Performance of the Dutch SF-36 version 2 as a measure of health-related quality of life in patients with rheumatoid arthritis - Klooster ten, P.M.; Vonkeman, H.E.; Taal, E.; Siemons, L.; Hendriks, L.; Jong de, A.J.L.; Dutmer, E.A.J.; Riel van, P.L.C.M.; Laar van de, M.A.F.J.
BACKGROUND: The aim of this study was to examine the measurement properties of the Dutch SF-36 version 2 (SF-36v2) health survey in patients with rheumatoid arthritis (RA).
METHODS: Scaling assumptions, internal reliability, and internal construct validity were examined using available data from 1884 RA patients included in the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry. External construct validity and responsiveness to change were examined using baseline and 6-month follow-up data from a subset of 387 early RA patients participating in the DREAM remission induction cohort.
RESULTS: The individual items of the SF-36v2 adequately met scaling assumptions, although four items correlated too highly with...
Scale in regional environmental planning : the reconstruction of North-Brabant, The Netherlands - Kooiman, A.; Keshkamat, S.S.
Selection of scale in science and planning is often guided by ad-hoc decisions and arguments of accuracy and availability of existing data and resources. A more analytical approach to selection of scale and a bridge between theoretical insight and practical application is required. This paper reviews recent developments in thinking on theoretical concepts on scale from the perspective of geo-information science and compares these with a real life case. The concept of scale is framed as a three dimensional boundary object that explains scale choice as resultant of rationalities in reality-, model- and data scales. It is applied to a...
Plug and play: combining materials and technologies to improve bone regenerative strategies - Moroni, L.; Nandakumar, A.; Barrère, F.; Blitterswijk van, C.A.; Habibovic, P.
Despite recent advances in the development of biomaterials intended to replace natural bone grafts for the regeneration of large, clinically relevant defects, most synthetic solutions that are currently applied in the clinic are still inferior to natural bone grafts with regard to regenerative potential and are limited to non-weight-bearing applications. From a materials science perspective, we always face the conundrum of the preservation of bioactivity of calcium phosphate ceramics in spite of better mechanical and handling properties and processability of polymers. Composites have long been investigated as a method to marry these critical properties for the successful regeneration of bone...
A molecular dynamics study of non-Newtonian flows of simple fluids in confined and unconfined geometries - Hartkamp, Remco Marcel
Various fluid flow phenomena originate in the dynamics of the atoms that constitute the fluid. Studying fluids as a collection of atoms is key to a better understanding of, for example, non-Newtonian fluid flow behavior. Molecular dynamics (MD) is a very suitable tool for the study of fluids on the atomic level.
Many MD studies have been devoted to the behavior of homogeneous, unconfined fluids under either simple shear or extensional flows, while a combination of both flow types has not been studied extensively.
We use MD simulations and analysis tools for: (1) the study of various properties of a...
Collaborative Procurement: A Relational View of Buyer–Buyer Relationships - Walker, H.; Schotanus, F.; Bakker, E.; Harland, C.
Collaborative procurement is increasingly on the policy agenda in many countries, yet problems with collaboration occur. This article adopts a relational theory perspective to explore the enablers of and barriers to collaboration in purchasing, helping identify success factors. The authors adopted a mixed qualitative/quantitative methodology and interviewed 51 senior staffers in the United Kingdom. They found that collaborative public procurement is hindered by local politics and differing priorities, supplier resistance, reliance on suppliers for data, and a lack of common coding systems. Enabling factors for collaborating with local governments include dealing with local issues and buying from small and medium-sized...
Bioinformatics-based selection of a model cell type for in vitro biomaterial testing - Groen, N.; Peppel van de, J.; Yuan, H.; Leeuwen van, J.P.T.M.; Blitterswijk van, C.A.; Boer de, J.
Biomaterial properties can be tailored for specific applications via systematic and high-throughput screening of biomaterial–cell interactions. However, progress in material development is often hampered by the lack of adequate in vitro testing methods, frequently due to incomplete understanding of involved in vivo mechanisms. In line with drug discovery in pharmacology, a crucial step in assay development for biomaterial screening is the identification of a target to direct the screen against. Herein, the cell type to be used for screening is of essential importance and has to be carefully chosen. So far, few attention has been put on selecting a cell...
Retaliation against reporters of unequal treatment: Failing employee protection in The Netherlands - Svensson, J.S.; Genugten van, M.L.
Purpose – Equal treatment in the workplace is considered one of the most fundamental rights of employees. This right also implies that employees must be able to address any form of unequal treatment freely and effectively, without fear of retaliation. The purpose of this paper is to investigate the prevalence of retaliation against complaints of unequal treatment in The Netherlands and its underlying factors.
Design/methodology/approach – This article is based on a telephone survey among employees who filed a formal complaint about unequal treatment at work to the Dutch Equal Treatment Commission.
Findings – The main finding is that retaliation...
Employee perceptions of management relations as influences on job satisfaction and quit intentions - Frenkel, S.; Sanders, K.; Bednall, T.
In this paper we use a relational approach to investigate how employee perceptions of their relationships with three types of managers—senior, line, and human resource managers—are related to employees’ job satisfaction and intention to quit. Based on an employee survey (n = 1,533), and manager network data (n = 140) in ten organizations operating in Australia, we found that the extent of agreement between employees’ perceptions of their relations with senior and line management was positively related to these outcome variables. In addition, we found these relationships were strengthened in organizations where HR and line managers reported high-frequency communication between...
What makes teacher teams in a vocational education context effective? A qualitative study of managers' view on team working - Truijen, K.J.P.; Sleegers, P.J.C.; Meelissen, M.R.M.; Nieuwenhuis, A.F.M.
Purpose – At a time when secondary vocational education is implementing competence-based education (CBE) on a large scale, to adapt to the needs of students and of the labour market in a modern society, many vocational schools have recognised that interdisciplinary teacher teams are an important condition for this implementation. In order to provide students with the right competences for the labour market, different subject teachers should work and learn together and, by doing so, should be able to develop changes and improvements to ensure the effective implementation of CBE. In spite of the appeal of forming teacher teams in...