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Descripción

A platform for high spatial and temporal resolution electrophysiological recordings of in vitro electrogenic cell cultures handling 4096 electrodes at a full frame rate of 8 kHz is presented and validated by means of cardiomyocyte cultures. Based on an active pixel sensor device implementing an array of metallic electrodes, the system provides acquisitions at spatial resolutions of 42 µmon an active area of 2.67mm×2.67 mm, and in the zooming mode, temporal resolutions down to 8 µs on 64 randomly selected electrodes. The low-noise performances of the integrated ampli- fier (11 µVrms) combined with a hardware implementation inspired by image/video processing concepts enable high-resolution acquisitions with real-time preprocessing capabilities adapted to the handling of the large amount of acquired data.

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Autor(es)

Imfeld, K. -  Neukom, S. -  Maccione, A. -  Bornat, Y. -  Martinoia, S. -  Farine, P. -  A. -  Koudelka -  Hep, M. -  Berdondini, L. - 

Id.: 70631749

Idioma: inglés  - 

Versión: 1.0

Estado: Final

Palabras clave[SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics - 

Tipo de recurso: info:eu-repo/semantics/article  -  Journal articles  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

Requerimientos técnicos:  Browser: Any - 

Relación: [IsBasedOn] ISSN: 0018-9294
[IsBasedOn] IEEE Transactions on Biomedical Engineering
[IsBasedOn] https://hal.archives-ouvertes.fr/hal-00319351
[IsBasedOn] IEEE Transactions on Biomedical Engineering, Institute of Electrical and Electronics Engineers, 2008, 55 (8), pp.2064-2073

Fecha de contribución: 30-nov-2017

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Localización:
* hal-00319351

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