Stretching single RNAs: exact numerical and stochastic simulation methods
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Stretching single RNAs: exact numerical and stochastic simulation methods
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| Id. |
20880358 |
| Titulo |
Stretching single RNAs: exact numerical and stochastic simulation methods |
| Autor(es) |
Liu, Fei
Zhu, Bi-hui
Ou-Yang, Zhong-can
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| Localización |
http://arxiv.org/abs/q-bio/0411010
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| Versión |
1.0 |
| Estado |
Final
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| Descripción |
Exact numerical methods and stochastic simulation methods are developed to
study the force stretching single RNA issue on the secondary structure level in
equilibrium. By computing the force-extension curves on the constant force and
the constant extension ensembles, we find the two independent methods agree
with each other quite well. To show the precision of our methods in predicting
unfolding experiments, the unfolding forces of different RNA molecules under
different experimental conditions are calculated. We find that the ionic
corrections on the RNA free energies alone might not account for the apparent
differences between the theoretical calculations and the experimental data; an
ionic correction to the persistent length of single-stranded RNA should be
necessary.
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| Palabras clave |
Quantitative Biology - Biomolecules
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| Tipo de recurso |
Texto Narrativo
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| Tipo de Interactividad |
Expositivo
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| Nivel de Interactividad |
muy bajo
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| Audiencia |
Estudiante
Profesor
Autor
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| Estructura |
Atomic |
| Coste |
no
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| Copyright |
sí
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| Requerimientos técnicos |
Browser: Any
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| Fecha de contribución |
28-mar-2007 |
| Contacto |
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