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The fruit fly, Drosophila melanogaster, is one of the most extensively studied organisms in biological research and has centrioles/basal bodies and cilia that can be modelled to investigate their functions in animals generally. Centrioles are nine-fold symmetrical microtubule-based cylindrical structures required to form centrosomes and also to nucleate the formation of cilia and flagella. When they function to template cilia, centrioles transition into basal bodies. The fruit fly has various types of basal bodies and cilia, which are needed for sensory neuron and sperm function. Genetics, cell biology and behaviour studies in the fruit fly have unveiled new basal body components and revealed different modes of assembly and functions of basal bodies that are conserved in many other organisms, including human, green algae and plasmodium. Here we describe the various basal bodies of Drosophila, what is known about their composition, structure and function.

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ARCA - Access to Research and Communication Annals - IGC Repository  


Jana, Swadhin Chandra -  Bettencourt -  Dias, Mónica -  Durand, Bénédicte -  Megraw, Timothy L. - 

Id.: 65902269

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveCentriole - 

Tipo de recurso: article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: openAccess

Requerimientos técnicos:  Browser: Any - 

Relación: [References] info:eu-repo/grantAgreement/EC/FP7/261344/EU
[References] http://ciliajournal.biomedcentral.com/articles/10.1186/s13630-016-0041-5

Fecha de contribución: 13-jul-2016


* Jana, S. C., Bettencourt-Dias, M., Durand, B., Megraw, T. L. (2016). Drosophila melanogaster as a model for basal body research. Cilia, 5, 22.
* 10.1186/s13630-016-0041-5

Otros recursos de la mismacolección

  1. Maintaining centrosomes and cilia The deposited item is a review and has been submitted to peer review. ...
  2. Tracing the origins of centrioles, cilia, and flagella The uploaded files are the main article and the supplementary material.
  3.  -Tubulin-containing abnormal centrioles are induced by insufficient Plk4 in human HCT116 colorectal cancer cells The article hasn't a creative commons license associated nor informations about funders/sponsors. ...
  4. Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium There is no public supplementary material available.
  5. Centrioles: active players or passengers during mitosis? There is no public supplementary material available.

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