PubMed Central (PMC3 - NLM DTD)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
Mostrando recursos 1 - 20 de 193
Lemierre Syndrome—Should We Anticoagulate? A Case Report and Review of the Literature - Phua, C.K.; Chadachan, V.M.; Acharya, R.
Lemierre syndrome is an uncommon condition classically described in acute oropharyngeal infection with septic thrombophlebitis of the internal jugular vein and metastatic septic embolism particularly to the lungs. It is commonly described in young healthy adults with isolation of Fusobacterium necrophorum. We describe a case of Lemierre syndrome in a 50-year-old man with newly diagnosed diabetes mellitus presenting with a neck abscess secondary to Klebsiella pneumoniae. Our patient made good recovery to appropriate antimicrobial therapy, prompt surgical drainage, and anticoagulation. Anticoagulation remains controversial and we review the literature for its role in Lemierre syndrome.
Posttraumatic versus Mycotic Dorsalis Pedis Pseudoaneurysm - Lynch, James E.; Winkler, Katrina A.; Xenos, Eleftherios
Reports of dorsalis pedis aneurysms are rare, and there are currently no reports of mycotic dorsalis pedis aneurysms in the literature. Most dorsalis pedis pseudoaneurysms are diagnosed by physical exam and color flow duplex. Surgical treatment includes aneurysm resection with or without reconstruction of the dorsalis pedis artery. We report a dorsalis pedis pseudoaneurysm diagnosed clinically and via duplex ultrasound, treated by excision and ligation of the aneurysm.
Shortened Length of Stay Improves Financial Outcomes in Living Donor Kidney Transplantation - Villa, Manuel; Siskind, Eric; Sameyah, Emil; Alex, Asha; Blum, Mark; Tyrell, Richard; Fana, Melissa; Mishler, Marni; Godwin, Andrew; Kuncewitch, Michael; Alexander, Mohini; Israel, Ezra; Bhaskaran, Madhu; Calderon, Kellie; Jhaveri, Kenar D.; Sachdeva, Mala; Bellucci, Alessandro; Mattana, Joseph; Fishbane, Steven; Coppa, Gene; Molmenti, Ernesto
Kidney transplantation is the preferred clinical and most cost-effective option for end-stage renal disease. Significant advances have taken place in the care of the transplant patients with improvements in clinical outcomes. The optimization of the costs of transplantation has been a constant goal as well. We present herein the impact in financial outcomes of a shortened length of stay after kidney transplant.
A Case Series of HIV-Seropositive Patients and Hypercoagulable State—Is It Difficult to Treat Even with Therapeutic Anticoagulation? - Sule, Ashish Anil; Pandit, Nihar; Handa, Pankaj; Chadachan, Veerandra; Tan, Endean; Sum, Faith Nadine Choo Yun; Joyce, Er Hui Ling; Chin, Tay Jam
Patients with human immunodeficiency virus (HIV) are at risk of developing thrombosis and are 8 to 10 times more likely to develop thrombosis than the general population. Moreover, if they have hypercoagulable state they can have severe thrombosis and life-threatening thrombotic events. The purpose of this retrospective study is to analyze hypercoagulable state in HIV-seropositive patients who have been diagnosed with venous thromboembolism (VTE). This study is a subgroup study of a larger cohort group of HIV-seropositive patients with VTE followed up with our vascular medicine outpatient clinic. The patients included for this study were HIV-seropositive patients with hypercoagulable state,...
Clinical Significance of Conditions Presenting with ECG Changes Mimicking Acute Myocardial Infarction - Yahalom, Malka; Roguin, Nathan; Suleiman, Khaled; Turgeman, Yoav
The electrocardiogram (ECG) is the primary tool in the diagnosis of acute myocardial infarction (AMI). However, other clinical conditions, both cardiac and noncardiac originated pathologies, may result in ECG tracing of AMI. This may lead to an incorrect diagnosis, exposing the patients to unnecessary tests and potentially harmful therapeutic procedures. The aim of this report is to increase the still insufficient awareness of clinicians from multiple disciplines, regarding the different clinical syndromes, both cardiac and noncardiac, associated with ECG abnormalities mimicking AMI, to avoid unjustified thrombolytic therapy or intervention procedures. During a 9-year period, the data from six patients (five...
Endovascular Repair of a Traumatic Thoracic Aortic Injury Resulting in Late Aortic Dilatation - Ozaki, Kumi; Matsui, Osamu; Ohtake, Hiroshi; Watanabe, Go; anada, Junichiro
We present an unusual complication following endovascular repair of traumatic thoracic aortic injury using a homemade stent-graft. Although an initial technical success was apparently obtained, the aorta showed remarkable dilatation without shortening or migration of the stent skeleton in late follow-up period. The possible cause of the dilatation was considered to be the expansion and gathering of the crimped, loosely attached, graft fabric in addition to the incomplete exclusion due to the insufficient landing zone and the limited radial force. Thus, the specific feature of stent-graft, considered to provide an advantage to treatment, has adversely affected the native aorta.
Risk of Venous Thromboembolism in Patients Infected with HIV: A Cohort Study - Sule, Ashish Anil; Pandit, Nihar; Handa, Pankaj; Chadachan, Veerandra; Tan, Endean; Sum, Faith Nadine Choo Yun; Joyce, Er Hui Ling; Chin, Tay Jam
Introduction Human immunodeficiency virus (HIV) patients are at risk of developing thrombosis than general population. There are several intersecting mechanisms associated with HIV infection and antiviral therapy that are emerging, which may lead to vasculopathy and hypercoagulability in these patients.
Acute Limb Ischemia: Surgical Thromboembolectomy and the Clinical Course of Arterial Revascularization at Ankle - Shin, Ha Song; Kyoung, Kyu-Hyouck; Suh, Byoung Jo; Jun, Si-Youl; Park, Jong Kwon
Surgical thromboembolectomy for acute limb ischemia using Fogarty catheter is basically a blind procedure. Therefore, the complete removal of thromboemboli in all calf arteries is difficult even if completion angiography or radiological intervention is performed. The purpose of this study is to identify whether limb salvage could be achieved if at least one ankle artery was revascularized by surgical thromboembolectomy. We also observed the effectiveness of below-knee popliteal approach. Over 1 year, surgical thromboembolectomy via below-knee popliteal artery was performed on 18 acutely ischemic limbs in 14 consecutive patients. All patients were diagnosed based on clinical symptoms and computed tomography...
Left Innominate Vein Aneurysm: Diagnostic Imaging and Pitfalls - Buehler, Mark A.; Ebrahim, Farhad S.; Popa, Theodore O.
Thoracic venous aneurysms are very rare. They may be asymptomatic and can be found incidentally during imaging. They are associated with few complications including pulmonary embolism, rupture, and venous obstruction. Accurate diagnosis of a mediastinal aneurysm is essential to avoid complications secondary to biopsy or surgical intervention. This is a rare case of left innominate vein aneurysm, its imaging, as well as associated imaging shortfalls.
Problems and Possible Solutions for Therapy with Statins - Whayne, Thomas F.
Despite issues about the value of statins, benefit for high cardiovascular (CV) risk outweighs problems. However, the practitioner must be aware of concerns, be prepared to respond, and justify statin usage. Symptoms of statin-related myopathy are of more concern than stated by pharmaceutical companies. Occurrence of myopathy symptoms, estimated to be up to 10.4%, can decrease statin adherence of high CV risk patients. Dosage modification, or use of pitavastatin, may help the problematic patient. There are concerns that there may be little benefit of statins for primary prevention in women. However, evidence appears to support statin use in women at...
“STOP, LOOK, and LISTEN.” Hepatic Portal Venous Gas: Time for Clinical Assessment! - Villa, Manuel; Ranade, Ajay N.; Jaimes-Vanegas, Natalia; Walden, Heath; D'Agostino, Catherine A.; Nicastro, Jeffrey; Coppa, Gene F.; Sideridis, Kostas; Molmenti, Ernesto P.; Bagdonas, Richard A.
Pneumatosis intestinalis and portal venous gas are findings usually associated with intra-abdominal surgical catastrophes that frequently require emergent surgical intervention. Herein we present a case of a patient who presented in septic shock, with extensive portal vein gas, diffuse intestinal wall thickening, and atherosclerotic vascular insufficiency in the absence of pneumatosis intestinalis.
The Significance of Bradycardia in Anorexia Nervosa - Yahalom, Malka; Spitz, Marcelo; Sandler, Ludmila; Heno, Nawaf; Roguin, Nathan; Turgeman, Yoav
Anorexia nervosa (AN) is a life-threatening condition, with a significant risk for death, due to cardiovascular complications. It is characterized by abnormal eating behavior and has the highest mortality rate of all psychiatric disorders. It has been associated with bradycardia (a heart rate [HR] of less than 60 beats per minute) (up to 95%), hypotension, mitral valve prolapse, and heart failure. The diagnosis of AN can be elusive, and more than half of all cases are undetected. The purpose of this study was to raise and improve awareness to the possible diagnosis of AN in adolescent and young adult patients...
Subclavian Aneurysm Presenting with Massive Hemoptysis: A Case Report and Review of the Literature - Brown, Hilary A.; Aruny, John E.; Elefteriades, John A.; Sumpio, Bauer E.
We present a case of a 70-year-old male with a past medical history of coronary artery bypass grafting and end stage renal disease who presented with massive hemoptysis. He had a history of methicillin-resistant Staphylococcus aureus endocarditis, with infection and removal of endocardial pacing leads. His work-up revealed a 2.9-cm proximal left subclavian artery aneurysm. Bronchoscopy confirmed bright red blood in the left upper lobe bronchus and coronary angiography confirmed a patent left internal mammary artery (LIMA) to left anterior descending bypass. Because of the consideration of maintaining coronary perfusion via the LIMA while excluding the subclavian aneurysm, he underwent...
An Overview of Optimal Endovascular Strategy in Treating the Femoropopliteal Artery: Mechanical, Biological, and Procedural Factors - Shammas, Nicolas W.
Treatment of the femoropopliteal (FP) artery remains a challenge to the endovascular specialist. Long-term patency is low with a high rate of target lesion revascularization. The true patency rate varies considerably between studies partly because there is a lack of uniform performance criteria and reporting standards in peripheral arterial interventions. Literature review supports three principles that emerge as important components of an optimal strategy in treating the FP artery: (1) improving vessel compliance and subsequently less dissections and bailout stenting, (2) reducing smooth muscle cell proliferation, and (3) protecting outflow vessels from distal embolization. In this overview, we examine current...
Endovascular Treatment versus Open Repair for Abdominal Aortic Aneurysms: The Influence of Fitness in Decision Making - Moulakakis, Konstnatinos G.; Dalainas, Ilias; Kakisis, John; Mylonas, Spyridon; Liapis, Christos D.
Two methods of repair are currently available for an abdominal aortic aneurysm (AAA), open aneurysm repair and endovascular aneurysm repair (EVAR). The decision making depends on the balance of risks and benefits. The treating physician must take into account the patient's life expectancy, the patient's fitness, the anatomic suitability that makes endovascular repair possible, and finally the patient's preference. The patient's fitness is an important variable predicting the outcome of AAA surgical reconstruction. The hypothesis is that the impact of risk factors upon perioperative mortality might differ between patients undergoing open repair and endovascular repair. The purpose of this review...
Calf Pump Activity Influencing Venous Hemodynamics in the Lower Extremity - Recek, Cestmir
Calf muscle pump is the motive force enhancing return of venous blood from the lower extremity to the heart. It causes displacement of venous blood in both vertical and horizontal directions, generates ambulatory pressure gradient between thigh and lower leg veins, and bidirectional streaming within calf perforators. Ambulatory pressure gradient triggers venous reflux in incompetent veins, which induces ambulatory venous hypertension in the lower leg and foot. Bidirectional flow in calf perforators enables quick pressure equalization between deep and superficial veins of the lower leg; the outward (into the superficial veins) oriented component of the bidirectional flow taking place during...
The Dynamic Function of the Atrial Diastole of the Heart and Motion of Venous Valves in Humans - Rai, Dinker B.
This study demonstrates dynamic function of atrial diastole for the first time in the history of medicine, following the revelation of ventricular function by Sir William Harvey. This study consists of two parts. First part is the study of humans and the discovery of the rhythmic opening and closing of venous valves in the femoral vein segment during each cardiac cycle under fluoroscopy. Its relationship to the right atrial diastole is discussed. Second part is an experimental model developed in a dog's heart. Experiments are conducted in an erect posture, in which the right atrium is partially and totally isolated...
Removal of Foley Catheters in Live Donor Kidney Transplant Recipients on Postoperative Day 1 Does Not Increase the Incidence of Urine Leaks - Siskind, Eric; Sameyah, Emil; Goncharuk, Edwin; Olsen, Elizabeth M.; Feldman, Joshua; Giovinazzo, Katie; Blum, Mark; Tyrell, Richard; Evans, Cory; Kuncewitch, Michael; Alexander, Mohini; Israel, Ezra; Bhaskaran, Madhu; Calderon, Kellie; Jhaveri, Kenar D.; Sachdeva, Mala; Bellucci, Alessandro; Mattana, Joseph; Fishbane, Steven; D'Agostino, Catherine; Coppa, Gene; Molmenti, Ernesto
Catheterization of the urinary bladder during kidney transplantation is essential. The optimal time to remove the Foley catheter postoperatively is not universally defined. It is our practice to remove the Foley catheter on postoperative day 1 in live donor kidney transplant recipients who meet our standardized protocol criteria. We believe that early removal of Foley catheters increases patient comfort and mobility, decreases the risk of catheter associated urinary tract infections, and allows for decreased hospital length of stay. The hypothetical risk of early removal of Foley catheters would be the increased risk of urine leak. We reviewed 120 consecutive live...
Secretory Phospholipase A2 Is Associated with the Odds of Acute Coronary Syndromes through Elevation of Serum Amyloid-A Protein - Santoso, Anwar; Kaniawati, Marita; Bakri, Syakib; Yusuf, Irawan
In coronary heart disease (CHD), levels of secretory phospholipase A2 (sPLA2) are commonly increased. Serum amyloid-A (SAA) is increased in acute coronary syndromes (ACS) as well. It is needed to verify the hypotheses that sPLA2 is associated with the odds of ACS through elevation of SAA. We conducted a case–control study with 57 male patients with ACS and 30 controls matched by gender category. Levels of sPLA2, SAA, and myeloperoxidase (MPO) were measured by immunoreactive assay on the basis of a double-antibody sandwich technique. Levels of sPLA2, MPO, and SAA were significantly higher in patients than those in controls (11,359.0 ± 10,372.4...
Optimizing Cardiovascular Benefits of Exercise: A Review of Rodent Models - Davis, Brittany; Moriguchi, Takeshi; Sumpio, Bauer
Although research unanimously maintains that exercise can ward off cardiovascular disease (CVD), the optimal type, duration, intensity, and combination of forms are yet not clear. In our review of existing rodent-based studies on exercise and cardiovascular health, we attempt to find the optimal forms, intensities, and durations of exercise. Using Scopus and Medline, a literature review of English language comparative journal studies of cardiovascular benefits and exercise was performed. This review examines the existing literature on rodent models of aerobic, anaerobic, and power exercise and compares the benefits of various training forms, intensities, and durations. The rodent studies reviewed in...