The Genetic Code Boolean Lattice
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The Genetic Code Boolean Lattice
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| Id. |
20880378 |
| Titulo |
The Genetic Code Boolean Lattice |
| Autor(es) |
Sanchez, Robersy
Morgado, Eberto
Grau, Ricardo
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| Localización |
http://arxiv.org/abs/q-bio/0412034
Published in MATCH Commun. Math. Comput. Chem 52, 29-46. (2004)
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| Versión |
1.0 |
| Estado |
Final
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| Descripción |
The algebraic structures of the genetic code are most important to obtain
additional information about the semantic code and its applications. In this
paper we define two dual Boolean codon lattices of the genetic code using
hydrogen bond numbers and the chemical types of bases: purines and pyrimidines.
The Boolean lattices reflect the role of hydrophobicity in the distribution of
codon assignments to each amino acid. Particularly, the symmetric images of
codons with adenine as second base coding to hydrophilic amino acids are always
codons with uracil as second base coding to hydrophobic amino acids as they
represented in the Hasse diagrams. The Hamming distance between two codons in
the Hasse diagram reflects the different hydrophobicities between their
respective coded amino acids. Our experiments have demonstrated a small Hamming
distance to the wild type HXB2 of almost all the drug-resistant reported
mutations in HIV protease gene. The human beta-globin mutant genes have also
exhibited similar results. Our research suggests that the Hamming distance
between two genes in the molecular evolution process have a minimal value.
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| Palabras clave |
Quantitative Biology - Quantitative Methods
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| Tipo de recurso |
Texto Narrativo
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| Tipo de Interactividad |
Expositivo
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| Nivel de Interactividad |
muy bajo
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| Audiencia |
Estudiante
Profesor
Autor
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| Estructura |
Atomic |
| Coste |
no
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| Copyright |
sí
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| Requerimientos técnicos |
Browser: Any
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| Fecha de contribución |
28-mar-2007 |
| Contacto |
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