Mostrando recursos 1 - 20 de 140

  1. Prognostic factors for recurrence of a first seizure during childhood

    Winckler, Maria Isabel Bragatti; Rotta, Newra Tellechea
    This study was designed with the objective of evaluating the chance of recurrence in our area and to answer questions regarding prognostic factors capable of helping in the management of the first seizure in childhood. One hundred and thirty six children from 1 month to 12 years of age seen at the Pediatric Emergency Division of Hospital de Clínicas de Porto Alegre because of a first seizure with or without triggering factors were inclued in the study. The follow-up included 121 children. We concluded that family history of seizures, presence of triggering factors at first event, seizure type, seizure duration...

  2. Prognostic factors for recurrence of a first seizure during childhood

    Winckler, Maria Isabel Bragatti; Rotta, Newra Tellechea
    This study was designed with the objective of evaluating the chance of recurrence in our area and to answer questions regarding prognostic factors capable of helping in the management of the first seizure in childhood. One hundred and thirty six children from 1 month to 12 years of age seen at the Pediatric Emergency Division of Hospital de Clínicas de Porto Alegre because of a first seizure with or without triggering factors were inclued in the study. The follow-up included 121 children. We concluded that family history of seizures, presence of triggering factors at first event, seizure type, seizure duration...

  3. Encefalopatia induzida por cefepime : achados clínicos e eletroencefalográficos em sete pacientes

    Bragatti, José Augusto; Rossato, Roberto; Ziomkowki, Sofia Cláudia; Kliemann, Frederico Arthur Dahne
    Cefepime, uma cefalosporina de quarta geração, com amplo espectro de ação, é um antibiótico largamente utilizado no tratamento de infecções graves em ambientes hospitalares. O registro de segurança deste fármaco é considerado favorável. Vários casos de encefalopatia grave, associada ao uso de cefepime, reversível, foram descritosrecentemente. Nopresente artigo, descrevemos sete casos de encefalopatia induzida por cefepime, com achados eletroencefalográficos(EEG) característicos, que apresentaram reversão do quadro com a suspensão da droga. As relações do padrão EEG encontrado nestes pacientes com estado epiléptico não-convulsivo são consideradas, bem como a possibilidade de enquadrar os pacientes estudados na entidade “encefalopatia epileptiforme”.

  4. Encefalopatia induzida por cefepime : achados clínicos e eletroencefalográficos em sete pacientes

    Bragatti, José Augusto; Rossato, Roberto; Ziomkowki, Sofia Cláudia; Kliemann, Frederico Arthur Dahne
    Cefepime, uma cefalosporina de quarta geração, com amplo espectro de ação, é um antibiótico largamente utilizado no tratamento de infecções graves em ambientes hospitalares. O registro de segurança deste fármaco é considerado favorável. Vários casos de encefalopatia grave, associada ao uso de cefepime, reversível, foram descritosrecentemente. Nopresente artigo, descrevemos sete casos de encefalopatia induzida por cefepime, com achados eletroencefalográficos(EEG) característicos, que apresentaram reversão do quadro com a suspensão da droga. As relações do padrão EEG encontrado nestes pacientes com estado epiléptico não-convulsivo são consideradas, bem como a possibilidade de enquadrar os pacientes estudados na entidade “encefalopatia epileptiforme”.

  5. Hormônios tireóideos na sintomatologia de doenças neuropsiquiátricas : a propósito de um caso

    Winckler, Maria Isabel Bragatti; Rotta, Newra Tellechea
    A etiologia das doenças neuropsiquiátricas suporta múltiplos enfoques. Dentre eles, o papel dos hormônios tireóideos tem sido destacado atualmente. Os autores registram o caso de um menino de cinco anos de idade com hipotireoidismo congênito associado a problemas do desenvolvimento de ordem instrumental e estrutural, que se caracterizavam por retardo no desenvolvimento neuropsicomotor, principalmente na fala, hipotonia muscular, e hipoacusia bilateral. Tecem considerações sobre o papel do controle hormonal na melhora da sintomatologia, principalmente quanto à atenção e atividade psicomotora.

  6. Hormônios tireóideos na sintomatologia de doenças neuropsiquiátricas : a propósito de um caso

    Winckler, Maria Isabel Bragatti; Rotta, Newra Tellechea
    A etiologia das doenças neuropsiquiátricas suporta múltiplos enfoques. Dentre eles, o papel dos hormônios tireóideos tem sido destacado atualmente. Os autores registram o caso de um menino de cinco anos de idade com hipotireoidismo congênito associado a problemas do desenvolvimento de ordem instrumental e estrutural, que se caracterizavam por retardo no desenvolvimento neuropsicomotor, principalmente na fala, hipotonia muscular, e hipoacusia bilateral. Tecem considerações sobre o papel do controle hormonal na melhora da sintomatologia, principalmente quanto à atenção e atividade psicomotora.

  7. Neuropsychiatric symptoms as the main determinant of caregiver burden in Alzheimer’s disease

    Kochhann, Renata; Borba, Ericksen Mielle; Cerveira, Maria Otilia; Onyszko, Diego Cristiano; Jesus, Alyne Gonçalves de; Forster, Leticia M.K.; Carthery-Goulart, Maria Teresa; chaves,luisa; Godinho, Claudia da Cunha; Pádua, Analuiza Camozzato de; Chaves, Marcia Lorena Fagundes
    Caregiver burden is common in Alzheimer’s disease (AD), decreasing the quality of life among caregivers and patients. Projections of aging and aging-related diseases such as AD in developing countries justify additional data about this issue because people living in these countries have shown similarly high levels of caregiver strain as in the developed world. Objective: The aim of this study was to analyze the association of AD caregivers’ burden with patients’ neuropsychiatric symptoms (NPS), cognitive status, severity of dementia, functional capacity, caregiver sociodemographic characteristics, and the characteristics of care provided by caregivers. Methods: A cross-sectional study was conducted in a...

  8. Neuropsychiatric symptoms as the main determinant of caregiver burden in Alzheimer’s disease

    Kochhann, Renata; Borba, Ericksen Mielle; Cerveira, Maria Otilia; Onyszko, Diego Cristiano; Jesus, Alyne Gonçalves de; Forster, Leticia M.K.; Carthery-Goulart, Maria Teresa; chaves,luisa; Godinho, Claudia da Cunha; Pádua, Analuiza Camozzato de; Chaves, Marcia Lorena Fagundes
    Caregiver burden is common in Alzheimer’s disease (AD), decreasing the quality of life among caregivers and patients. Projections of aging and aging-related diseases such as AD in developing countries justify additional data about this issue because people living in these countries have shown similarly high levels of caregiver strain as in the developed world. Objective: The aim of this study was to analyze the association of AD caregivers’ burden with patients’ neuropsychiatric symptoms (NPS), cognitive status, severity of dementia, functional capacity, caregiver sociodemographic characteristics, and the characteristics of care provided by caregivers. Methods: A cross-sectional study was conducted in a...

  9. Effects of galantamine and galantamine combined with nimodipine on cognitive speed and quality of life in mixed dementia : a 24- week, randomized, placebo-controlled exploratory trial (the REMIX study)

    Caramelli, Paulo; Laks, Jerson; Palmini, André Luis Fernandes; Nitrini, Ricardo; Chaves, Marcia Lorena Fagundes; Forlenza, Orestes Vicente; Vale, Francisco de Assis Carvalho do; Barbosa, Maira Tonidandel; Bottino, Cássio Machado de Campos; Machado, João Carlos (Medicina); Charchat, Helenice; Lawson, Fabio Lorea
    The effects of galantamine (GAL) on quality of life (QoL) and cognitive speed, as well its effects combined with nimodipine (NIM) in Alzheimer disease (AD) with cerebrovascular disease (mixed dementia), have not been explored. Method: Double-blind, placebo-controlled, multicenter Brazilian trial, studying the effects of GAL/NIM vs. GAL/placebo (PLA) in mild to moderate mixed dementia. Patients were randomized to receive GAL/NIM or GAL/PLA for 24 weeks. Primary efficacy measures were changes on a computerized neuropsychological battery (CNTB) and QoL Scale in Alzheimer’s Disease (QoL-AD) from baseline to week 24. Results: Twenty-one patients received at least one drug dose (9 GAL/NIM and...

  10. Effects of galantamine and galantamine combined with nimodipine on cognitive speed and quality of life in mixed dementia : a 24- week, randomized, placebo-controlled exploratory trial (the REMIX study)

    Caramelli, Paulo; Laks, Jerson; Palmini, André Luis Fernandes; Nitrini, Ricardo; Chaves, Marcia Lorena Fagundes; Forlenza, Orestes Vicente; Vale, Francisco de Assis Carvalho do; Barbosa, Maira Tonidandel; Bottino, Cássio Machado de Campos; Machado, João Carlos (Medicina); Charchat, Helenice; Lawson, Fabio Lorea
    The effects of galantamine (GAL) on quality of life (QoL) and cognitive speed, as well its effects combined with nimodipine (NIM) in Alzheimer disease (AD) with cerebrovascular disease (mixed dementia), have not been explored. Method: Double-blind, placebo-controlled, multicenter Brazilian trial, studying the effects of GAL/NIM vs. GAL/placebo (PLA) in mild to moderate mixed dementia. Patients were randomized to receive GAL/NIM or GAL/PLA for 24 weeks. Primary efficacy measures were changes on a computerized neuropsychological battery (CNTB) and QoL Scale in Alzheimer’s Disease (QoL-AD) from baseline to week 24. Results: Twenty-one patients received at least one drug dose (9 GAL/NIM and...

  11. In vivo and in vitro evaluation of the efficacy of a peracetic acid-based disinfectant for decontamination of acrylic resins

    Chassot, Ana Lucia Campani; Poisl, Maria Ines Pereira; Samuel, Susana Maria Werner
    The purpose of this study was to assess the antimicrobial efficacy of a peracetic acid-based disinfectant for decontamination of heatpolymerized, chemically activated and microwave-polymerized acrylic resins. Resin plates were contaminated in vivo upon intraoral use by 10 volunteers for 7 nights and slabs were contaminated in vitro by contact with Bacillus subtilis and Bacillus stearothermophilus. The contaminated acrylic resin specimens were immersed in a 0.2% peracetic acid-based disinfectant (Sterilife®; Lifemed) for 5 min or 10 min and placed in a BHI culture medium. After incubation at 37°C for 48 h, bacterial growth was assessed by analyzing turbidity of the medium....

  12. In vivo and in vitro evaluation of the efficacy of a peracetic acid-based disinfectant for decontamination of acrylic resins

    Chassot, Ana Lucia Campani; Poisl, Maria Ines Pereira; Samuel, Susana Maria Werner
    The purpose of this study was to assess the antimicrobial efficacy of a peracetic acid-based disinfectant for decontamination of heatpolymerized, chemically activated and microwave-polymerized acrylic resins. Resin plates were contaminated in vivo upon intraoral use by 10 volunteers for 7 nights and slabs were contaminated in vitro by contact with Bacillus subtilis and Bacillus stearothermophilus. The contaminated acrylic resin specimens were immersed in a 0.2% peracetic acid-based disinfectant (Sterilife®; Lifemed) for 5 min or 10 min and placed in a BHI culture medium. After incubation at 37°C for 48 h, bacterial growth was assessed by analyzing turbidity of the medium....

  13. Ehrlichiosis in Brazil

    Vieira, Rafael Felipe da Costa; Biondo, Alexander Welker; Guimarães, Ana Marcia Sá; Santos, Andrea Pires dos; Santos, Rodrigo Pires dos; Dutra, Leonardo Hermes; Diniz, Pedro Paulo Vissotto de Paiva; Morais, Helio Autran de; Messick, Joanne Belle; Labruna, Marcelo Bahia; Vidotto, Odilon
    Ehrlichiosis is a disease caused by rickettsial organisms belonging to the genus Ehrlichia. In Brazil, molecular and serological studies have evaluated the occurrence of Ehrlichia species in dogs, cats, wild animals and humans. Ehrlichia canis is the main species found in dogs in Brazil, although E. ewingii infection has been recently suspected in five dogs. Ehrlichia chaffeensis DNA has been detected and characterized in mash deer, whereas E. muris and E. ruminantium have not yet been identified in Brazil. Canine monocytic ehrlichiosis caused by E. canis appears to be highly endemic in several regions of Brazil, however prevalence data are...

  14. Ehrlichiosis in Brazil

    Vieira, Rafael Felipe da Costa; Biondo, Alexander Welker; Guimarães, Ana Marcia Sá; Santos, Andrea Pires dos; Santos, Rodrigo Pires dos; Dutra, Leonardo Hermes; Diniz, Pedro Paulo Vissotto de Paiva; Morais, Helio Autran de; Messick, Joanne Belle; Labruna, Marcelo Bahia; Vidotto, Odilon
    Ehrlichiosis is a disease caused by rickettsial organisms belonging to the genus Ehrlichia. In Brazil, molecular and serological studies have evaluated the occurrence of Ehrlichia species in dogs, cats, wild animals and humans. Ehrlichia canis is the main species found in dogs in Brazil, although E. ewingii infection has been recently suspected in five dogs. Ehrlichia chaffeensis DNA has been detected and characterized in mash deer, whereas E. muris and E. ruminantium have not yet been identified in Brazil. Canine monocytic ehrlichiosis caused by E. canis appears to be highly endemic in several regions of Brazil, however prevalence data are...

  15. Promising treatments for neuropathic pain

    Schestatsky, Pedro; Vidor, Liliane Pinto; Winckler, Pablo Brea; Araújo, Tatiane Gomes de; Caumo, Wolnei
    In the last few years the understanding of mechanisms and, consequently, the diagnosis of neuropathic pain (NP) has becoming progressively clearer in clinical practice. However, the treatment of such condition remains challenging so far. One of the reasons for such difficulty is the diversity of mechanisms involved in NP generation and its persistency. In the present review we discuss several treatment modalities for NP that are scantily applied in daily clinical practice. For that, we collected positive clinical evidence of unusual and SECS (Safe, Easy, Cheap, and Sensible) approaches for NP. The aim of this review is not to establish...

  16. Promising treatments for neuropathic pain

    Schestatsky, Pedro; Vidor, Liliane Pinto; Winckler, Pablo Brea; Araújo, Tatiane Gomes de; Caumo, Wolnei
    In the last few years the understanding of mechanisms and, consequently, the diagnosis of neuropathic pain (NP) has becoming progressively clearer in clinical practice. However, the treatment of such condition remains challenging so far. One of the reasons for such difficulty is the diversity of mechanisms involved in NP generation and its persistency. In the present review we discuss several treatment modalities for NP that are scantily applied in daily clinical practice. For that, we collected positive clinical evidence of unusual and SECS (Safe, Easy, Cheap, and Sensible) approaches for NP. The aim of this review is not to establish...

  17. Influence of peracetic acid at acrylic resin properties

    Hehn, Lisiane; Macedo, Érika de Oliveira Dias de; Collares, Fabrício Mezzomo; Leitune, Vicente Castelo Branco; Samuel, Susana Maria Werner
    Purpose: To evaluate the influence of peracetic acid immersion on water sorption, solubility and microhardness of heat and self-cured acrylic resins. Methods: Thirty specimens of each type of acrylic resin were produced for sorption, solubility and microhardness evaluation. Sorption and solubility were evaluated based on ISO1567. For the microhardness test, specimens (20.0×5.0×10.0 mm) were made and evaluated under a 100g load for 15 s. The test groups were submitted to a peracetic acid 0.2% immersion for 10 minutes. Data of sorption and solubility were analyzed by two way ANOVA and, hardness values, by paired t-test. Results: Values of sorption and...

  18. Influence of peracetic acid at acrylic resin properties

    Hehn, Lisiane; Macedo, Érika de Oliveira Dias de; Collares, Fabrício Mezzomo; Leitune, Vicente Castelo Branco; Samuel, Susana Maria Werner
    Purpose: To evaluate the influence of peracetic acid immersion on water sorption, solubility and microhardness of heat and self-cured acrylic resins. Methods: Thirty specimens of each type of acrylic resin were produced for sorption, solubility and microhardness evaluation. Sorption and solubility were evaluated based on ISO1567. For the microhardness test, specimens (20.0×5.0×10.0 mm) were made and evaluated under a 100g load for 15 s. The test groups were submitted to a peracetic acid 0.2% immersion for 10 minutes. Data of sorption and solubility were analyzed by two way ANOVA and, hardness values, by paired t-test. Results: Values of sorption and...

  19. Body mass index, cognitive deficit and depressive symptoms in high cardiovascular risk patients

    Costa, Amanda Lucas da; Varela, Juliana Santos; Roriz-Cruz, Matheus; Costa, Andry Fiterman; Picon, Paulo Dornelles; Moriguchi, Emílio Hideyuki; Chaves, Marcia Lorena Fagundes
    To evaluate the relationship of obesity, cognitive impairment and depressive symptoms in patients with high cardiovascular risk. Methods: A sample of 93 patients aged 50 years or older was selected from the Center of Dyslipidemia and High Cardiovascular Risk from Hospital de Clínicas de Porto Alegre (HCPA). Patients with stroke were excluded. For cognitive evaluation, the MMSE (Mini Mental State Examination) was used. A score of 24 or less was considered as cognitive impairment, and for those who had 4 years or less of education, the cutoff point was 17. The GDS-15 (Geriatric Depression Scale) was also used, with the...

  20. Body mass index, cognitive deficit and depressive symptoms in high cardiovascular risk patients

    Costa, Amanda Lucas da; Varela, Juliana Santos; Roriz-Cruz, Matheus; Costa, Andry Fiterman; Picon, Paulo Dornelles; Moriguchi, Emílio Hideyuki; Chaves, Marcia Lorena Fagundes
    To evaluate the relationship of obesity, cognitive impairment and depressive symptoms in patients with high cardiovascular risk. Methods: A sample of 93 patients aged 50 years or older was selected from the Center of Dyslipidemia and High Cardiovascular Risk from Hospital de Clínicas de Porto Alegre (HCPA). Patients with stroke were excluded. For cognitive evaluation, the MMSE (Mini Mental State Examination) was used. A score of 24 or less was considered as cognitive impairment, and for those who had 4 years or less of education, the cutoff point was 17. The GDS-15 (Geriatric Depression Scale) was also used, with the...

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