PubMed Central (PMC3 - NLM DTD) (1.999.448 recursos) Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
2. Birth defects and anti–heat shock protein 70 antibodies in early pregnancy - Child, David F.; Hudson, Peter R.; Hunter-Lavin, Claire; Mukhergee, Sagarika; China, Susnata; Williams, Clive P.; Williams, John H. H. We measured serum heat shock protein 70 (Hsp70), anti-Hsp70, and anti-Hsp60 in samples taken from expectant mothers at 16 weeks gestation.
4. A genomewide analysis of genes for the heat shock protein 70 chaperone system in the ascidian Ciona intestinalis - Wada, Shuichi; Hamada, Mayuko; Satoh, Nori To shed light on the evolutionary history of the constituents of the chordate HSP70 chaperone system and to identify all of the components of the HSP70 chaperone system in ascidians, we carried out a comprehensive survey for HSP70s and their cochaperones in the genome of Ciona intestinalis.
7. Inhibition of apoptosis by p26: implications for small heat shock protein function during Artemia development - Villeneuve, Tania S.; Ma, Xiaocui; Sun, Yu; Oulton, Mindy M.; Oliver, Ann E.; MacRae, Thomas H. p26, an abundantly expressed small heat shock protein, is thought to establish stress resistance in oviparously developing embryos of the crustacean Artemia franciscana by preventing irreversible protein denaturation, but it might also promote survival by inhibiting apoptosis.
10. Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors - Torronteguy, Carolina; Frasson, Antonio; Zerwes, Felipe; Winnikov, Erik; da Silva, Vinicius Duval; Ménoret, Antoine; Bonorino, Cristina Murine tumors expressing high amounts of Hsp70 are preferentially rejected by the immune system, suggesting that low Hsp70 expression is advantageous for tumor growth in the host.
14. On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60 - Deocaris, Custer C.; Kaul, Sunil C.; Wadhwa, Renu The heat shock chaperones mortalin/mitochondrial heat shock protein 70 (mtHsp70) and Hsp60 are found in multiple subcellular sites and function in the folding and intracellular trafficking of many proteins.
15. Stress-induced phosphorylation of caveolin-1 and p38, and down-regulation of EGFr and ERK by the dietary lectin jacalin in two human carcinoma cell lines - Sahasrabuddhe, Anagh A.; Ahmed, Neesar; Krishnasastry, M.V. We have examined the A431 (human epidermoid carcinoma) and HT29 (human colorectal carcinoma) cellular responses evoked by lectins of dietary origin, Jacalin of Artocarpus integrifolia (native jacalin; nJacalin), peanut agglutinin (PNA) of Arachis hypogea, and recombinant single-chain jacalin (rJacalin), which has the same protein backbone but ?100-fold less affinity for carbohydrates than nJacalin.
17. Arctigenin from Fructus Arctii is a novel suppressor of heat shock response in mammalian cells - Ishihara, Keiichi; Yamagishi, Nobuyuki; Saito, Youhei; Takasaki, Midori; Konoshima, Takao; Hatayama, Takumi Because heat shock proteins (Hsps) are involved in protecting cells and in the pathophysiology of diseases such as inflammation, cancer, and neurodegenerative disorders, the use of regulators of the expression of Hsps in mammalian cells seems to be useful as a potential therapeutic modality.
18. Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner - Niu, Piye; Liu, Lin; Gong, Zhiyong; Tan, Hao; Wang, Feng; Yuan, Jing; Feng, Youmei; Wei, Qingyi; Tanguay, Robert M; Wu, Tangchun Heat shock protein 70 (Hsp70) comprises proteins that have been reported to protect cells, tissues, and organisms against damage from a wide variety of stressful stimuli; however, little is known about whether Hsp70 protects against DNA damage.
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