Recursos de colección

DSpace at MIT (104.280 recursos)

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Biology (7) - Archived

Mostrando recursos 1 - 20 de 21

  1. 5.95J / 6.982J / 7.59J / 8.395J / 18.094J / 1.95J / 2.978J Teaching College-Level Science and Engineering, Fall 2012

    Rankin, Janet
    This participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. This course is designed for graduate students interested in an academic career, and anyone else interested in teaching. Topics include theories of adult learning; course development; promoting active learning, problem-solving, and critical thinking in students; communicating with a diverse student body; using educational technology to further learning; lecturing; creating effective tests and assignments; and assessment and evaluation. Students research and present a relevant topic of particular interest. The subject is appropriate for both novices and those with teaching experience.

  2. 7.88J / 7.24J / 5.48J / 10.543J Protein Folding Problem, Fall 2007

    King, Jonathan
    This course focuses on the mechanisms by which the amino acid sequence of polypeptide chains (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects.

  3. 10.547J / 7.547J / 15.136J / HST.920J Principles and Practice of Drug Development, Fall 2005

    Cooney, Charles; Rubin, Robert; Finkelstein MD, Stan; Allen, Tom; Sinskey, Anthony
    This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

  4. 7.91J / 7.36J / 20.490J Foundations of Computational and Systems Biology, Spring 2004

    Burge, Christopher; Yaffe, Michael; Woolf, Peter; Keating, Amy
    Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction, and network modeling are covered. Students are also exposed to currently emerging research areas in the fields of computational and systems biology.

  5. 9.09J / 7.29J Cellular Neurobiology, Spring 2005

    Littleton, Troy; Quinn, William
    This course serves as an introduction to the structure and function of the nervous system. Emphasis is placed on the cellular properties of neurons and other excitable cells. Topics covered include the structure and biophysical properties of excitable cells, synaptic transmission, neurochemistry, neurodevelopment, and the integration of information in simple systems and the visual system.

  6. 5.95J / 7.59J / 8.395J / 18.094J Teaching College-Level Science, Spring 2006

    Breslow, Lori
    This seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. Topics include: using current research in student learning to improve teaching; developing courses; lecturing; promoting students' ability to think critically and solve problems; communicating with a diverse student body; using educational technology; creating effective assignments and tests; and utilizing feedback to improve instruction. Students research and teach a topic of particular interest. This subject is appropriate for both novices and those with teaching experience.

  7. 7.60 Cell Biology: Structure and Functions of the Nucleus, Spring 2006

    Sharp, Phillip; Young, Richard
    This course covers the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Topics include Eukaryotic genome structure, function, and expression, processing of RNA, and regulation of the cell cycle. The techniques and logic used to address important problems in nuclear cell biology is emphasized. Lectures cover broad topic areas in nuclear cell biology and class discussions focus on representative papers recently published in the field.

  8. 7.89 Topics in Computational and Systems Biology, Fall 2007

    Burge, Christopher
    This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments. The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB PhD program, for students with an interest in interdisciplinary training and research...

  9. 1.018J / 7.30J Fundamentals of Ecology, Fall 2003

    Chisholm, Sallie W.; Schaider, Laurel
    Basic subject in ecology: understanding the flow of energy and materials through ecosystems, and what regulates the distribution and abundance of organisms. Productivity and biogeochemical cycles in ecosystems; trophic dynamics; community structure and stability; competition and predation; evolution and natural selection; population growth; and physiological ecology. Emphasis on aquatic systems.

  10. 7.341 DNA Damage Checkpoints: The Emergency Brake on the Road to Cancer, Fall 2007

    Reinhardt, Hans Christian; van Vugt, Marcel A.
    The DNA contained in human cells is under constant attack by both exogenous and endogenous agents that can damage one of its three billion base pairs. To cope with this permanent exposure to DNA-damaging agents, such as the sun's radiation or by-products of our normal metabolism, powerful DNA damage checkpoints have evolved that allow organisms to survive this constant assault on their genomes. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understanding of checkpoints that act as powerful emergency brakes to prevent cancer. We will consider basic principles of...

  11. 9.013J / 7.68J Cellular and Molecular Neurobiology: The Brain and Cognitive Sciences III, Spring 2003

    Constantine-Paton, Martha, 1947-; Sheng, Morgan Hwa-Tze; Garrity, Paul A.
    Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity. Includes lectures and exams, and involves presentation and discussion of primary literature. Focus on major concepts and recent advances in experimental neuroscience.

  12. 7.88J / 5.48J / 7.24J / 10.543J Protein Folding Problem, Fall 2003

    King, Jonathan, 1941-; Gossard, D.
    Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and refolding of proteins in vitro; folding intermediates aggregation and competing off-pathway reactions; role of chaperonins, isomerases, and other helper proteins; protein recovery problems in the biotechnology industry; diseases associated with protein folding defects.

  13. BE.010J / 2.790J / 6.025J / 7.38J / 10.010J Introduction to Bioengineering, Spring 2005

    Matsudaira, Paul T.; Belcher, Angela M.; Grodzinsky, Alan J.
    Designed as a freshmen seminar course, faculty from various School of Engineering departments describe the research and educational opportunities specific to and offered by their departments. Background lectures by the BE.010J staff introduce students to the fundamental scientific basis for bioengineering. Specially produced videos provide additional background information that is supplemented with readings from newspaper and magazine articles.

  14. 9.09J / 7.29J Cellular Neurobiology, Spring 2002

    Quinn, William G.; Chess, Andrew
    An introduction to the structure and function of the nervous system. Emphasis placed on the cellular properties of neurons and other excitable cells. Includes the structure and biophysical properties of excitable cells, synaptic transmission, neurochemistry, neurodevelopment, and integration of information in simple systems and the visual system.

  15. 9.110J / 7.92J Neurology, Neuropsychology, and Neurobiology of Aging, Spring 2003

    Corkin, Suzanne; Ingram, Vernon M.
    Lectures and discussions explore the clinical, behavioral, and molecular aspects of brain aging processes in humans. Topics include: loss of memory and other cognitive abilitites in normal aging; neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. Based on lectures, readings taken from the primary literature, and discussions. Students are expected to present topics based on their readings. One written mid-term test and one final examination. Alternate years.

  16. 9.322J / 7.67 Genetic Neurobiology, Fall 2002

    Quinn, William G.; Littleton, J. Troy
    Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans. Alternate years.

  17. 7.013 Introductory Biology, Spring 2005

    Sive, Hazel L.; Jacks, Tyler; Gardel, Claudette L.
    The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.014 focuses on the application of the fundamental principles toward an understanding of human biology....

  18. 7.03 Genetics, Fall 2001

    Kaiser, Chris; Page, David C.
    The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

  19. 7.28 Molecular Biology, Spring 2001

    Baker, Tania A.; Bell, Stephen P.
    Detailed analysis of the biochemical mechanisms that control the maintenance, expression, and evolution of prokaryotic and eukaryotic genomes. Topics covered in lecture and readings of relevant literature include: gene regulation, DNA replication, genetic recombination, and translation. Logic of experimental design and data analysis emphasized. Presentations include both lectures and group discussions of representative papers from the literature.

  20. 7.012 Introduction to Biology, Fall 2001

    Weinberg, Robert A. (Robert Allan), 1942-; Lander, Eric S.; Gardel, Claudette L.; Mischke, Michelle D.
    Cell biology, immunology, neurobiology, and an exploration into current research in cancer, genomics, and molecular medicine.

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