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In the present work, fast dissolving tablets of fexofenadine HCl were designed with a view to enhance patient compliance by direct compression method. The present work studied the effect of superdisintegrants on release rate of fexofenadine HCl in the form of fast disintegrating tablet. For the present study range of superdisintegrants in their different concentrations, were used. The superdisintegrants used were crosscarmellose sodium, crosspovidone and kyron        T-314. The blends were prepared by direct compression technique. The tablets were evaluated for hardness, thickness, friability, drug content, weight variation and in-vitro drug release studies in pH 6.8.

Keywords: Fexofenadine hydrochloride, fast dissolving tablets, crosscarmellose sodium,

crospovidone, kyron T-314


Pertenece a

Directory of Open Access Journals - Articles  

Autor(es)

kuldeep yogendra desale -  P D Gaikwad -  V H Bankar -  S P Pawar - 

Id.: 65270337

Idioma: English  - 

Versión: 1.0

Estado: Final

Palabras clavePharmaceutical Sciences - 

Tipo de recurso: article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: CC BY

Requerimientos técnicos:  Browser: Any - 

Relación: [IsBasedOn] International Journal of Drug Delivery, Vol 4, Iss 1, Pp 82-88 (2012)
[References] http://arjournals.org/index.php/ijdd/article/view/522
[References] https://doaj.org/toc/0975-0215

Fecha de contribución: 27-abr-2016

Contacto:

Localización:
* 0975-0215
* 10.5138/ijdd.v4i1.522

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