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Descripción

The fruit fly, Drosophila melanogaster, is one of the most extensively studied organisms in biological research and has centrioles/basal bodies and cilia that can be modelled to investigate their functions in animals generally. Centrioles are nine-fold symmetrical microtubule-based cylindrical structures required to form centrosomes and also to nucleate the formation of cilia and flagella. When they function to template cilia, centrioles transition into basal bodies. The fruit fly has various types of basal bodies and cilia, which are needed for sensory neuron and sperm function. Genetics, cell biology and behaviour studies in the fruit fly have unveiled new basal body components and revealed different modes of assembly and functions of basal bodies that are conserved in many other organisms, including human, green algae and plasmodium. Here we describe the various basal bodies of Drosophila, what is known about their composition, structure and function.

Pertenece a

ARCA - Access to Research and Communication Annals - IGC Repository  

Autor(es)

Jana, Swadhin Chandra -  Bettencourt -  Dias, Mónica -  Durand, Bénédicte -  Megraw, Timothy L. - 

Id.: 65902269

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveCentriole - 

Tipo de recurso: article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: openAccess

Requerimientos técnicos:  Browser: Any - 

Relación: [References] info:eu-repo/grantAgreement/EC/FP7/261344/EU
[References] http://ciliajournal.biomedcentral.com/articles/10.1186/s13630-016-0041-5

Fecha de contribución: 13-jul-2016

Contacto:

Localización:
* Jana, S. C., Bettencourt-Dias, M., Durand, B., Megraw, T. L. (2016). Drosophila melanogaster as a model for basal body research. Cilia, 5, 22.
* 10.1186/s13630-016-0041-5

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Otros recursos de la mismacolección

  1. Noncanonical Biogenesis of Centrioles and Basal Bodies The deposited article is a pre-print version.
  2. Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis The uploaded article version is the Epub Ahead of Print version of the article, posted online 8 May ...
  3. Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation This deposit is composed by the main article plus the supplementary materials of the publication.
  4. A mechanism for the elimination of the female gamete centrosome in Drosophila melanogaster The deposited article is a post-print version and has been submitted to peer review.
  5. Evolution: Tracing the origins of centrioles, cilia, and flagella This deposit is composed by the main article plus the supplementary materials of the publication.

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