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University of Twente Publications (60.076 recursos)

University of Twente Repository provides publications of UT scientific staff, in many cases full text and publicly available.

Type = Article

Mostrando recursos 1 - 20 de 27.316

  1. Treatment Dropout in Web-Based Cognitive Behavioral Therapy for Patients with Eating Disorders.

    Huurne, E.D. ter; Postel, M.G.; Haan, H.A. de; Palen, J.A.M. van der; Jong, C.A. de

  2. Pathologies of AI: Responsible use of artificial intelligence in professional work

    Stamper, Ronald
    Although the AI paradigm is useful for building knowledge-based systems for the applied natural sciences, there are dangers when it is extended into the domains of business, law and other social systems. It is misleading to treat knowledge as a commodity that can be separated from the context in which it is regularly used. Especially when it relates to social behaviour, knowledge should be treated as socially constructed, interpreted and maintained through its practical use in context. The meanings of terms in a knowledge-base are assumed to be references to an objective reality whereas they are instruments for expressing values...

  3. Study protocol for a non-inferiority trial of a blended smoking cessation treatment versus face-to-face treatment (LiveSmokefree-Study)

    Siemer, L.; Pieterse, M.E.; Brusse-Keizer, M.G.J.; Postel, M.G.; Ben Allouch, S.; Sanderman, R.

  4. Iedereen orgaandonor, tenzij ... [2]: Nee zo'n systeem bekrachtigt de medisch-technologische heerschappij

    Ossewaarde, Ringo; Ossewaarde-Lowtoo, Roshnee

  5. Socialism’s struggles with Eros: Politics of the body in Cuba and China

    Ossewaarde, Marinus
    In this review essay, the problematic relationship between socialism and eroticism is discussed, in defense of the erotic. The purpose of this essay is to keep sociological focus on the erotic sphere as a central source of creativity and transformation. The erotic – the transfiguration of sexual energy into cultural inventiveness by the imagination – is thought of as containing the potential to mitigate everyday disenchantment in rationalized worlds such as socialism. Megan Daigle’s From Cuba with Love and Everett Yuehong Zhang’s The Impotence Epidemic are reviewed as two important, fascinating, and well-investigated accounts of the erotic sphere in societies...

  6. Ja-kamp Oekraïne-referendum heeft beter verhaal nodig

    Kanne, Peter; Rosema, Martin

  7. Waarom was de opkomst bij het Oekraïnereferendum zo laag?

    Rosema, Martin

  8. Observation and experimental investigation of confinement effects on ion transport and electrokinetic flows at the microscale

    Benneker, Anne M.; Wood, Jeffery A.; Tsai, Peichun A.; Lammertink, Rob G.H.
    Electrokinetic effects adjacent to charge-selective interfaces (CSI) have been experimentally investigated in microfluidic platforms in order to gain understanding on underlying phenomena of ion transport at elevated applied voltages. We experimentally investigate the influence of geometry and multiple array densities of the CSI on concentration and flow profiles in a microfluidic set-up using nanochannels as the CSI. Particle tracking obtained under chronoamperometric measurements show the development of vortices in the microchannel adjacent to the nanochannels. We found that the direction of the electric field and the potential drop inside the microchannel has a large influence on the ion transport through...

  9. Predicting Sound Absorption of Stacked Spheres: Combining an Analytical and Numerical Approach

    Bezemer-Krijnen, M.; Wijnant, Y.H.; Boer, A. de
    Tire-road noise is a serious problem, but can be significantly reduced by the use of porous asphalt concrete. Here, the sound absorption of the porous asphalt concrete is important and can be predicted by ground impedance models. Yet, modeling porous asphalt concrete is complex, especially when nonlocal effects and scattering effects are considered. The objective of this research is to predict the sound absorption coefficient for a three-dimensional porous structure. The proposed solution is obtained using a novel modeling approach, in which the total solution of the sound field is found by combining the solutions of two subsystems: a background...

  10. Word associations with “Organic”: What do consumers think of

    Hilverda, F.; Jurgens, M.; Kuttschreuter, M.
    Purpose – The purpose of this paper is to examine the word associations that consumers have with organic food, organic meat or organic vegetables, and how these associations differ between food type and consumer groups. Construal-level theory was used as a theoretical framework to interpret the associations. In addition, consumer groups were compared on psychological distance, values, age, and gender. Design/methodology/approach – Two studies were performed. In Study 1, a sample of 154 participants filled out the words that came to their mind when thinking of organic food, organic meat or organic vegetables, and psychological distance and values were measured. In Study...

  11. Safety and Efficacy of New-Generation Drug-Eluting Stents in Women at High Risk for Atherothrombosis: From the Women in Innovation and Drug-Eluting Stents Collaborative Patient-Level Pooled Analysis

    Giustino, Gennaro; Baber, Usman; Salianski, Olga; Sartori, Samantha; Stone, Gregg W.; Leon, Martin B.; Aquino, Melissa; Stefanini, Giulio G.; Steg, Gabriel; Windecker, Stephan; O'Donoghue, Monica; Wijns, William; Serruys, Patrick W.; Valgimigli, Marco; Morice, Marie-Claude; Camenzind, Edoardo; Weisz, Giora; Smits, Pieter C.; Kandzari, David E.; Birgelen, Clemens von; Dangas, George D.; Cha, Jin Y.; Galatius, Soren; Jeger, Raban V.; Kimura, Takeshi; Mikhail, Ghada W.; Itchhaporia, Dipti; Mehta, Laxmi; Ortega, Rebecca; Kim, Hyo-Soo; Kastrati, Adnan; Genereux, Philippe; Chieffo, Alaide; Mehran, Roxana
    Background—The safety and efficacy of new-generation drug-eluting stents (DES) in women with multiple atherothrombotic risk (ATR) factors is unclear. Methods and Results—We pooled patient-level data for women enrolled in 26 randomized trials. Study population was categorized based on the presence or absence of high ATR, which was defined as having history of diabetes mellitus, prior percutaneous or surgical coronary revascularization, or prior myocardial infarction. The primary end point was major adverse cardiovascular events defined as a composite of all-cause mortality, myocardial infarction, or target lesion revascularization at 3 years of follow-up. Out of 10 449 women included in the pooled database, 5333...

  12. Technical Note: Cortical thickness and density estimation from clinical CT using a prior thickness-density relationship

    Humbert, Ludovic; Hazrati Marangalou, Javad; Río Barquero, Luis Miguel del; Lenthe, G. Harry van; Rietbergen, Bert van

  13. Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae

    Badilatti, Sandro D.; Christen, Patrik; Levchuk, Alina; Hazrati Marangalou, Javad; Rietbergen, Bert van; Parkinson, Ian; Müller, Ralph
    Identification of individuals at risk of bone fractures remains challenging despite recent advances in bone strength assessment. In particular, the future degradation of the microstructure and load adaptation has been disregarded. Bone remodeling simulations have so far been restricted to small-volume samples. Here, we present a large-scale framework for predicting microstructural adaptation in whole human vertebrae. The load-adaptive bone remodeling simulations include estimations of appropriate bone loading of three load cases as boundary conditions with microfinite element analysis. Homeostatic adaptation of whole human vertebrae over a simulated period of 10 years is achieved with changes in bone volume fraction (BV/TV)...

  14. Patient-specific biomechanical modeling of bone strength using statistically-derived fabric tensors

    Lekadir, Karim; Noble, Christopher; Hazrati Marangalou, Javad; Hoogendoorn, Corné; Rietbergen, Bert van; Taylor, Zeike A.; Frangi, Alejandro F.
    Low trauma fractures are amongst the most frequently encountered problems in the clinical assessment and treatment of bones, with dramatic health consequences for individuals and high financial costs for health systems. Consequently, significant research efforts have been dedicated to the development of accurate computational models of bone biomechanics and strength. However, the estimation of the fabric tensors, which describe the microarchitecture of the bone, has proven to be challenging using in vivo imaging. On the other hand, existing research has shown that isotropic models do not produce accurate predictions of stress states within the bone, as the material properties of...

  15. The effectiveness of percutaneous vertebroplasty is determined by the patient-specific bone condition and the treatment strategy

    Widmer Soyka, Rene P.; Helgason, Benedikt; Hazrati Marangalou, Javad; Bergh, Joop P. van den; Rietbergen, Bert van; Ferguson, Stephen J.
    Purpose Vertebral fragility fractures are often treated by injecting bone cement into the collapsed vertebral bodies (vertebroplasty). The mechanisms by which vertebroplasty induces pain relief are not completely understood yet and recent debates cast doubt over the outcome of the procedure. The controversy is intensified by inconsistent results of randomized clinical trials and biomechanical studies that have investigated the effectiveness or the change in biomechanical response due to the reinforcement. The purpose of this study was to evaluate the effectiveness of vertebroplasty, by varying the relevant treatment parameters and (a) computationally predicting the improvement of the fracture risk depending on the...

  16. Effect of Discontinuation of Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease: the COPE study

    Valk, Paul van der; Monninkhof, Evelyn; Palen, Job van der; Zielhuis, Gerhard; Herwaarden, Cees van
    The aim of this double-blind single center study (the COPE study) was to investigate the effect of discontinuation of the inhaled corticosteroid fluticasone propionate (FP) on exacerbations and health-related quality of life in patients with chronic obstructive pulmonary disease. After 4 months of treatment with FP (1,000 μg/day), 244 patients were randomized to either continue FP or to receive placebo for 6 months: 123 patients continued FP (FP group), and 121 received placebo (placebo group). In the FP group, 58 (47%) patients developed at least one exacerbation compared with 69 (57%) in the placebo group. The hazard ratio of a...

  17. Supporting the legal practitioner: LKBS or web?

    Leenes, Ronald; Svensson, Jörgen
    The legal practitioner is a knowledge worker. Two distinct technologies may be of assistance to this type of professional: legal knowledge‐based system technology and Internet World Wide Web technology. In this paper we investigate the relation between legal knowledge‐based systems and the Internet. Legal knowledge‐based systems have long been surrounded by much optimism, but despite the efforts over the last 20 years, the number of practical applications actually in use is still small. On the other hand, the WWW technology, which in a practical form has been around for only a few years, is gaining momentum and is expected to...

  18. The impact of age on local control in women with pT1 breast cancer treated with conservative surgery and radiation therapy

    Jobsen, J.J.; Palen, J. van der; Meerwaldt, J.H.
    The aim of the study was to evaluate the importance of young age with regard to local control in a prospective cohort of 1085 women with pathological T1 tumours treated with breast conservative treatment (BCT). Patients were divided into two age groups: 40 years or younger, 7.8%, and older than 40 years, 92.2%. With a median follow-up of 71 months, the local recurrence rate was 10.6% in women ⩽40 years, and 3.7% in older women. The local recurrence-free survival (LRFS) was significantly different for the two age groups, respectively 89%, ⩽40 years, and 97.6%, >40 years (P=0.0046). A separate analysis...

  19. Treatment results in women with clinical stage I and pathologic stage II endometrial carcinoma

    Jobsen, J.J.; Schutter, E.M.J.; Meerwaldt, J.H.; Palen, J. van der; Sijde, R. van der; Naudin Ten Cate, L.
    The aim of this study is to report survival and results of therapy and possible prognostic factors in women with pathologic stage II endometrial carcinoma. Forty-two patients with pathologic stage II endometrial carcinoma were treated at the department of Radiation Oncology of the Medisch Spectrum Twente between 1987 and 1998. All patients received external radiotherapy following standard surgical procedures and no adjuvant systemic therapy was given. From the 42 patients 21 had a pathologic stage IIA and 21 stage IIB. The median follow-up was 62 months. The overall recurrence rate was 21.5% (9/42). Seven patients had distant metastasis, of which...

  20. Factoren van belang voor vroege diagnose van tuberculeuze meningitis

    Nuver, J.; Vloedbeld, M.; Schoeman, J.F.; Gerritsen, J.; Palen, J. van der; Werf, T.S. van der; Hoekstra, M.O.
    Tuberculeuze meningitis kent een hoge incidentie in de West-Kaap van Zuid-Afrika. Toch wordt de diagnose vaak laat gesteld. In een retrospectieve studie onderzochten wij de factoren die van belang zijn voor de diagnostiek van tuberculeuze meningitis. Van alle 207 kinderen die tussen 1989 en 1996 voor behandeling van tuberculeuze meningitis waren opgenomen in Tygerberg Hospitaal (West-Kaap, Zuid-Afrika) werden door middel van statusonderzoek gegevens verkregen over de klinische presentatie en het liquoronderzoek. Vroege symptomen van tuberculeuze meningitis waren braken, koorts en klachten van de bovenste luchtwegen. Veruit de meeste kinderen (91,3%) hadden één of meer neurologische klachten. De gemiddelde duur van...

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