Mostrando recursos 1 - 10 de 10

  1. Proprioceptive deficits in Parkinson’s disease : from clinical data to animal experimentation

    Santos, Letícia Ribeiro da Silva dos; Souza, Tadeu Mello e; Araujo, Lisiane Bizarro; Oliveira Junior, Alcyr Alves de
    Parkinson’s disease (PD) is characterized by the manifestation of akinesia, slowness to initiate movement, muscle rigidity, and tremors. However, recent evidence indicates that this pathology also causes alterations in proprioception. Disturbances in proprioceptive mechanisms directly affect postural control and the ability to calculate the velocity and amplitude of movement, suggesting that these alterations are related to the motor symptoms of PD. This article reviews the clinical data on these symptoms and presents evidence of a connection between proprioceptive deficits and the physiology of PD. The identification of proprioceptive impairments in different forms of Parkinsonism can provide valuable clues on the...

  2. Proprioceptive deficits in Parkinson’s disease : from clinical data to animal experimentation

    Santos, Letícia Ribeiro da Silva dos; Souza, Tadeu Mello e; Araujo, Lisiane Bizarro; Oliveira Junior, Alcyr Alves de
    Parkinson’s disease (PD) is characterized by the manifestation of akinesia, slowness to initiate movement, muscle rigidity, and tremors. However, recent evidence indicates that this pathology also causes alterations in proprioception. Disturbances in proprioceptive mechanisms directly affect postural control and the ability to calculate the velocity and amplitude of movement, suggesting that these alterations are related to the motor symptoms of PD. This article reviews the clinical data on these symptoms and presents evidence of a connection between proprioceptive deficits and the physiology of PD. The identification of proprioceptive impairments in different forms of Parkinsonism can provide valuable clues on the...

  3. Access to treatment for phenylketonuria by judicial means in Rio Grande do Sul, Brazil


    Treatment of phenylketonuria (PKU) includes the use of a metabolic formula which should be provided free of charge by the Unified Health System (SUS). This retrospective, observational study sought to characterize judicial channels to obtain PKU treatment in Rio Grande do Sul (RS), Brazil. Lawsuits filed between 2001– 2010 and having as beneficiaries PKU patients requesting treatment for the disease were included. Of 20 lawsuits filed, corresponding to 16.8% of RS patients with PKU, 19 were retrieved for analysis. Of these, only two sought to obtain therapies other than metabolic formula. In all the other 17 cases, prior treatment requests...

  4. The seed bank of subtropical grasslands withcontrasting land-use history in southern Brazil

    Vieira, Mariana de Souza; Bonilha, Camila Leal; Boldrini, Ilsi Iob; Overbeck, Gerhard Ernst
    The expansion of land use for agriculture is among the main reasons for the reduction of natural grasslands around the world, and little is known about the recovery potential of original native grassland vegetation from seed banks. The aim of this study was to assess the seed bank potential of grassland areas with or without history of cultivation in southern Brazil. Specifically, we aimed at evaluating if agricultural use allowed for the persistence of species typical of natural grasslands in soil seed banks. We analyzed seed banks in two areas with a history of cultivation and in two natural grasslands....

  5. Mandibular condylar hyperplasia : diagnosis and management. Case report

    Pinto, Isabel; Fonseca, Júlio; Vinagre, Alexandra; Ângelo, David; Sanz, David; Grossmann, Eduardo
    BACKGROUND AND OBJECTIVES: Mandibular condylar hyperplasia is a disease where excessive growth of mandibular condyle, ramus and body elicits facial asymmetry. Its therapeutic management is not a consensus and, due to its complexity, is a challenge for maxillofacial surgeons and orthodontists. This study aimed at discussing clinical, diagnostic and therapeutic aspects of the management of this disease, and at explaining the role of condylectomy. CASE REPORT: Female patient, 19 years old, Caucasian, looked for maxillofacial surgeon assistance due to facial asymmetry and pain on right temporomandibular joint. Patient had no medical, gestational or family history of facial deformity, or history...

  6. Cognition and functioning in bipolar depression

    Kapczinski, Natalia Soncini; Narvaez, Joana Corrêa de Magalhães; Magalhães, Pedro Vieira da Silva; Bücker, Joana; Peuker, Ana Carolina Wolf Baldino; Loredo, Ana C.; Troiano, Federico; Czepielewski, Letícia Sanguinetti; Rosa, Adriane Ribeiro; Fries, Gabriel Rodrigo; Gama, Clarissa Severino
    Objectives: Depressive symptoms are associated with worse outcomes in patients with bipolar disorder (BD). However, scarce data are available regarding neurocognitive profiles across different areas of functioning among BD patients with moderate and severe depression. Our objective was to assess cognition and global functioning in a group of patients with bipolar depression. Methods: Data were available for 100 patients with bipolar depression (78% female) and 70 controls (64% female) paired by age and education level. Cognitive function was assessed with a neuropsychological test battery. Functioning was assessed with the Functioning Assessment Short Test. Results: In patients, severe depression was associated...

  7. Shortened telomere length in bipolar disorder : a comparison of the early and late stages of disease

    Barbé-Tuana, Florencia María; Parisi, Mariana Migliorini; Panizzutti, Bruna Schilling; Fries, Gabriel Rodrigo; Grun, Lucas Kich; Guma, Fátima Theresinha Costa Rodrigues; Kapczinski, Flávio Pereira; Berk, Michael; Gama, Clarissa Severino; Rosa, Adriane Ribeiro
    Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, such as type II diabetes, metabolic syndrome, osteoporosis, and cardiovascular disorders. Several biological findings have been associated with age-related disorders, including increased oxidative stress, inflammation, and telomere shortening. The objective of this study was to compare telomere length among participants with BD at early and late stages and age- and gender-matched healthy controls. Methods: Twenty-six euthymic subjects with BD and 34 healthy controls were recruited. Genomic DNA was extracted from peripheral blood and mean telomere length was measured using real-time quantitative polymerase chain reaction. Results: Telomere length...

  8. Internacionalização da produção científica brasileira : políticas, estratégias e medidas de avaliação

    Santin, Dirce Maria; Vanz, Samile Andrea de Souza; Stumpf, Ida Regina Chitto
    A internacionalização da produção científica tem reflexos significativos na ciência contemporânea e na inserção internacional dos países em desenvolvimento. Apesar dos esforços empreendidos pelo Brasil nas últimas décadas, a produção científica nacional ainda enfrenta entraves em relação ao alcance e ao impacto internacional das publicações. Este artigo aborda as políticas e as estratégias voltadas à internacionalização da produção científica brasileira e apresenta algumas medidas de avaliação. A internacionalização da produção é discutida com base nos aspectos difusão, colaboração e impacto internacional, com vistas a refletir sobre as possibilidades de ampliar a projeção da ciência brasileira no meio científico internacional.

  9. As duas epistemes de Balduíno Rambo

    Araujo, Aldo Mellender de

  10. The effects of constant and alternating temperatures on the reproductive potential, life span, and life expectancy of Anastrepha fraterculus (Wiedemann) (Diptera: Tephritidae)

    Cardoso, Valesca Veiga; Ferreira, Melissa Prietto; Montagner, Juliana de Moura; Garcia Fernandez, Casimiro; Moreira, Jose Claudio Fonseca; Oliveira, Alice Kalisz de
    O desenvolvimento ovariano, ovoposição, eclosão larval, atividade de ornitina descarboxilase (ODC), medidas de largura, comprimento e área do ovário, testículo e apódema ejaculatório e número de espermatozóides de Anastrepha fraterculus (Wiedemann) foram analisados em temperaturas alternadas (20º/6oC e 20º/13oC) e constantes (6oC e 25oC). A longevidade e a expectativa de vida também foram analisadas em ambos os sexos. Todos os resultados sugerem que a temperatura baixa e principalmente as temperaturas alternadas afetam não somente o potencial reprodutivo de machos e fêmeas, mas também sua longevidade e expectativa de vida, prolongando-as. Essas mudanças podem ser uma poderosa estratégia usada por A....

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.