Recursos de colección

Repositorio Institucional de la Universidad de Cordoba :: Spain (53.875 recursos)

El repositorio recoge todo tipo de materiales digitales: artículos de revistas, comunicaciones a congresos, tesis doctorales, documentos de trabajo, materiales docentes y objetos de aprendizaje, así como los productos digitales del patrimonio bibliográfico de la Universidad de Córdoba.

DGen-Artículos, capítulos...

Mostrando recursos 1 - 16 de 16

  1. ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion

    Roldán-Arjona, Teresa; Rodríguez Ariza, Rafael; Ponferrada-Marín, María Isabel
    Arabidopsis ROS1 belongs to a family of plant 5-methycytosine DNA glycosylases that initiate DNA demethylation through base excision. ROS1 displays the remarkable capacity to excise 5-meC, and to a lesser extent T, while retaining the ability to discriminate effectively against C and U. We found that replacement of the C5-methyl group by halogen substituents greatly decreased excision of the target base. Furthermore, 5-meC was excised more efficiently from mismatches, whereas excision of T only occurred when mispaired with G. These results suggest that ROS1 specificity arises by a combination of selective recognition at the active site and thermodynamic stability of the target base. We also found that ROS1 is a low-turnover catalyst because it binds...

  2. A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine

    Parrilla-Doblas, Jara; Roldán-Arjona, Teresa; Rodríguez Ariza, Rafael; Ponferrada-Marín, María Isabel
    DNA cytosine methylation (5-meC) is a widespread epigenetic mark associated to gene silencing. In plants, DEMETER-LIKE (DML) proteins typified by Arabidopsis REPRESSOR OF SILENCING 1 (ROS1) initiate active DNA demethylation by catalyzing 5-meC excision. DML proteins belong to the HhH-GPD superfamily, the largest and most functionally diverse group of DNA glycosylases, but the molecular properties that underlie their capacity to specifically recognize and excise 5-meC are largely unknown. We have found that sequence similarity to HhH-GPD enzymes in DML proteins is actually distributed over two non-contiguous segments connected by a predicted disordered region. We used homology-based modeling to locate candidate residues important for ROS1 function in both segments, and tested our predictions by site-specific mutagenesis. We found...

  3. Bases moleculares de la desmetilación de DNA en Arabidopsis thaliana

    Parrilla-Doblas, Jara; Roldán-Arjona, Teresa; Rodríguez Ariza, Rafael; Ponferrada-Marín, María Isabel
    Resumen de la comunicación presentada al XX Congreso de la Sociedad Española de Mutagénesis Ambiental – Córdoba 2012

  4. Frecuencias alélicas y genotípicas del gen PRNP en el núcleo de selección de la raza segureña

    León Jurado, J.M.; Delgado-Bermejo, J.V.; Martínez Martínez, Amparo; Tino, M.; Puntas, J.; Barba Capote, C.J.

  5. Evaluación genética de caracteres postmorten en el ovino segureño fundamentada en la calificación morfológica lineal

    Camacho Vallejo, M.E.; Delgado-Bermejo, J.V.; Puntas, J.; León Jurado, J.M.; Quiroz, J.; Barba Capote, C.J.

  6. Creación de un Banco de Germoplasma en la Raza Bovina Marismeña como base para su conservación

    Vallecillo, A.; Mayorga, F.; Camacho Vallejo, M.E.; Delgado-Bermejo, J.V.; Cabello, A.; Quiroz, J.; Wanderley, C.

  7. El programa de mejora genética en la Agrupación Caprina Canaria

    Rodríguez, J.L.; Delgado-Bermejo, J.V.; Barba Capote, C.J.

  8. Biodiversidad caprina en España

    Vidal, O.; Gómez, M.; Manunza, A.; Amills, M.; Martín, D.; Ferrando, A.; Jordana, J.; Pons, A.; Delgado-Bermejo, J.V.; Landi, Vincenzo; Capote, J.F.
    Goats are located predominantly in the dry Spain specially in Andalusia, Castilla-La Mancha, the Canary Islands, Murcia and Extremadura. In this paper we have analyzed 867 samples of 18 Spanish goat populations from different parts of the Iberian Peninsula (Azpi-Gorri, Blanca de Rasquera, Blanca Andaluza, Blanca Celtibérica, Florida, Malagueña, Murciano-Granadina, Negra Serrana, Payoya and Retinta) and the Balearic (Ibicenca, Mallorquina and Formentera goat) and Canarian Archipelagos (Ajuí, Majorera, Palmera, Tenerife North and Tenerife South). Twenty-three microsatellites have been amplified and the within-breed genetic variation has been calculated through the analysis of the mean number of alleles, heterozygosity and FIS The...

  9. AXA: un programa de ordenador para la gestión de los núcleos de control lechero en la Agrupación Caprina Canaria

    Molina Alcalá, Antonio; Delgado-Bermejo, J.V.; Delgado Romero, F.; Fresno Baquero, M.R.; Camacho Vallejo, M.E.; Darmanin, N.; Capote, J.F.
    A computer program, developed in Clipper, for the management of the genealogical and productive information from the Canary Goat Group, is described. The two first sections of this program are planned for the males and females genealogical data arrangement. Third section is devised for the productive data storage. Fourth section is constructed for the emission of reports and finally, fifth section is a miscellaneous of utilities, where the connection with other programs must be highlighted. Also an exit control is enclosed. The basic purposes of this program aim the emission of official production reports for the Administration and farmers, and...

  10. Morfoaxa: un programa informático para la valoración morfológica del caprino lechero: aplicación a la agrupación caprina canaria

    Delgado, F.; Delgado-Bermejo, J.V.; Camacho Vallejo, M.E.; Fresno Baquero, M.R.; Molina Alcalá, Antonio; Capote, J.F.
    An assistant computer program for the morphologic evaluation of the Canary Dairy Goat is described. This is presented in two versions, the first one for its apLication in stable, the second one for the competitive evaluation in exhibitions. With this program the evaluation rapidity increases, the information flows towards the central database is enhanced, the punctuation is objectived, and also it collaborates with the homogeneisation of the evaluation criteria.

  11. Preliminary study of the Majorera milk goat productive performance

    Gómez, J.; Delgado-Bermejo, J.V.; Molina Alcalá, Antonio; Fresno Baquero, M.R.; Darmanin, N.; Capote, J.F.
    In the present paper we have made an evaluation of the milking and reproductive aptitudes of the Majorera Goat with a view to the productive characterization and definition of these animals, all from the Fuerteventura"s Milking Control programme. In this study 452 animals have participated, belonging to 7 of the most representative farms on the island. With respect to the reproductive aptitude. we have found interesting values of 1-95±0,03 of mean prolificily; with an oulstanding of 56.2 p.100 of double kidding, and only 4-6 p.100 abortions. Among farms the prolificity values oscillate between 1.73±0,07 and 2-09±0,08. The descriptive statistics control...

  12. The Palmera Goat (video)

    López, J.L.; Delgado-Bermejo, J.V.; Fresno Baquero, M.R.; Capote, J.F.
    Recent investigations have shown that within the Canary Caprine Group, the Palmera Goat is which most differs in morphological and productive aspects. This video, shows the characteristics of the Palmera goat and the present management systems which include similar custom to those developed in the prehispanic age when goats constitute the essential basis of the native economy.

  13. Sensitization for the autochthonous breeds conservation via the public shows of animals

    Delgado-Bermejo, J.V.; Fresno Baquero, M.R.; Camacho Vallejo, M.E.; Molina Alcalá, Antonio; Burgos, A.; Darmanin, N.; Capote, J.F.
    From a inquiry about conservation of rare breeds answered by the visitors to the Autochthonous Domestic Animal Breeds Public Show Agrocanarias 90, we evaluate its sensitization power on people of different age and relationship with the land. We also expose some interesting suggestions made by those questioned.

  14. The canary islands breeds: past, present and future

    Camacho Vallejo, M.E.; Delgado-Bermejo, J.V.; Fresno Baquero, M.R.; Darmanin, N.; Capote, J.F.
    We describe the means developed by official and private institutions for the conservation of Canary Breeds. We evaluate the response to concrete actions comparing the evolution of their census with presented at the Warwick Conference (1989).

  15. Estudio para la caracterización de la raza ovina Palmera

    Delgado-Bermejo, J.V.; Fresno Baquero, M.R.; Álvarez, S.; Barba Capote, C.J.; Capote, J.F.
    The Palmera sheep breed is officially registered in the Spanish Breeds Catalogue in 1997, as autoctonus breed with a special protection. The census in 1996 was not above 150 animals (82 females, 6 males and 60 animals under 12 months). In order to the census we can affirm the critical situation of the breed in serious extinction danger. In this study we try to define its racial patron serving as a base for its recuperation and conservation. A sample of 64 adult animals (60 females and 4 males) was studied, describing its morphology and faneroptic characters an studying its zoometric...

  16. Estudio para la caracterización de la raza ovina canaria

    Delgado-Bermejo, J.V.; Fresno Baquero, M.R.; Álvarez, S.; Barba Capote, C.J.; Capote, J.F.
    The sheep census of the Canary Islands is about 43.000 animals, of this the Canarian Sheep Breed is above 90 percent. It presents a great interest for obtaining milk and meat as quality products. Attending exclusively to the census, there is no problem of conservation, but this breed is affected by hybridisation process, overcoat in Tenerife. Here we present a study about the breed characterisation, analysing descriptive parameters as morphometric and faneroptic, and zoometric parameters of 168 animals (156 females and 12 males) in La Palma and Tenerife.

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