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The KnowledgeBank at OSU (30.651 recursos)
Knowledge Bank contains collections of presentations, publications and reports related to Ohio State University.

Mostrando recursos 1 - 12 de 12

1. EFFECT OF STRUCTURAL MODIFICATIONS OF ANTHRACYCLINE AGAINST DRUG-SENSITIVE AND RESISTANT CANCER CELLS - AIMIUWU, JOSEPHINE EKI
The clinical application of anthracycline antibiotics, daunorubicin (DNR) and doxorubicin is limited by the development of multidrug resistance (MDR) in cancer therapy.

2. Computational Studies on Effects of Cocaine on Fast-paced Dopamine Neurons - Choksy, Achint Viral
This project has investigated the effects of inhibition of the dopamine transporter on extracellular dopamine when dopaminergic neurons are electrically paced at rates substantially higher than those occurring in the brain.

3. Separation and Isolation of (S)-Equol: The Biologically Relevant Metabolite of the Isoflavone Daidzein - Kopec, Rachel
First Place, CFAES Forum, 2005.

4. Synthesis of Thieno[2,3]-pyrimidines as Candidate Antileishmanial Agents - Tkacz, Victoria
Undergraduate Student Government.

5. Enhancing the Care of Pregnant Women with Epilepsy: A Focus Group Approach - Patankar, Chetana
BACKGROUND: Through a long-standing collaboration with the Medical Center’s Maternal-Fetal Medicine program, a clinical pharmacist from the Comprehensive Epilepsy program works with pregnant women with epilepsy in the High-Risk Obstetrics Clinic.

6. In Vitro Stability and Pharmacokinetics of Novel Antileishmanial Compounds - Becker, Kimberly
In the first round of derivatization, several dinitroanilines were synthesized and evaluated in in vitro efficacy and stability and in vivo efficacy studies to identify key regions of the molecules for efficacy and metabolism.

7. The Role of NOD-Mediated Innate Immune Activation in Lung Epithelia - Bensman, Timothy J.
The ability to recognize and remove pathogens that invade the lower airway, while maintaining homeostasis in the lung microenvironment, is an essential function of the innate immune system.

8. An Evaluation of Medication Adherence and Self-Managment Techniques in Patients with Epilepsy - McFadden, Linsey
Denman Undergraduate Forum 2007 participant, OPA Research Forum presenter, OSU College of Pharmacy Research Day presenter.

9. ?-H2AX as a DNA damage marker to evaluate Suramin sensitization effect on Cisplatin in pancreatic cancer xenograft - Patel, Prachi
Purpose: ?-H2AX, a DNA double strand break marker, was used to evaluate suraminsensitization effect in cisplatin-treated Capan-1-bearing mice xenografts.

10. Computational Simulations of Dopaminergic Varicosities Suggest Two Sources of DOPAC Rather Than Two Populations of Dopamine Storage Vesicles - Hughes, Rachel
The goal of this project is to develop a computer simulation model of a dopaminergic varicosity that provides a plausible quantitative description of these populations and a possible set of rules for movement between two populations of vesicles.

11. An Assessment of Pharmacist & Patient Knowledge of and Attitudes Toward Reporting Adverse Drug Reactions in Patients with Epilepsy - Alyssa, Chen
Fourth Place at the 2008 Denman Undergraduate Research Forum.

12. Single Nucleotide Polymorphism in BCRP and Effects on Flavopiridol Transport - Tran, Linda
Flavopiridol is a promising therapeutic agent currently under phase I and phase II clinical investigation for the treatment of Chronic Lymphocytic Leukemia (CLL) and other hematologic and solid tumor malignancies.