Osteosarcoma of the Skull Base after Radiation Therapy in a Patient with McCuneAlbright Syndrome: Case Report
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Osteosarcoma of the Skull Base after Radiation Therapy in a Patient with McCuneAlbright Syndrome: Case Report
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| Id. |
18097826 |
| Idioma |
inglés
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| Titulo |
Osteosarcoma of the Skull Base after Radiation Therapy in a Patient with McCuneAlbright Syndrome: Case Report |
| Autor(es) |
Hansen, Marlan R.
Moffat, J. Craig
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| Localización |
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1131834
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| Versión |
1.0 |
| Estado |
Final
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| Descripción |
Sarcomas of the skull base occurring in the field of prior radiotherapy are rare; only a few have been reported in the English literature. We report a fatal osteosarcoma of the skull base arising in a patient with McCuneAlbright syndrome and severe fibrous dysplasia of the skull base 22 years after radiation therapy for a pituitary adenoma. This malignancy fulfills Cahan's criteria for a radiationinduced tumor in that it arose in the radiation field of a pituitary adenoma with a latency of 22 years. The literature on radiationinduced sarcomas of the skull base is reviewed, and the predisposition of patients with isolated fibrous dysplasia or McCuneAlbright syndrome to develop radiationinduced tumors is discussed. Although the risk of radiationinduced malignancy is low in the general population, special consideration should be given when contemplating the use of radiotherapy for benign disease in patients with McCuneAlbright syndrome or isolated fibrous dysplasia.
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| Palabras clave |
Case Report
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| Tipo de recurso |
Text
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| Tipo de Interactividad |
Expositivo
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| Nivel de Interactividad |
muy bajo
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| Audiencia |
Estudiante
Profesor
Autor
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| Estructura |
Atomic |
| Coste |
no
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| Copyright |
sí
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Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA |
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| Fecha de contribución |
04-mar-2008 |
| Contacto |
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