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Stress and high levels of glucocorticoids during pre- and early postnatal life seem to alter developmental programs that assure dopaminergic transmission in the mesolimbic, mesocortical and nigrostriatal systems. The induced changes are likely to be determined by the ontogenetic state of development of these brain regions at the time of stress exposure and their stability is associated with increased lifetime susceptibility to psychiatric disorders, including drug addiction. This article is intended to serve as a starting point for future studies aimed at the attenuation or reversal of the effects of adverse early life events on dopamine-regulated behaviors.

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RepositóriUM Universidade do Minho  

Autor(es)

Rodrigues, Ana João -  Leão, Pedro -  Carvalho, M. -  Almeida, O. F. X. -  Sousa, Nuno - 

Id.: 54998046

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveProgramming - 

Tipo de recurso: article  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: open access

Requerimientos técnicos:  Browser: Any - 

Relación: [References] http://www.springerlink.com/link-out/?id=3032&code=T76746772852T726

Fecha de contribución: 03-ene-2013

Contacto:

Localización:
* 0033-3158

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