Recursos de colección

Digital.CSIC (162.855 recursos)

Repositorio institucional del Consejo Superior de Investigaciones Científicas. Digital.CSIC es un depósito de documentos digitales, cuyo objetivo es organizar, archivar, preservar y difundir en modo de acceso abierto la producción intelectual resultante de la actividad investigadora del CSIC.

(IBMB) Artículos post-print

Mostrando recursos 1 - 4 de 4

  1. Sonic hedgehog signaling switches the mode of division in the developing nervous system

    Saade, Murielle; Gutiérrez-Vallejo, Irene; Dréau, G. le; Rabadán, M. Angeles; Míguez, David G.; Buceta, Javier; Martí, Elisa
    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License.
    - 06-dic-2017

  2. Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism

    Pérez-Valle, Jorge; Rothe, Jessica; Primo, Cecilia; Martínez Pastor, Mar; Ariño, Joaquín; Pascual-Ahuir, Amparo; Mulet-Salort, José Miguel; Serrano, Ramón; Yenush, Lynne
    The yeast protein kinases Sat4/Hal4 and Hal5 are required for the plasma membrane stability of the K+ transporter Trk1 and some amino acid and glucose permeases. The transcriptomic analysis presented here indicates alterations in the general control of the metabolism of both nitrogen and carbon. Accordingly, we observed reduced uptake of methionine and leucine in the hal4 hal5 mutant. This decrease correlates with activation of the Gcn2-Gcn4 pathway, as measured by expression of the lacZ gene under the control of the GCN4 promoter. However, with the exception of methionine biosynthetic genes, few amino acid biosynthetic genes are induced in the...
    - 15-dic-2017

  3. Spain's budget neglects research

    Cabrera, Noemí; Raaij, Mark J. van
    Letter.-- Carlos Fenollosa et al.
    - 19-dic-2017

  4. Genetic diversity of North African Thymus algeriensis in Tunisia: Population structure and implication for conservation

    El Hadj Ali, Imen Ben; Guetat, Arbi; Boussaid, Mohamed
    The genetic diversity within and among nine natural populations of Thymus hirtus Willd. subsp. algeriensis (Boiss. et Reut.) Murb. from different geographical and bioclimatic zones were assessed using Random Amplified Polymorphic DNA data. A total of 154 bands were generated from seven selected primers. 141 bands were polymorphic (P=91.56%). The genetic diversity within a population based on Shannon's index which was high (H' pop=0.307) and varied according to bioclimatic zones. Ahigh genetic differentiation among populations (G ST=0.335 and F{cyrillic} ST=0.296) was revealed, suggesting a population isolation and a low level of gene flow among them. The major proportion of the...
    - 19-dic-2017

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