Mostrando recursos 1 - 20 de 14.893

  1. High prevalence of Trichomonas gallinae in wild columbids across western and southern Europe

    Marx, Melanie; Reiner, Gerald; Willems, Hermann; Rocha, Gregorio; Hillerich, Klaus; Masello, Juan F.; Mayr, Sylvia L.; Moussa, Sarah; Dunn, Jenny C.; Thomas, Rebecca C.; Goodman, Simon J.; Hamer, Keith C.; Metzger, Benjamin; Cecere, Jacopo G.; Spina, Fernando; Koschkar, Steffen; Calderón, Luciano; Romeike, Tanja; Quillfeldt, Petra
    Background Avian trichomonosis is known as a widespread disease in columbids and passerines, and recent findings have highlighted the pathogenic character of some lineages found in wild birds. Trichomonosis can affect wild bird populations including endangered species, as has been shown for Mauritian pink pigeons Nesoenas mayeri in Mauritius and suggested for European turtle doves Streptopelia turtur in the UK. However, the disease trichomonosis is caused only by pathogenic lineages of the parasite Trichomonas gallinae. Therefore, understanding the prevalence and distribution of both potentially pathogenic and non-pathogenic T. gallinae lineages in turtle doves and other columbids across Europe is relevant to...

  2. Pragmatic and innovative inclusive exhibition design solutions through co-designing with blind and partially sighted visitors

    Chick, Anne
    This conference paper discusses the innovative and novel inclusive exhibition and service design solutions developed as part of a participatory action design research project. The solutions addressed enhancing the intellectual access of blind and partially sighted visitors to local and regional galleries and museums. This research was a collaboration between the National Centre for Craft & Design, RNIB, SENSE and Lincolnshire visually impaired people.

  3. Democracy, fascism, and the dissimulative affect of acceleration in social media

    Sutherland, Thomas
    ‘Can one democratize ubiquity, instantaneity, immediacy,’ Paul Virilio once enquired, given that these are ‘precisely the prerogatives of the divine – in other words, of autocracy?’ Indeed, the question of democratic politics, and their compatibility with the accelerative logics of contemporary capitalism, have never been so pressing. In this paper, I wish to argue that the primary affective experience of social media, focusing specifically upon the platform of Twitter, is of an accelerated becoming: a ceaseless stream of disparate data that furnishes us with the sense of a world changing at a pace to which we can never catch up....

  4. Beta-cyclodextrin (CD) inclusion complexes of disconnected synthetic cannabinoid molecules

    Bradbury, Ashley; Abdull Manap, Mohd Rashidi; Munshi, Tasnim; Scowen, Ian
    SERS has proven to be a powerful screening technique for synthetic cannabinoids. Research shows successful capping of silver nanoparticles with thiolated CDfor the detection of polycyclic aromatic hydrocarbons for SERS enhancement. CD is an oligosaccharide composed of seven α-D-glucopyranoside units and is commonly used in pharmaceuticals and drug delivery as its cavity can be used to form inclusion complexes with hydrophobic molecules.

  5. Simulation of causally dynamic hybrid bond graphs, with application to a power converter

    Margetts, Rebecca; Boudon, Benjamin; Ngwompo, Roger F.
    Causally dynamic hybrid bond graphs are generally considered unsuitable for simulation, and causality is therefore often constrained in hybrid bond graph models. This paper demonstrates how a causally dynamic model can be simulated, using a buck converter as a case study. A causally dynamic hybrid bond graph (utilizing controlled junctions) is used to derive a mixed-Boolean state equation. This state equation is transferred toMATLABR , where a simple routine assigns values to the Boolean parameters and then solves the model. Where storage elements are in dynamic causality, the model takes descriptor state form and an implicit solver is used. Solver...

  6. Food containing biotin and other B vitamins

    Marsh, Katrina A.; Watson, Timothy D. G.
    The present invention relates to a non-human diet or a non-human foodstuff comprising biotin at a concentration of at least 0.2 mg/400 kcal and/or one or more other B vitamins at a concentration of at least 33.0 mg/400 kcal, to a dietary supplement which, in addition to other nutrient intake supplies biotin at a concentration of at least 0.2 mg/400 kcal and/or one or more B other vitamins at a concentration of at least 33.0 mg/400 kcal. In combination the concentration of biotin and one more other B vitamins is at least 33.2 mg/400 kcal. The present invention also relates...

  7. Edible composition containing zinc and linoleic acid

    Marsh, Katrina A.; Watson, Timothy D. G.
    The present invention relates to a diet or foodstuff and a dietary supplement comprizing zinc at a concentration of above 28 mg/400 kcal and linoleic acid at a concentration of at least 4g/400 kcal or zinc at a concentration of 20 mg/400 kcal or above and linoleic acid at a concentration of 6 g/400 kcal or above. The diet/foodstuff and dietary supplement are useful in enhancing and/or improving the skin and coat condition of an animal. The present invention also relates to the use of the diet/foodstuff and dietary supplement in enhancing and/or improving the skin and coat composition of...

  8. What Is an attractive body? Using an interactive 3D program to create the ideal body for you and your partner

    Crossley, Kara L.; Cornelissen, Piers L.; Tovee, Martin J.
    What is the ideal body size and shape that we want for ourselves and our partners? What are the important physical features in this ideal? And do both genders agree on what is an attractive body? To answer these questions we used a 3D interactive software system which allows our participants to produce a photorealistic, virtual male or female body. Forty female and forty male heterosexual Caucasian observers (females mean age 19.10 years, s.d. 1.01; 40 males mean age 19.84, s.d. 1.66) set their own ideal size and shape, and the size and shape of their ideal partner using the...

  9. Perceptions of female body size and shape in China, Hong Kong, and the United Kingdom

    Mo, Josephine J. Y.; Cheung, Kate W. K.; Gledhill, Lucinda J.; Pollet, Thomas V.; Boothroyd, Lynda G.; Tovee, Martin J.
    Photographs of 50 women were rated for attractiveness, health, and fertility recorded by four sets of participants-Rural-Chinese (n = 50), Chinese participants in Hong Kong (n = 50), Chinese participants living in the United Kingdom (n = 50), and participants self-identifying as "Caucasian" living in the United Kingdom. The results suggest that a polynomial function of Body Mass Index (kg/m2) is the best predictor of all three judgments in all four observer groups. In contrast, shape cues, such as the waist-to-hip ratio (WHR), seem to play a relatively small role. Shape cues do consistently account for a greater proportion of...

  10. The BRIC puzzle: the impact of corruption, political instability and democratic accountability on stock market returns

    Lakshmi, Geeta; Saha, Shrabani
    .

  11. Robot education peers in a situated primary school study: personalisation promotes child learning

    Baxter, Paul; Ashurst, Emily; Read, Robin; Kennedy, James; Belpaeme, Tony
    The benefit of social robots to support child learning in an educational context over an extended period of time is evaluated. Specifically, the effect of personalisation and adaptation of robot social behaviour is assessed. Two autonomous robots were embedded within two matched classrooms of a primary school for a continuous two week period without experimenter supervision to act as learning companions for the children for familiar and novel subjects. Results suggest that while children in both personalised and non-personalised conditions learned, there was increased child learning of a novel subject exhibited when interacting with a robot that personalised its behaviours,...

  12. The Power of Partnerships: using data collaboratively to enhance the student experience

    Parkin, Emily; Harvey, Lilly; Barnes, Jennifer; Ayling, Angus
    This session will cover how the process of gathering and using feedback is delivered in partnership, and the different roles taken by the SU and University. It also discusses the importance of mobilising our Reps to take ownership of turnout in their areas, encouraging them to understand their importance to the research process, and empowering them as significant partners (for the SU and University) in enriching the student voice.

  13. Students Consulting on Teaching and technology enhanced learning

    Parkin, Emily; Harvey, Lilly; Ayling, Angus; Hatton, Jake
    The University of Lincoln supports students to be active partners in enhancing teaching and learning practice. This workshop will provide some examples of student partners helping to enhance the student experience, including Students Consulting on Teaching, and also give insight from students’ perspectives of the benefits and barriers to engaging in this way. Delegates will then be supported to explore potential opportunities to try something similar in their areas.

  14. Single cell calcium imaging

    Marsh, Katrina A.
    As our understanding of the biological sciences expands, the boundaries between traditional disciplines tend to blur at the edges. Physiologists and pharmacologists, for instance, now need to embrace techniques that until recently were the strict preserves of biochemists and molecular biologists. However, the acquisition of new technologies can be a time-consuming and frustrating business, and unless an expert is on hand to give instruction, precious hours can be spent poring over half-described Methods sections with no guarantee of eventual success. The aim of Signal Transduction Protocols has been to get experts with "hands-on" experience in particular techniques to give detailed...

  15. Optimising skin and coat condition in the dog

    LLoyd, David H.; Marsh, Katrina A
    .

  16. Expression of muscarinic M sub 3 -receptors coupled to inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells

    Harriss, D. R.; Marsh, K. A.; Birmingham, A. T.; Hill, S. J.
    Purpose To investigate the effect of muscarinic receptor agonists and antagonists on the accumulation of inositol phosphates in cultures of human detrusor smooth muscle cells. Materials and Methods Primary explant culture was used to derive smooth muscle cell lines from small bladder biopsies. The cells were loaded with [sup 3 H]-myoinositol, stimulated with muscarinic agonists, and the accumulation of [sup 3 H]-inositol phosphates was measured by liquid scintillation counting. Results Carbachol (EC50 8.3 micromolar), methacholine (EC50, 7.5 micromolar), oxotremorine (EC50 2.5 micromolar) and pilocarpine (EC sub 50 8.3 micromolar) produced concentration-dependent rises in the accumulation of total [sup 3 H]-inositol phosphates. M1 (pirenzepine), M sub...

  17. Receptor-stimulated phospholipase C activity in human umbilical artery cultured endothelial cells grown in a low oxygen environment

    Marsh, K. A.; Draper, L .M.; Rubin, P. C.; Hill, S. J.
    Endothelial cells of the human umbilical blood vessels are widely cultured in an oxygen tension (21%) far above that in which they exist in vivo (3%). This study investigates the effect of the long term culture (ca. 1 month) of human umbilical artery endothelial cells in a reduced oxygen environment (3%: HUAEC3) in comparison to cells grown in a ‘normoxic’ environment (21%: HUAEC21). Despite reports of altered metabolic pathways and reduced membrane integrity in other cell types, the characteristics of HUAEC3 were found to be similar to those of HUAEC21 with respect to morphology, immunocytochemical profile and in vitro growth...

  18. Effects of zinc and linoleic acid supplementation on the skin and coat quality of dogs receiving a complete and balanced diet

    Marsh, K. A.; Ruedisueli, F. L.; Coe, S. L.; Watson, T. G. D.
    This study investigates what effect adding zinc to a final dietary concentration of 23.9 mg MJ−1 and/or linoleic acid to a dietary concentration of 3.6 g MJ−1 in a complete and balanced diet has on the skin and haircoat condition of adult dogs. All animals were fed for nine weeks on a standard diet followed by nine weeks on a supplemented diet. After each phase animals were quantitatively assessed with respect to the condition and function of their skin and coat. Dogs supplemented with the combination of zinc and linoleic acid showed a significant improvement in coat gloss (P =...

  19. Isolation and characterization of multiple cell types from a single human colonic carcinoma: Tumourigenicity of these cell types in a xenograft system

    Marsh, Katrina A.; Stamp, Gordon W. H.; Kirkland, Susan C.
    The HCA-7 cell line was established from a moderately well differentiated mucinous adenocarcinoma of the colon, which showed histological heterogeneity. This was reflected in the morphological heterogeneity in early passages of the HCA-7 cell line but diminished as the cells were passaged in vitro. Nine subpopulations were isolated from early passage cultures of the HCA-7 line and maintained as cell lines. Each subpopulation demonstrated a unique set of stable biological characteristics in vitro. When established in vivo, there was a wide variation in xenograft generation time. The parent cell line gave rise to six distinct xenograft patterns, two of which...

  20. Desensitization of muscarinic receptor-coupled inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells

    Marsh, K. A.; Harriss, D. R.; Hill, S. J.
    PURPOSE: The aim of this study was to investigate the desensitization characteristics of muscarinic M3 receptors in primary cultures of human detrusor smooth muscle cells. MATERIALS AND METHODS: Cell cultures were prepared from cold cup pinch biopsies of the human detrusor muscles by explant culture methods. Accumulation of (3)H-inositol phosphates was measured on confluent monolayers as described previously in detail. Desensitization was achieved by pre-incubating the cells with carbachol or histamine for 5 to 60 minutes. RESULTS: Carbachol induced a concentration-dependent increase in phosphoinositide turnover in naive cells, the response being rapid and evident after only a 30-second exposure to...

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