CAPTURA. Repositorio Academico de la Universidad de Chile
(5.176 recursos)
Captura almacena y conserva la producción de conocimiento generado por docentes e investigadores de la Universidad de Chile, y la hace visible desde los portales académicos internacionales.
Mostrando recursos 1 - 14 de 14
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Levels of interleukin-17 in gingival crevicular fluid and in supernatants of cellular cultures of gingival tissue from patients with chronic periodontitis - Vernal, Rolando; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; Puente, Javier; Valenzuela, María Antonieta; Gamonal Aravena, Jorge
Background and Aims: Interleukin-17 (IL-17) is a T-cell-derived cytokine that may play an important role in the initiation or maintenance of the pro-inflammatory response and has recently been found to stimulate osteoclastic resorption. The purpose of the present study was to determine the presence of IL-17 in gingival crevicular fluid (GCF) samples and in the culture supernatants of gingival cells from patients with chronic periodontitis.
Method: GCF samples were collected during 30 s from two sites in 16 patients from periodontally affected sites (probing depth >= 5 mm, attachment loss >= 3 mm). The comparison with healthy controls was carried out...
7.
Effects of metronidazole plus amoxicillin as the only therapy on the microbiological and clinical parameters of untreated chronic periodontitis - López, Néstor J.; Socransky, Sigmund S.; Da Silva, Isabel; Japlit, Michele R.; Haffajee, Anne D.
Aim: To determine the effect of metronidazole plus amoxicillin (M+A) as the sole therapy, on the subgingival microbiota of chronic periodontitis.
Material and Methods: Twenty-two patients with untreated chronic periodontitis were randomly assigned to a group that received M+A for 7 days, or to a group receiving scaling and root planing (SRP) and two placebos. Clinical measurements including sites with plaque, bleeding on probing (BOP), probing depth (PD) and attachment level (AL) were made at baseline, 3, 6, 9 and 12 months. Subgingival plaque samples were taken from all teeth at baseline 3, 6, 9 and 12 months for the counts...
8.
Análisis genético, clínico y molecular de una familia afectada con una malformación del esmalte dental - Urzúa O., Blanca; Ortega P., Ana; Rodríguez M., Luis; Morales B., Irene
Amelogenesis Imperfecta (AI) is a group of conditions
where there is an abnormal formation of enamel in terms of quantity, structure and composition. AI is
clinically and genetically heterogeneous, there are sex linked and autosomal versions, dominant and/
or recessive, with phenotypes of hypoplastic, hypocalcified or hypomature enamel. Only recently,
through clinical, genetic and molecular studies of affected families, phenotypic-genotypic correlations
are being established in this group of anomalies. Aim: To carry out a genetic, clinical and molecular
analysis of a Chilean family affected with an enamel malformation, which probably would
correspond to Amelogenesis Imperfecta Dominant Autosomal (AIDA), of hypoplastic type, resulting
from g.6395G>A mutation in the enamelin...
9.
Differential uPA expression by TGF-beta 1 in gingival fibroblasts - Smith, P. C.; Martínez, J.
Transforming Growth Factor-beta 1 (TGF-beta 1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this growth factor. To investigate this question, we have studied whether TGF-beta 1 may differentially regulate the expression of urokinase at the protein level in primary cultures of fibroblasts derived from healthy gingiva, granulation tissue from gingival wounds, and chronic periodontal disease. We observed that TGF-beta 1 may repress urokinase expression in healthy gingival fibroblasts and promote its production in granulation-tissue fibroblasts. A significant correlation was found between expression of the...
11.
Laterotrusive occlusal schemes and their effect on supra- and infrahyoid electromyographic activity - Valenzuela, S.; Baeza, Mauricio; Miralles, R.; Cavada, Gabriel; Zúñiga, C.; Santander, H.
The objective of this study was to determine the effects of canine guidance and group function on supra- and infrahyoid electromyographic (EMG) activity. The sample included 40 healthy subjects, 20 with bilateral canine guidance and 20 with bilateral group function. Surface electrodes were used to record the integrated EMG (IEMG) activity of the left supra- and infrahyoid muscles during (1) grinding from intercuspal position to lateral edge-to-edge contact position (with canine guidance or group function), (2) static clenching in edge-to-edge lateral contact position with canine guidance or group function, and (3) grinding from lateral edge-to-edge contact position (with canine guidance...
12.
A comparison of the head and cervical posture between the self-balanced position and the Frankfurt method - Armijo Olivo, S.; Jara, X.; Castillo, N.; Alfonso, L.; Schilling, A.; Valenzuela, E.; Frugone Zambra, Raúl; Magee, D.
Head and cervical posture evaluation has been a concern for many years, not only because of the purported relationship that exists between head and cervical posture in the presence of temporomandibular disorders, neck pain and headache, but also because of the biomechanical relationship between the head and cervical spine and dentofacial structures. Many methods have been suggested in an attempt to establish the best way to evaluate the position of the head using teleradiographs and cephalometric analysis. However, there is still no agreement as to which procedure is the best. The objective of this study was to evaluate the differences...
13.
RANKL in human periapical granuloma: possible involvement in periapical bone destruction - Vernal, R.; Dezerega, A .; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; León, R.; Chandía, S.; Silva, A.; Gamonal, Jorge
OBJECTIVES: The cytokine receptor activator of nuclear factor kappa B-ligand (RANKL) has been involved in both the physiological and pathological regulation of osteoclast life span and bone metabolism. Periapical granuloma is a periradicular lesion characterized by periapical bone destruction. The aims of this study were to associate the RANKL mRNA levels to periapical granulomas using the real-time reverse transcriptase-polymerase chain reaction (RT-PCR) technique and to determine the specific cell involved in RANKL synthesis.
METHODS: In eight periapical granuloma and eight periodontal ligament samples from periodontally healthy volunteers, RANKL mRNA was detected by real-time RT-PCR. Expression of RANKL on infiltrate leukocytes was...
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