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Descripción

The creation of salts is a frequently used approach for the modification of physicochemical properties of an active pharmaceutical ingredient. Despite the frequency of application, there has been little research into the structural–property relationships of the final material and the nature of the counterion present. This work reports on five new salts of sulfathiazole and compares the energetics of the intermolecular interactions with variation in the crystal packing motifs.

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Autor(es)

Munshi, Tasnim -  Scowen, Ian -  Seaton, Colin C. -  Thomas, Rayan R. -  Essifaow, Eman A. A. -  Nauha, Elisa - 

Id.: 71373128

Idioma: inglés  - 

Versión: 1.0

Estado: Final

Tipo:  application/pdf - 

Palabras claveF100 Chemistry - 

Tipo de recurso: Article  -  PeerReviewed  - 

Tipo de Interactividad: Expositivo

Nivel de Interactividad: muy bajo

Audiencia: Estudiante  -  Profesor  -  Autor  - 

Estructura: Atomic

Coste: no

Copyright: sí

Formatos:  application/pdf - 

Requerimientos técnicos:  Browser: Any - 

Relación: [References] http://eprints.lincoln.ac.uk/32254/
[References] http://pubs.rsc.org/en/content/articlelanding/2018/ce/c8ce00606g#!divAbstract
[References] 10.1039/c8ce00606g

Fecha de contribución: 05-jun-2018

Contacto:

Localización:
* Munshi, Tasnim and Scowen, Ian and Seaton, Colin C. and Thomas, Rayan R. and Essifaow, Eman A. A. and Nauha, Elisa Structural motifs in salts of sulfathiazole: implications for design of salt forms in pharmaceuticals APIs†. CrystEngComm . ISSN 1466-803

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