1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario registrado en Universia


Opción 1: Descargar recurso

Detalles del recurso

Descripción

BACKGROUND AND PURPOSE: One of the most widely studied perceptual measures of sensory dysfunction in dystonia is the temporal discrimination threshold (TDT) (the shortest interval at which subjects can perceive that there are two stimuli rather than one). However the elevated thresholds described may be due to a number of potential mechanisms as current paradigms test not only temporal discrimination but also extraneous sensory and decision-making parameters. In this study two paradigms designed to better quantify temporal processing are presented and a decision-making model is used to assess the influence of decision strategy. METHODS: 22 patients with cervical dystonia and 22 age-matched controls completed two tasks (i) temporal resolution (a randomized, automated version of existing TDT paradigms) and (ii) interval discrimination (rating the length of two consecutive intervals). RESULTS: In the temporal resolution task patients had delayed (P = 0.021) and more variable (P = 0.013) response times but equivalent discrimination thresholds. Modelling these effects suggested this was due to an increased perceptual decision boundary in dystonia with patients requiring greater evidence before committing to decisions (P = 0.020). Patient performance on the interval discrimination task was normal. CONCLUSIONS: Our work suggests that previously observed abnormalities in TDT may not be due to a selective sensory deficit of temporal processing as decision-making itself is abnormal in cervical dystonia.

Pertenece a

UCL University College London Eprints  

Autor(es)

Sadnicka, A -  Daum, C -  Cordivari, C -  Bhatia, KP -  Rothwell, JC -  Manohar, S -  Edwards, MJ - 

Id.: 69877672

Versión: 1.0

Estado: Final

Palabras clavecervical dystonia, drift diffusion model, millisecond timing, psychophysics, temporal discrimination threshold - 

Tipo de recurso: Article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

Requerimientos técnicos:  Browser: Any - 

Relación: [IsBasedOn] Eur J Neurol , 24 (6) pp. 796-806. (2017)

Fecha de contribución: 29-may-2017

Contacto:

Localización:

Otros recursos de la mismacolección

  1. NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: A report from the AIEOP-AML group.
  2. Early indicators of self-esteem in teenagers: Findings from a nationally representative sample © 2017 Elsevier LtdThis study explored a longitudinal data set of 3096 British sixteen year olds wit...
  3. Students’ preferences for lecturers’ personalities © 2017 UCUThe present study set out to examine students’ preferences for lecturers’ personality as a...
  4. Health Insurance and Children in Low- and Middle-income Countries: A Review © 2017 Economic Society of Australia.We conduct the first systematic review of the impact of health ...
  5. Extra costs of living with a disability: A systematized review and agenda for research. BACKGROUND: There has been a growing interest in disability and poverty on the international researc...

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.