1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario registrado en Universia

Opción 1: Descargar recurso

Detalles del recurso


An investigation of the Dakin-West reaction has been made, as a result of which the scope of the reaction has been extended in a number of ways.

a. It has been found that a number of aliphatic, aromatic and heterocyclic acid anhydrides, acyl fluorides, and (with the proper choice of catalysts) acid chlorides can be used in place of acetic anhydride in the reaction. Several cyclic anhydrides of dibasic acids have been shown not to react; in­conclusive results were obtained with maleic anhydride.

b. The reaction has been shown not to depend on a specific catalytic action of the pyridine structure, but to be cata­lyzed also by such bases as sodium acetate.

c. Several unusual α-amino acids have been shown to undergo the reaction; conclusions have been drawn as to the failure of several other amino acids to react. It has been shown that dipeptides can be used in place of amino acids.

d. A mechanism for the reaction has been proposed, based on evidence now available.

e. Observations have been made on side reactions of importance to the reaction; a method of utility for purifying the products of the reaction has been developed.

The role of peroxides in mutagenesis has been investigated; several peroxides have proved to be effective for the induction of mutations.

Pertenece a



Cleland, George Horace - 

Id.: 70124869

Versión: 1.0

Estado: Final

Tipo:  application/pdf - 

Tipo de recurso: Thesis  -  NonPeerReviewed  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

Formatos:  application/pdf - 

Requerimientos técnicos:  Browser: Any - 

Relación: [References] http://resolver.caltech.edu/CaltechTHESIS:10062017-132951069
[References] https://thesis.library.caltech.edu/10495/

Fecha de contribución: 07-oct-2017


* Cleland, George Horace (1951) I. An Investigation of the Dakin-West Reaction. II. The Role of Peroxides in Mutagenesis. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:10062017-132951069

Otros recursos que te pueden interesar

  1. Preparation of monospecific anti-PAG antibodies for cattle pregnancy detection: use of synthetic peptides to improve specificity Immunological methods involving pregnancy associated glycoproteins (PAG) are used for cattle pregnan...
  2. Development of a second–order standard addition fluorescence method for the direct determination of riboflavin in human urine samples without previous clean up and separation steps A new strategy for the determination of riboflavin (RF, or vitamin B2) in human urine samples has be...
  3. Molecular characterisation of two known species of Paratylenchus Micoletzky, 1922 from Iran with notes on the validity of Paratylenchus audriellus Brown, 1959 During a survey on pin nematodes in western Iran, two populations of Paratylenchus audriellus and Pa...
  4. Molecular basis of the high-palmitic acid trait in sunflower seed oil Sunflower (Helianthus annuus L.) seed oil with high palmitic acid content has enhanced thermo-oxidat...
  5. Major cereal crops benefit from biological nitrogen fixation when inoculated with the nitrogen-fixing bacterium Pseudomonas protegens Pf-5 X940 Fox, Ana Romina et al.-- Special Issue on Ecophysiology of Pseudomonas .

Otros recursos de la mismacolección

  1. The Total Synthesis of (±)-Friedelin

    The total synthesis of the unsymmetrical pentacyclic triterpene friedlein (10) was completed in 3...

  2. Bacteriophage T4 Transfer RNA

    Two T4-coded nonsense suppressors, psu+a and psu+b, h...

  3. I. The Classification of Exact Quantum Methods for Nonreactive Scattering. II. Quantum Mechanical Calculations of Rotational-Vibrational Scattering in Homonuclear Diatom-Atom Collisions. III. The Effect of the Potential Well on Vibrational Scattering and the Validity of SSH Theory

    Part 1. The exact quantum methods for the cal­culation of nonreactive scattering are classified....

  4. The Effect of pH on the Workability of Concrete

    It was believed that the pH of concrete would affect the workability. The effect of pH on the wor...

  5. Thermo-Acoustic Coupling and Dynamic Response of a Premixed Methane-Air Flame

    The work herein generally applies to the problem of combustion instability. Combustion instabili...

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.