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Dialnet (Difusión de Alertas en la Red) es una plataforma de recursos y servicios documentales, cuyo objetivo fundamental se centra en mejorar la visibilidad y el acceso a la literatura científica hispana a través de Internet.

Ciencias biológicas

Mostrando recursos 1 - 20 de 30.702

  1. Vascularización renal fetal en preeclámpticas severas y embarazadas normotensas

    Reyna Villasmil, Eduardo; Santos Bolívar, Joel; Navarro Briceño, Yolimar; Mejia Montilla, Jorly; Reyna Villasmil, Nadia; Fernández Ramírez, Andreina; Rondón Tapía, Marta
    The objective of research was to compare renal vascularization in fetus of severe preeclamptic patients with normotensive pregnant women. A case-control study was done at Hospital Central “Dr. Urquinaona”, Maracaibo, Venezuela, with 50 severe preeclamptic patients (grupo A) and 50 normotensive pregnant women (group B), all nulliparous and with gestational age over 30 weeks. Tridimensional and power Doppler evaluation was performed in each fetal kidney separately to calculate vascular indexes: vascularization index, flow index and vascularization – flow index. There were not found significant differences in maternal age and gestational age (p = ns). There were found significant differences in...

  2. Sonda de foley transcervical o misoprostol vaginal para la inducción del parto en embarazos a término: un estudio al azar

    Rosado Tovar, María; Reyna Villasmil, Eduardo; Santos Bolívar, Joel; Mejia Montilla, Jorly; Reyna Villasmil, Nadia; Fernández Ramírez, Andreina
    The objective of research was to compare the effectiveness of transcervical Foley catheter with vaginal misoprostol for labor induction in term pregnancies. Patients undergoing cervical ripening and induction of labor were selected and randomly assigned to be treated with transcervical Foley catheter (Foley group) or vaginal misoprostol (misoprsotol group) who attended to cervical maturation and labor induction at Hospital Central “Dr. Urquinaona”, Maracaibo, Venezuela. Interval between beginning of induction to delivery, vaginal birth rate, maternal complications perinatal variables and adverse effects were evaluated. Patients of Foley group showed a longer interval between beginning of induction to delivery compared with patients...

  3. Embarazo ectópico crónico

    Reyna Villasmil, Eduardo; Torres Cepeda, Duly; Santos Bolívar, Joel; Labarca Acosta, María
    Chronic ectopic pregnancy is a form of tubal pregnancy in which minor ruptures or abortions of an ectopic pregnancy instead of a single episode of bleeding, produces an inflammatory response leading to a pelvic tumor formation. Its clinical features and laboratory evaluations are often confusing. Diagnosis of this enigmatic clinical condition is made during surgery. We describe a case of a 38-year-old woman who presented intermittent lower abdominal pain of 5 months duration. There was no preceding amenorrhea and previous menstrual cycles were regular. Chorionic gonadotropin test was negative and tumor markers were within normal limits. Pelvic ultrasound and tomography...

  4. Descripción de factores de riesgo para enfermedades crónicas no transmisibles en estudiantes de la Universidad Central de Venezuela, 2013

    Cordero, Raimundo; Casañas, Roberto; Rodríguez, Armando; Oporto, Paola; Rendón, Griseth; Zapata, Julielsy; García Avendaño, Pedro
    The aim of this study is to characterize a sample of students from the Central University of Venezuela, according to their socioeconomic status, physical activity, psychobiological habits, family history and cardio-metabolic and anthropometric biomarkers to be used as indicators of risk for Chronic Non Communicable (NCCD). This is a descriptive and cross-sectional study; the sample was 152 students aged between 18 and 29 years. Socioeconomic data, physical activity, psycho-biological characteristics and family medical history were collected by questionnaire. The variables measured were weight, height and waist circumference. Body Mass Index (BMI) and waist-height index was calculated. Cardiometabolic markers were quantified...

  5. Experimentación con biomodelos animales en ciencias de la salud

    Maldonado Villamizar, Johana; Aquino Guerra, Anadela
    Scientific practice in animal testing is a basic and fundamental to generate new advances in health science that relates activity. This practice should be carried out under compliance with established protocols and regulations that determine the appropriate ethical conduct that every professional should be conceived as dogma in his scientific work. In different countries today recognize these perspectives on the moral responsibility that exists in animal experimentation, which creates dilemmas for those who justify their use for scientific research and those who completely repudiate these practices despite the benefits they have provided to humanity. In view of the above, the...

  6. Diagnóstico prenatal de quiste de Cavum Velum Interpositum

    Navarro Briceño, Yolimar; Santos Bolívar, Joel; Reyna Villasmil, Eduardo
    Los quistes intracraneales de la línea media anterior se pueden encontrar en tres formas: cavum septum pellucidum, cavum vergae y cavum velum interpositum. El quiste del cavum velum interpositum representa un espacio lleno de líquido cefalorraquídeo formado por el cuerpo calloso y el fórnix por arriba, el techo del tercer ventrículo, el tálamo por debajo y el fórnix a cada lado. Se presenta un caso de una embarazada de 28 años quien acude a la consulta prenatal a las 30 semanas. Durante la evaluación ecográfica se consigue una lesión quística anecoica, de 25 milímetros de diámetro, intracraneal, interhemisférica inferior al cuerpo...

  7. Desarrollo de un ensayo casero para la detección de IgG contra el core del virus de la Hepatitis B

    Márquez, Yismelvy; Bastidas Azuaje, Miguel Alejandro; Terán Angel, Guillermo; Silva Gutiérrez, Nubia; Colmenares, Melisa; Márquez, Marta; Bellorin, Ana Victoria; Volcanes, Ingrid; Guzmán Escalona, Yanett; Calderón, Ali; Cantor, Astrid; Salmen, Siham
    Hepatitis B infection affects individuals worldwide, especially in Latin America. Serological assay for HBV antibodies and antigen detection, are critical for HBV diagnostic and treatment. Available commercial ELISA kits are expensive and in our country not always are readily available. The aim of this study was develop a homemade ELISA kit for serological detection IgG anti-HBV core (IgG anti-HBc) accessible for our patients. 114 samples were analyzed: 17 from seronegatives individuals, 48 from seropositives patients and 49 belonging to indigenous population from Mérida State. Exposure to Hepatitis B virus was determined using the Murex anti-HBc test (DiaSorin, UK). Homemade ELISA...

  8. Prevalencia y nivel de concordancia entre tres definiciones de síndrome metabólico en la ciudad de Cuenca-Ecuador

    Vásquez C., María A.; Altamirano Cordero, Luisa Cecilia; Álvarez, Robert; Valdiviezo, Aquiles; Cordero, Gabriela; Añez, Roberto; Rojas, Joselyn; Bermúdez, Valmore
    The aim of this research is to realize a comparative study of the prevalence of Metabolic Syndrome (MS) according to the ALAD, ATPIII-2005 and IDF/NHLBI/AHA-2009 criteria in the adult urban population of Cuenca-Ecuador. This is an analytical, cross-sectional study with randomized, multistaged sampling, realized in the city of Cuenca-Ecuador, in 318 subjects of both genders, aged 18 years and older. MS prevalence was estimated with ALAD, ATPIII-2005 and IDF/NHLBI/AHA-2009 criteria. The level of agreement was assessed with Cohen’s Kappa. The prevalence of MS was 51.6% (n=164) according to IDF/NHLBI/AHA-2009 criteria, 43.4% (n=138) by ATPIII criteria, and 43.4% (n=138) by ALAD...

  9. Cutis laxa autosómica recesiva Descripción fenotípica de un caso y revisión de la literatura

    Lacruz de Ortega, María Angelina; Da Silva, Gloria; Guerrero, Diana; Quintero, Edimar; Ordoñez, Yuri; Cammarata Scalisi, Francisco R.
    Cutis laxa is a rare skin disorder, characterized by redundant, inelastic and with an appearance of premature aging. It can be associated with the alteration of other organs involved in their prognosis. It can be inherited or acquired form, local or generalized. It has an estimated incidence of 1 in 1,000,000 births. Genetic studies have discovered a gene network growing required for biogenesis of the elastic fiber in the extracellular matrix and its involvement in the homeostatic maintenance of this integral component of the dermal connective tissue may be involved in the pathophysiology of this entity. We present a case...

  10. Angiosarcoma primario de mama con metástasis en ovario y axila: un patrón inusual de enfermedad metastásica

    Cea García, Jorge; Albalat Fernández, Rosa; Carrión Jiménez, Inmaculada; Pabón Carrasco, Sara
    Primary angiosarcoma of the breast is an uncommon, aggressive neoplasm with an unknown etiology. In this paper, we present a case of a 28 year woman who initially developed primary angiosarcoma of the breast and ovary, followed twenty months later by metastasis to the axilla. Only a few cases of primary angiosarcomas of the breast have reported metastasis to the ovary. Of these cases, all had ovarian metastasis at presentation or shortly after initial diagnosis. This particular case is unusual, the metastases occurred two years following treatment of the primary tumor. This paper will address possible factors contributing to metastasis.

  11. Estudio piloto de los factores clásicos de riesgo cardiovascular en una comunidad rural del municipio San Diego, Venezuela

    Querales, Marvin; Rojas, Susan; Romero, Gabriela; Ramírez, José
    Cardiovascular diseases represent a public health problem in both developed and undeveloped countries. These illnesses, although they have been more associated with urban populations, have shown an increase in rural communities. For this, the objective of this research was to make a preliminary diagnosis of classical cardiovascular risk factors in a rural community from San Diego, Venezuela. 185 people who were determined weight, height, waist circumference, blood pressure, blood glucose and lipid profile were evaluated. A survey to assess family history of cardiovascular disease and lifestyle was applied. High frequency of sedentary lifestyle and low HDL cholesterol (90%, CI=86,0-94,6), overweight/obesity...

  12. Deshidrogenasa láctica sérica en preeclámpticas y embarazadas normotensas

    Vargas García, Avelin; Reyna Villasmil, Eduardo; Mejia Montilla, Jorly; Reyna Villasmil, Nadia; Santos Bolívar, Joel; Fernández Ramírez, Andreina
    The objective of research was to compare serum lactic dehydrogenase in preeclamptic patients and healthy normotensive pregnant women. A total of 180 patients were selected. Ninety preeclamptic patients were selected as the study group (group A) and 90 healthy normotensive pregnant women with the same age and body mass index as the study group were selected as controls (group B). Blood samples were extracted from all patients before labor and immediately after diagnosis in group A to determine serum lactic dehydrogenase concentrations. There was statistically significant difference in serum lactic dehydrogenase concentrations between group A (523.9 +/- 131.7 UI/L) and...

  13. Stabilization of the metaphase spindle by Cdc14 is required for recombinational DNA repair

    Villoria, María Teresa; Ramos, Facundo; Dueñas, Encarnación; Faull, Peter; Rodríguez Cutillas, Pedro; Clemente‐Blanco, Andrés
    Cells are constantly threatened by multiple sources of genotoxic stress that cause DNA damage. To maintain genome integrity, cells have developed a coordinated signalling network called DNA damage response (DDR). While multiple kinases have been thoroughly studied during DDR activation, the role of protein dephosphorylation in the damage response remains elusive. Here, we show that the phosphatase Cdc14 is essential to fulfil recombinational DNA repair in budding yeast. After DNA double‐strand break (DSB) generation, Cdc14 is transiently released from the nucleolus and activated. In this state, Cdc14 targets the spindle pole body (SPB) component Spc110 to counterbalance its phosphorylation by cyclin‐dependent...

  14. Aryl hydrocarbon receptor is required for optimal B‐cell proliferation

    Villa, Matteo; Gialitakis, Manolis; Tolaini, Mauro; Ahlfors, Helena; Henderson, Colin J; Wolf, C Roland; Brink, Robert; Stockinger, Brigitta
    The aryl hydrocarbon receptor (AhR), a transcription factor known for mediating xenobiotic toxicity, is expressed in B cells, which are known targets for environmental pollutants. However, it is unclear what the physiological functions of AhR in B cells are. We show here that expression of Ahr in B cells is up‐regulated upon B‐cell receptor (BCR) engagement and IL‐4 treatment. Addition of a natural ligand of AhR, FICZ, induces AhR translocation to the nucleus and transcription of the AhR target gene Cyp1a1, showing that the AhR pathway is functional in B cells. AhR‐deficient (Ahr −/−) B cells proliferate less than AhR‐sufficient (Ahr +/+)...

  15. Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos

    Raisch, Tobias; Bhandari, Dipankar; Sabath, Kevin; Helms, Sigrun; Valkov, Eugene; Weichenrieder, Oliver; Izaurralde, Elisa
    Nanos proteins repress the expression of target mRNAs by recruiting effector complexes through non‐conserved N‐terminal regions. In vertebrates, Nanos proteins interact with the NOT1 subunit of the CCR4–NOT effector complex through a NOT1 interacting motif (NIM), which is absent in Nanos orthologs from several invertebrate species. Therefore, it has remained unclear whether the Nanos repressive mechanism is conserved and whether it also involves direct interactions with the CCR4–NOT deadenylase complex in invertebrates. Here, we identify an effector domain (NED) that is necessary for the Drosophila melanogaster (Dm) Nanos to repress mRNA targets. The NED recruits the CCR4–NOT complex through multiple...

  16. Global RNA recognition patterns of post‐transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo

    Holmqvist, Erik; Wright, Patrick R; Li, Lei; Bischler, Thorsten; Barquist, Lars; Reinhardt, Richard; Backofen, Rolf; Vogel, Jörg
    The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA deep sequencing (CLIP‐seq) have begun to revolutionize the transcriptome‐wide mapping of eukaryotic RNA‐binding protein target sites. We have applied CLIP‐seq to chart the target landscape of two major bacterial post‐transcriptional regulators, Hfq and CsrA, in the model pathogen Salmonella Typhimurium. By detecting binding sites at single‐nucleotide resolution, we identify RNA preferences and structural constraints of Hfq and CsrA during their interactions with hundreds of cellular transcripts. This reveals 3′‐located Rho‐independent terminators as a universal motif involved in...

  17. Influence of a carp invasion on the zooplankton community in Laguna Medina, a Mediterranean shallow lake

    Florian, Norbert; López, Raquel; Ospina Alvarez, Natalia; Hufnagel, Levente; Green, Andy J.
    The common carp (Cyprinus carpio) is a highly invasive species and an ecological engineer. It has been repeatedly shown to increase nutrient concentrations and phytoplankton biomass while destroying submerged macrophytes, although there are few studies from the Mediterranean region. We studied its impact on the zooplankton community in Laguna de Medina lake, a shallow lake in Jerez de la Frontera, south-west Spain. Carp were removed with rotenone in 2007 but returned in 2010-2011. We compared zooplankton sampled monthly from 8 points from May to December in 2008 (without carp) and 2012 (with carp). Extensive macrophyte beds present in 2008 were...

  18. Assessing the influence of environmental parameters on aquatic plants of ponds in the hinterland of Long Beach in Montenegro

    Bubanja, Nada; Sinzar-Sekulic, Jasmina; Stevanovic, Vladimir
    The distribution and richness of aquatic plants in 19 ponds in the hinterland of Long Beach and Ada Bojana Island in the southern part of Montenegro in the period from March 2014 to October 2014 have been studied in relation to some environmental factors. The presence of 74 species was recorded, 10 of which were submerged, 4 floating-leaved and 60 emergent plants. Phragmites australis was the most frequent species that is present in 16 of the analysed ponds. The results of Canonical Correspondence Analysis (CCA) have shown that statistically significant physicochemical parameters (concentration of nitrates, distance from the sea and...

  19. Temporary emersion enhances amphibious Isoetes production

    Chappuis, Eglantine; Ballesteros, E.; Gacia, Esperança
    Annual primary production of two amphibious quillworts was measured in two contrasting temporary environments in NE Spain: Isoetes echinospora growing in a high mountain semipermanent pool and Isoetes delilei growing in a Mediterranean pool. Leaf primary production showed a unimodal distribution with a peak in July for I. echinospora and in April for I. delilei. The population of I. echinospora produced 38.7 g DW m–2y–1 (15.5 g C m–2y–1) of leaves the year of complete submersion, but leaf production increased to 49.3 g DW m–2y–1 (19.7 g C m–2y–1) the year with two months of emersion (27.4% increase). Leaf production...

  20. Critical swimming speed of the southern straight-mouth nase Pseudochondrostoma willkommii (Steindachner, 1866), a potamodromous cyprinid from southern Europe

    Alexandre, Carlos M.; Branca, R.; Quintella, Bernardo Ruivo; Almeida, Pedro R.
    Critical swimming speed (Ucrit) of the potamodromous southern straight-mouth nase was assessed in a modified Blazka-type swim tunnel. Forty-one P. willkommii were tested and exhibited a mean± SD Ucrit of 0.54 ± 0.07 m/s. The sex of experimental fish had no effect on Ucrit but a significant positive relationship was found between swimming performance and the body condition of tested fish. Results from this study can be used to improve the current design of fish passes targeting this, or similar, potamodromous fish species.

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