Contemporary management of infected necrosis complicating severe acute pancreatitis
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Contemporary management of infected necrosis complicating severe acute pancreatitis
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| Id. |
7960649 |
| Idioma |
inglés
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| Titulo |
Contemporary management of infected necrosis complicating severe acute pancreatitis |
| Autor(es) |
Jamdar, Saurabh
Siriwardena, Ajith K
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| Localización |
http://www.pubmedcentral.gov/articlerender.fcgi?artid=1550807
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| Versión |
1.0 |
| Estado |
Final
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| Descripción |
Pancreatic necrosis complicating severe acute pancreatitis is a challenging scenario in contemporary critical care practice; it requires multidisciplinary care in a setting where there is a relatively limited evidence base to support decision making. This commentary provides a concise overview of current management of patients with infected necrosis, focusing on detection, the role of pharmacologic intervention, and the timing and nature of surgical interventions. Fine-needle aspiration of necrosis remains the mainstay for establishment of infection. Pharmacological intervention includes antibiotic therapy as an adjunct to surgical debridement/drainage and, more recently, drotrecogin alfa. Specific concerns remain regarding the suitability of drotrecogin alfa in this setting. Early surgical intervention is unhelpful; surgery is indicated when there is strong evidence for infection of necrotic tissue, with the current trend being toward 'less drastic' surgical interventions.
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| Palabras clave |
Commentary
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| Tipo de recurso |
Text
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| Tipo de Interactividad |
Expositivo
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| Nivel de Interactividad |
muy bajo
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| Audiencia |
Estudiante
Profesor
Autor
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| Estructura |
Atomic |
| Coste |
no
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| Copyright |
sí
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| Requerimientos técnicos |
Browser: Any
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| Fecha de contribución |
03-dic-2006 |
| Contacto |
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