Microsurgery for Potential Radiosurgical Skull Base Lesions: A Retrospective Analysis and Comparison of Results
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Microsurgery for Potential Radiosurgical Skull Base Lesions: A Retrospective Analysis and Comparison of Results
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| Id. |
18097834 |
| Idioma |
inglés
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| Titulo |
Microsurgery for Potential Radiosurgical Skull Base Lesions: A Retrospective Analysis and Comparison of Results |
| Autor(es) |
Nanda, Anil
Jawahar, Ajay
Sathyanarayana, Satish
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| Localización |
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1131842
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| Versión |
1.0 |
| Estado |
Final
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| Descripción |
The outcomes of 26 complex skull base tumors treated with microsurgery were compared with the outcomes of similar tumors treated with radiosurgery as reported in the literature. The University neurosurgery database was searched for patients who underwent microsurgery for the treatment of skull base tumors between 1990 and 2001 at Louisiana State University Health Sciences Center in Shreveport, Louisiana. Twentysix skull base meningiomas treated by microsurgery by the senior author (AN) were identified retrospectively. On imaging, the tumors were well defined and less than 3 cm in the greatest diameter, making them ideal candidates for a radiosurgical procedure had this modality been available. The followup and outcomes of these 26 patients were compared with the published outcomes of similar tumors treated with radiosurgery. Total excision was achieved in 17 (65.3?%) patients. Excision was subtotal in 9 (34.6?%) patients due to the critical locations of their tumors. The median hospital stay for these patients was 4 days (range, 3 to 12 days). Two patients (7.6?%) had transient cerebrospinal fluid leaks from the wound, and 2 (7.6?%) had transient facial paresis. Overall, preoperative symptoms improved in 23 (88.4?%) patients. The median followup was 56 months (range, 3 to 120 months). The overall survival rate for all was 87.2 ± 3.7?% at 50 months. Two patients (7.6?%) subsequently underwent repeat surgery for a recurrent or progressive disease. The actuarial 8year tumor control rate was 86.4 ± 4.4?% using the KaplanMeier method. For small skull base tumors with benign histology, microsurgery is as safe and effective a treatment option as stereotactic radiosurgery. The symptomatic improvement in patients is better with microsurgery than with radiosurgery because the volume of the tumor is reduced immediately. A combined approach using both modalities is usually needed for larger tumors when attempts at total resection would jeopardize the neurologic function of the patient.
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| Palabras clave |
Original Article
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| Tipo de recurso |
Text
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| Tipo de Interactividad |
Expositivo
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| Nivel de Interactividad |
muy bajo
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| Audiencia |
Estudiante
Profesor
Autor
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| Estructura |
Atomic |
| Coste |
no
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| Copyright |
sí
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Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA |
| Requerimientos técnicos |
Browser: Any
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| Fecha de contribución |
04-mar-2008 |
| Contacto |
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