1) La descarga del recurso depende de la página de origen
2) Para poder descargar el recurso, es necesario ser usuario registrado en Universia


Opción 1: Descargar recurso

Detalles del recurso

Descripción

Telomere and telomerase are involved in cellular and organismal ageing and have been related to human diseases. Coronary artery disease is one of the most common age-related health problems in developed countries. Nevertheless, the specific role of cellular ageing in this process is still unclear. In this study, we analyze the possible prognostic value of telomere length and telomerase polymorphisms in a population of 150 middle aged males (mean age 62 ± 7) admitted for acute coronary syndrome who were followed up for more than 600 days. Peripheral blood samples were obtained and relative and comparative qPCR was used to measure telomere length and real time PCR to study the polymorphisms. Two prognostic combined events were defined. Long telomere length was revealed as an independent predictor (protector) of combined event presentation during long term follow up in our patients.

Pertenece a

Digital.CSIC  

Autor(es)

Pérez -  Rivera, José Ángel -  Pabón -  Osuna, Pedro -  Cieza -  Borrella, Clara -  Martín -  Herrero, Francisco -  González -  Porras, José R. -  Sarmiento, Rogelio - 

Id.: 70715038

Idioma: eng  - 

Versión: 1.0

Estado: Final

Palabras claveCardiovascular prognosis - 

Tipo de recurso: Artículo  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

: closedAccess

Requerimientos técnicos:  Browser: Any - 

Relación: [References] Sí

Fecha de contribución: 05-dic-2017

Contacto:

Localización:
* doi: 10.1016/j.mad.2012.09.003
* issn: 0047-6374
* e-issn: 1872-6216
* Mechanisms of Ageing and Development 133(11-12): 695-697 (2012)
* 10.1016/j.mad.2012.09.003

Otros recursos de la mismacolección

  1. Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor Clonal deletion in the thymus by apoptosis is involved in purging the immune system of self‐reactive...
  2. Identificación, expresión y caracterización de peroxidasas ligninolíticas de interés en genomas de basidiomicetos 227 p.-43 fig.-13 tab.-1 anexo con material suplementario
  3. Promiscuous Recognition of a Trypanosoma cruzi CD8 + T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients Background TcTLE is a nonamer peptide from Trypanosoma cruzi KMP-11 protein that is conserved among...
  4. Ecological connectivity shapes quasispecies structure of RNA viruses in an Antarctic lake © 2015 John Wiley & Sons Ltd. RNA viruses exist as complex mixtures of genotypes, known as quasispec...
  5. Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs © 2015 Macmillan Publishers Limited. Epithelial organs develop through tightly coordinated events of...

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.