Ruano Rosa, David; Cazorla, Francisco Manuel; Bonilla, Nuria; Martín-Pérez, R.; Vicente, Antonio de; López Herrera, Carlos
This study tested the effectiveness of single and combined applications of Trichoderma and rhizobacterial strains to control white root rot (WRR) caused by Rosellinia necatrix in avocado plants. Three Trichoderma, two T. atroviride and one T. virens monoconidal strains and four bacterial strains (Bacillus subtilis, Pseudomonas pseudoalcaligenes and two P. chlororaphis) were assayed to determine their compatibilities in vitro. In addition, the effects of the bacterial filtrates were evaluated against the Trichoderma strains and reciprocally; these filtrates were applied alone or in combination to determine their effectiveness against R. necatrix. Individual control agents or combinations of them were applied to...
Ortega-Prieto Ana M.; Sheldon, Julie; Grande-Pérez, Ana; Tejero, Héctor; Gregori, Josep Maria; Quer, Josep; Esteban, Juan Ignacio; Esteban, Domingo; Perales, Celia
Lethal mutagenesis, or virus extinction produced by enhanced mutation rates, is under investigation as an antiviral strategy that aims at counteracting the adaptive capacity of viral quasispecies, and avoiding selection of antiviral-escape mutants. To explore lethal mutagenesis of hepatitis C virus (HCV), it is important to establish whether ribavirin, the purine nucleoside analogue used in anti-HCV therapy, acts as a mutagenic agent during virus replication in cell culture. Here we report the effect of ribavirin during serial passages of HCV in human hepatoma Huh-7.5 cells, regarding viral progeny production and complexity of mutant spectra. Ribavirin produced an increase of mutant...
Essafi, A.; Monforte, Antonio J.; García-Mas, Jordi; Martín-Hernández, Ana M.; Díaz-Pendón, Juan A.; Moriones, Enrique
The original publication is available at www.springerlink.com
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