Wednesday, January 28, 2015

 

 



Soy un nuevo usuario

Olvidé mi contraseña

Entrada usuarios

Lógica Matemáticas Astronomía y Astrofísica Física Química Ciencias de la Vida
Ciencias de la Tierra y Espacio Ciencias Agrarias Ciencias Médicas Ciencias Tecnológicas Antropología Demografía
Ciencias Económicas Geografía Historia Ciencias Jurídicas y Derecho Lingüística Pedagogía
Ciencia Política Psicología Artes y Letras Sociología Ética Filosofía


Glutathione Is a Key Player in Metal-Induced Oxidative Stress Defenses

1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario
    registrado en Universia


  Descargar recurso

Detalles del recurso

Pertenece a: Document Server@UHasselt  

Descripción: Since the industrial revolution, the production, and consequently the emission of metals, has increased exponentially, overwhelming the natural cycles of metals in many ecosystems. Metals display a diverse array of physico-chemical properties such as essential versus non-essential and redox-active versus non-redox-active. In general, all metals can lead to toxicity and oxidative stress when taken up in excessive amounts, imposing a serious threat to the environment and human health. In order to cope with different kinds of metals, plants possess defense strategies in which glutathione (GSH; gamma-glu-cys-gly) plays a central role as chelating agent, antioxidant and signaling component. Therefore, this review highlights the role of GSH in: (1) metal homeostasis; (2) antioxidative defense; and (3) signal transduction under metal stress. The diverse functions of GSH originate from the sulfhydryl group in cysteine, enabling GSH to chelate metals and participate in redox cycling.

Autor(es): JOZEFCZAK, Marijke -  REMANS, Tony -  VANGRONSVELD, Jaco -  CUYPERS, Ann - 

Id.: 55229043

Idioma: English  - 

Versión: 1.0

Estado: Final

Tipo:  31 -  application/pdf - 

Palabras clavemetals -  cellular redox state -  glutathione -  chelation - 

Tipo de recurso: Journal Contribution  -  Refereed  -  Review  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

Formatos:  31 -  application/pdf - 

Requerimientos técnicos:  Browser: Any - 

Relación: [References] 10.3390/ijms13033145
[References] 000302174500038

Fecha de contribución: 08-oct-2014

Contacto:

Localización:
* INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 132 (3), p. 3145-3175
* 1422-0067


Otros recursos del mismo autor(es)

  1. Renal cells exposed to cadmium in vitro and in vivo: normalizing gene expression data Cadmium (Cd) is a toxic metal with a long half-life in biological systems. This half-life is partly ...
  2. Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidney Cadmium (Cd2+) induces oxidative stress that ultimately defines cell fate and pathology. Mitochondri...
  3. Reliable gene expression analysis by reverse transcription-quantitative PCR: reporting and minimizing the uncertainty in data accuracy. Reverse transcription-quantitative PCR (RT-qPCR) has been widely adopted to measure differences in m...
  4. Wild Flora of Mine Tailings: Perspectives for Use in Phytoremediation of Potentially Toxic Elements in a Semi-Arid Region in Mexico The aim of this research was to identify wild plant species applicable for remediation of mine taili...
  5. Arabidopsis thaliana seedlings show an age-dependent response on growth and DNA repair after exposure to chronic gamma-radiation The biosphere is constantly exposed to ionising radiation, due to cosmic radiation and the presence ...

Otros recursos de la misma colección

  1. Management of the Cardiorenal Syndrome in Decompensated Heart Failure Background: The management of the cardiorenal syndrome (CRS) in decompensated heart failure (HF) is ...
  2. Implementation of transmural disease management in patients admitted with advanced heart failure Objective The objective of this study was to assess the feasibility and impact on readmissions of tr...
  3. Increased cardiovascular risk in patients with rheumatoid arthritis: an overview Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and morta...
  4. Revision of Phaenocora Ehrenberg, 1836 (Rhabditophora, Typhloplanidae, Phaenocorinae) with the description of two new species A morphological and taxonomical account of the taxon Phaenocora is provided. An effort was made to l...
  5. Carbon loading in airway macrophages as a biomarker for individual exposure to particulate matter air pollution - A critical review Exposure to particulate matter (PM) is associated with adverse health effects, including chronic lun...

Valoración de los usuarios

No hay ninguna valoración para este recurso.Sea el primero en valorar este recurso.
 

Busque un recurso