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RECOVERY OF INTENTIONAL DYNAMIC BALANCE FUNCTION AFTER INTRAVENOUS SEDATION WITH MIDAZOLAM IN YOUNG AND ELDERLY SUBJECTS
Fujisawa, Toshiaki
Takuma, Shigeru
Koseki, Hiroyo
Kimura, Kunie
Fukushima, Kazuaki
Location: http://hdl.handle.net/2115/10093
European Journal of Anaesthesiology. 23, 2006, 422-425
http://dx.doi.org/10.1017/S0265021506000019

Background and objective: Computerized dynamic posturography using an intentional postural sway task can be used to assess body-leaning ability and postural control ability to prevent falls. Falls are the leading cause of morbidity and mortality for the elderly. The purpose of the present study was to evaluate the recovery of intentional dynamic balance function after intravenous sedation with midazolam in elderly subjects in comparison with that in young subjects. Methods: Midazolam was administered in small, divided doses over 4 to 5 minutes until the Wilson sedation score reached 3 in 20 young and 18 elderly male volunteers. A dynamic limits of stability test, in which subjects leaned their body intentionally as indicated by a cursor moving on a computer screen, was performed before (baseline) and 50, 70, 90, 110, and 130 minutes after administration of midazolam. Results: The changes from baseline values of path sway and movement time 50 minutes after the administration of midazolam in elderly subjects (106.8?101.0 %, 4.6?3.0 seconds; mean?SD) were significantly greater than those (32.9?87.2%, 1.9?2.8 seconds) in young subjects (p=0.024, p=0.008), respectively. Conclusions: The elderly show slower recovery of the intentional dynamic balance function than do young adults after intravenous sedation with midazolam.

Belongs to: Hokkaido University Collection of Scholarly and Academic Papers

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RECOVERY OF INTENTIONAL DYNAMIC BALANCE FUNCTION AFTER INTRAVENOUS SEDATION WITH MIDAZOLAM IN YOUNG AND ELDERLY SUBJECTS
Id. 5712225
Idioma inglés
Titulo RECOVERY OF INTENTIONAL DYNAMIC BALANCE FUNCTION AFTER INTRAVENOUS SEDATION WITH MIDAZOLAM IN YOUNG AND ELDERLY SUBJECTS
Autor(es) Fujisawa, Toshiaki
Takuma, Shigeru
Koseki, Hiroyo
Kimura, Kunie
Fukushima, Kazuaki
Location http://hdl.handle.net/2115/10093
European Journal of Anaesthesiology. 23, 2006, 422-425
http://dx.doi.org/10.1017/S0265021506000019
Versión 1.0
Estado Final
Descripción Background and objective: Computerized dynamic posturography using an intentional postural sway task can be used to assess body-leaning ability and postural control ability to prevent falls. Falls are the leading cause of morbidity and mortality for the elderly. The purpose of the present study was to evaluate the recovery of intentional dynamic balance function after intravenous sedation with midazolam in elderly subjects in comparison with that in young subjects. Methods: Midazolam was administered in small, divided doses over 4 to 5 minutes until the Wilson sedation score reached 3 in 20 young and 18 elderly male volunteers. A dynamic limits of stability test, in which subjects leaned their body intentionally as indicated by a cursor moving on a computer screen, was performed before (baseline) and 50, 70, 90, 110, and 130 minutes after administration of midazolam. Results: The changes from baseline values of path sway and movement time 50 minutes after the administration of midazolam in elderly subjects (106.8?101.0 %, 4.6?3.0 seconds; mean?SD) were significantly greater than those (32.9?87.2%, 1.9?2.8 seconds) in young subjects (p=0.024, p=0.008), respectively. Conclusions: The elderly show slower recovery of the intentional dynamic balance function than do young adults after intravenous sedation with midazolam.
Tipo 233813 bytes
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Palabras clave CONSCIOUS SEDATION
Tipo de recurso article (author version)
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Nivel de Interactividad muy bajo
Audiencia Estudiante
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Estructura Atomic
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2006 European Journal of Anaethesiology
Formatos 233813 bytes
application/pdf
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Fecha de contribución 25-oct-2007
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