; George E Taffet; Xander H T Wehrens; Mark L Entman; Antony Rodriguez
    transcription and adaptation to hemodynamic stress by pressure overload in mice. Recent evidence also .... We analyzed transgenic mice with enhanced levels of miR-22 expression in adult cardiomyocytes to

  2. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. (�)

    Sayali S Dixit; Tiannan Wang; Eiffel John Q Manzano; Shin Yoo; Jeongkyung Lee; David Y Chiang; Nicole Ryan; Jonathan L Respress; Vijay K Yechoor; Xander H T Wehrens
    Altered insulin secretion contributes to the pathogenesis of type 2 diabetes. This alteration is ... [Ca(2+)]cyt leads to activation of Ca(2+)/calmodulin-dependent protein kinase II (CAMKII), which, in

  3. Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway. (�)

    Dajun Liu; Luping Huang; Yanlin Wang; Wei Wang; Xander H T Wehrens; Tatiana Belousova; Maen Abdelrahim; Gabriel DiMattia; David Sheikh-Hamad
    idiopathic dilated cardiomyopathy. STC1 localizes to the inner mitochondrial membrane and transgenic over ... hypothesis that STC1 uncouples mitochondrial oxidative phosphorylation--to suppress superoxide

  4. Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs (�)

    José A. Herrera; Christopher S. Ward; Meagan R. Pitcher; Alan K. Percy; Steven Skinner; Walter E. Kaufmann; Daniel G. Glaze; Xander H. T. Wehrens; Jeffrey L. Neul
    breathing patterns. To explore the role of Na+ channel blockers on QT in people with RTT, we performed

  5. Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development (�)

    Giudice, Jimena; Xia, Zheng; Scavuzzo, Marissa A.; Ward, Amanda J.; Kalsotra, Auinash; Wang, Wei; Wehrens, Xander H. T.; Burge, Christopher B.; Li, Wei; Cooper, Thomas A.; Wang, Eric Tzy-shi
    During postnatal development the heart undergoes a rapid and dramatic transition to adult function ...). Here we perform deep RNA-sequencing on RNA from cardiomyocytes and cardiac fibroblasts to conduct

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