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In collective resistance, microbial communities are able to survive antibiotic exposures that would be lethal to individual cells. In this review, we explore recent advances in understanding collective resistance in bacteria. The population dynamics of ‘cheating’ in a system with cooperative antibiotic inactivation have been described, providing insight into the demographic factors that determine resistance allele frequency in bacteria. Extensive work has elucidated mechanisms underlying collective resistance in biofilms and addressed questions about the role of cooperation in these structures. Additionally, recent investigations of ‘bet-hedging’ strategies in bacteria have explored the contributions of stochasticity and regulation to bacterial phenotypic heterogeneity and examined the effects of these strategies on community survival.

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Vega, Nicole -  Gore, Jeff - 

Id.: 69790136

Idioma: inglés (Estados Unidos)  - 

Versión: 1.0

Estado: Final

Tipo de recurso: Article  -  http://purl.org/eprint/type/JournalArticle  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: Creative Commons Attribution-NonCommercial-NoDerivs License

Requerimientos técnicos:  Browser: Any - 

Relación: [IsBasedOn] Elsevier
[References] http://dx.doi.org/10.1016/j.mib.2014.09.003
[References] Current Opinion in Microbiology

Fecha de contribución: 16-abr-2017


* 1369-5274
* Vega, Nicole M and Gore, Jeff. “Collective Antibiotic Resistance: Mechanisms and Implications.” Current Opinion in Microbiology 21 (October 2014): 28–34. © 2014 Elsevier Ltd

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