1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario registrado en Universia


Opción 1: Descargar recurso

Detalles del recurso

Descripción

PURPOSE: The aim of this study was to assess the effectiveness and safety of ILUVIEN® in patients with chronic diabetic macular edema (DME) who were insufficiently responsive to prior therapies. METHODS: This is a prospective, nonrandomized, multicenter, open-label, phase 4 pilot study assessing the effectiveness and safety of ILUVIEN® involving 12 patients insufficiently responsive to available therapies. Assessments were performed at screening, baseline, week 1, and months 1, 3, 6, 9, and 12. Demographics, medical/ophthalmic history, prior laser, anti-VEGF, and steroid treatments, and lab tests were recorded at screening. A complete ophthalmic examination and SD-OCT were performed at screening and at all follow-up visits. RESULTS: The patients showed improvements in best-corrected visual acuity (+3.7 letters), with greater improvement among pseudophakic patients (+6.8 letters) compared with phakic patients (-2.5 letters) 12 months after ILUVIEN®. The mean central subfield thickness decrease from baseline to month 12 was statistically significant, with a rapid reduction in the first week. Regarding safety, only 2 patients showed an intraocular pressure (IOP) increase over 25 mm Hg during the study, and the rise in IOP was well managed with eye drops only. CONCLUSIONS: This prospective and pilot study suggests that ILUVIEN® is safe and may be considered effective for chronic DME patients insufficiently responsive to other available therapies as it showed a rapid and sustained improvement of macular edema obtained after treatment with ILUVIEN®.

Pertenece a

Repositório Comum  

Autor(es)

Figueira, J -  Henriques, J -  Amaro, M -  Rosas, V -  Alves, D -  Cunha -  Vaz, J - 

Id.: 69635351

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveRetinopatia Diabética - 

Tipo de recurso: article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: openAccess

Requerimientos técnicos:  Browser: Any - 

Fecha de contribución: 13-feb-2017

Contacto:

Localización:
* Ophthalmic Res. 2017 Feb 9. doi: 10.1159/000455235. [Epub ahead of print]
* 10.1159/000455235

Otros recursos del mismo autor(es)

  1. MR and CT techniques Magnetic resonance imaging (MRI) and computed tomography (CT) are routinely used in female pelvis im...
  2. European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis Endometriosis is a common gynaecological condition of unknown aetiology that primarily affects women...
  3. Transperineal aggressive angiomyxoma A 45-year-old woman with a history of total hysterectomy with adnexal preservation for uterine leiom...
  4. Educação artística e conhecimento da realidade Este estudo teve por objetivo desvelar as possíveis relações entre, consciência de mundo e a naturez...
  5. Análise e aprimoramento da comunicação da empresa TAG : experiências literárias O presente trabalho tem como finalidade propor sugestões de melhorias para a comunicação da empresa ...

Otros recursos de la mismacolección

  1. Resultado do inquérito de satisfação: Registo oncológico info:eu-repo/semantics/publishedVersion
  2. Registo oncológico: O que é e como se faz info:eu-repo/semantics/publishedVersion
  3. Registo oncológico no HVFX Análise Estatística 2011 – 2015 info:eu-repo/semantics/publishedVersion
  4. Senologia no HVFX info:eu-repo/semantics/publishedVersion
  5. Tumores torácicos: Retrato de 5 anos (2011 a 2015) info:eu-repo/semantics/publishedVersion

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.