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Divergence and Shannon information in genomes
Chen, Hong-Da
Chang, Chang-Heng
Hsieh, Li-Ching
Lee, Hoong-Chien
Location: http://arxiv.org/abs/q-bio/0412037

Shannon information (SI) and its special case, divergence, are defined for a DNA sequence in terms of probabilities of chemical words in the sequence and are computed for a set of complete genomes highly diverse in length and composition. We find the following: SI (but not divergence) is inversely proportional to sequence length for a random sequence but is length-independent for genomes; the genomic SI is always greater and, for shorter words and longer sequences, hundreds to thousands times greater than the SI in a random sequence whose length and composition match those of the genome; genomic SIs appear to have word-length dependent universal values. The universality is inferred to be an evolution footprint of a universal mode for genome growth.

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Divergence and Shannon information in genomes
Id. 20880381
Titulo Divergence and Shannon information in genomes
Autor(es) Chen, Hong-Da
Chang, Chang-Heng
Hsieh, Li-Ching
Lee, Hoong-Chien
Location http://arxiv.org/abs/q-bio/0412037
Versión 1.0
Estado Final
Descripción Shannon information (SI) and its special case, divergence, are defined for a DNA sequence in terms of probabilities of chemical words in the sequence and are computed for a set of complete genomes highly diverse in length and composition. We find the following: SI (but not divergence) is inversely proportional to sequence length for a random sequence but is length-independent for genomes; the genomic SI is always greater and, for shorter words and longer sequences, hundreds to thousands times greater than the SI in a random sequence whose length and composition match those of the genome; genomic SIs appear to have word-length dependent universal values. The universality is inferred to be an evolution footprint of a universal mode for genome growth.
Palabras clave Quantitative Biology - Genomics
Tipo de recurso Texto Narrativo
Tipo de Interactividad Expositivo
Nivel de Interactividad muy bajo
Audiencia Estudiante
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Estructura Atomic
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Fecha de contribución 28-mar-2007
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