1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario registrado en Universia

Opción 1: Descargar recurso

Detalles del recurso


While the natural niches of the soil bacterium Pseudomonas putida are unlikely to include significant amounts of free glycerol as a growth substrate, this bacterium is genetically equipped with the functions required for its metabolism. We have resorted to deep sequencing of the transcripts in glycerol-grown P.putidaKT2440 cells to gain an insight into the biochemical and regulatory components involved in the shift between customary C sources (e.g. glucose or succinate) to the polyol. Transcriptomic results were contrasted with key enzymatic activities under the same culture conditions. Cognate expression profiles revealed that genes encoding enzymes of the Entner-Doudoroff route and other catabolic pathways, e.g. the gluconate and 2-ketogluconate loops, were significantly downregulated on glycerol. Yet, the compound simultaneously elicited a gluconeogenic response that indicated an efficient channelling of C skeletons back to biomass build-up through the glyoxylate shunt rather than energization of the cells through downwards pathways, i.e. tricarboxylic acid cycle and oxidative phosphorylation. The simultaneous glycolytic and gluconeogenic metabolic regimes on glycerol, paradoxical as they seem, make sense from an ecological point of view by favouring prevalence versus exploration. This metabolic situation was accompanied by a considerably low expression of stress markers as compared with other C sources. © 2013 Society for Applied Microbiology and John Wiley & Sons Ltd.

Pertenece a



Nikel, P.I. -  Kim, J. -  Lorenzo, Víctor de - 

Id.: 70878023

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveBacterial physiology - 

Tipo de recurso: Artículo  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: openAccess

Requerimientos técnicos:  Browser: Any - 

Relación: [References] Postprint
[References] http://dx.doi.org/10.1111/1462-2920.12224
[References] Sí

Fecha de contribución: 17-ene-2018


* Environmental Microbiology 16: 239- 254 (2014)
* 1462-2912
* 10.1111/1462-2920.12224
* 1462-2920

Otros recursos del mismo autor(es)

  1. Lévy-stable two-pion Bose-Einstein correlations in $\sqrt{s_{_{NN}}}=200$ GeV Au$+$Au collisions International audience
  2. Full band all-sky search for periodic gravitational waves in the O1 LIGO data We report on a new all-sky search for periodic gravitational waves in the frequency band 475–2000 Hz...
  3. Evidence of an early to early-middle Eocene tidal incursion in Southern Amazonia (Madre de Dios Basin, Peru) International audience
  4. Search for Physics Beyond the Standard Model in Events with High-Momentum Higgs Bosons and Missing Transverse Momentum in Proton-Proton Collisions at 13 TeV A search for physics beyond the standard model in events with one or more high-momentum Higgs bosons...
  5. Search for dark matter in events with energetic, hadronically decaying top quarks and missing transverse momentum at √ s = 13 TeV A search for dark matter is conducted in events with large missing transverse momentum and a hadroni...

Otros recursos de la mismacolección

  1. Recruitment DsRed2-PKD1 (red channel) to the immune synapse is more obvious after deconvolution The two movies show a raw (1st movie) and Huygens deconvolved (2nd movie) image series of DsRed2-PKD...
  2. "In -planta" penetration and translocation of Fe@C magnetic nanoparticles Trabajo presentado en la 20th International Conference of Magnetism, celebrada en Barcelona del 5 al...
  3. CD63-positive green vesicles moving towards synapse areas between a Jurkat and two Raji cells Microscope NIKON TE2000 Objective: PlanApo VC 60x NA 1.4 The formation of a double synapse between 1...
  4. Interaction of superparamagnetic nanoparticles and quantum dots with pathogenic fungi: internalization and toxicity profile Trabajo presentado en la 20th International Conference of Magnetism, celebrada en Barcelona del 5 al...
  5. A novel role of syntaxin 3 as a regulator of human cytomegalovirus gene expression Resumen del póster presentado a la EMBO Conference: Cell polarity and membrane dynamics, celebrada e...

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.