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UCL University College London Eprints (411.881 recursos)

UCL Eprints collects the work of UCL researchers and makes it freely available over the web, helping the worldwide scholarly community to discover UCL research. Institutional repositories like UCL Eprints complement the traditional academic publishing and scholarly communications processes. They raise the visibility of research and help to maximise its impact. UCL researchers are encouraged to deposit a copy of each journal article, conference paper, working paper, and any other research output, in the UCL Eprints at the earliest opportunity, ensuring that their research reaches as wide an audience as possible.

Mostrando recursos 1 - 20 de 64.304

  1. NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: A report from the AIEOP-AML group.

    Bisio, V; Zampini, M; Tregnago, C; Manara, E; Salsi, V; Di Meglio, A; Masetti, R; Togni, M; Di Giacomo, D; Minuzzo, S; Leszl, A; Zappavigna, V; Rondelli, R; Mecucci, C; Pession, A; Locatelli, F; Basso, G; Pigazzi, M

  2. Early indicators of self-esteem in teenagers: Findings from a nationally representative sample

    Cheng, H; Furnham, A
    © 2017 Elsevier LtdThis study explored a longitudinal data set of 3096 British sixteen year olds with data collected in 1970, 1980, and 1986. It examined how parental social status at birth; intelligence, locus of control and behavioural problems (all measured at age 10) influenced teenage self-esteem measured at age 16. There were two related measures of self-esteem: General and School setting. Correlational analysis showed locus of control beliefs, childhood intelligence scores, behavioural problems and parental social status were all significantly related to the self-esteem measures at age 16. Structural Equation Modelling showed that childhood locus of control, childhood intelligence...

  3. Students’ preferences for lecturers’ personalities

    Tan, S; Mansi, A; Furnham, A
    © 2017 UCUThe present study set out to examine students’ preferences for lecturers’ personality as a function of their classroom behaviour, core self-evaluations and self-rated character strengths. Various hypotheses were tested: first, students’ Big Five traits would significantly predict corresponding personality preferences for lecturers (the matching hypothesis); second, students’ core self-evaluation scores would significantly predict preferences for extraverted, agreeable and conscientious lecturers; and third, self-rated character strengths would also significantly predict extraverted, agreeable and conscientious lecturers. We also investigated difference in preferences among two ethnic groups (South East Asian/Chinese versus Caucasian/British). In all, 264 British students completed four questionnaires. Conscientiousness...

  4. Health Insurance and Children in Low- and Middle-income Countries: A Review

    Mitra, S; Palmer, M; Pullaro, S; Mont, D; Groce, N
    © 2017 Economic Society of Australia.We conduct the first systematic review of the impact of health insurance on children and their households in low- and middle-income countries where nine-tenths of the world's child population reside. We find only 13 studies for seven countries published between 2000 and 2014 which assess the insurance impacts for children, controlling for self-selection and heterogeneity. Nine out of 10 studies reviewed provide consistent evidence that health insurance provides financial protection. The results are more mixed for health utilisation and health outcomes. Policy-makers would benefit from additional research on whether and how health insurance benefits children.

  5. Extra costs of living with a disability: A systematized review and agenda for research.

    Mitra, S; Palmer, M; Kim, H; Mont, D; Groce, N
    BACKGROUND: There has been a growing interest in disability and poverty on the international research and policy stages. Poverty assessments for persons with disabilities may be affected by the experience of extra costs associated with a disability. OBJECTIVE: This article provides a systematized review of the global literature on the direct costs associated with living with a disability at the individual or household level. METHODS: We searched three databases for peer-reviewed journal articles that estimated extra costs associated with disability: Econlit, SocIndex and PubMed. RESULTS: We found 20 such studies conducted in 10 countries. These studies were predominantly from high-income...

  6. A blood gene expression biomarker of early Alzheimer's disease

    Hodges, A; Lunnon, K; Furney, S; Proitsi, P; Sattlecker, M; Dobson, R; Lourdusamy, A; Simmons, A; Coppola, G; Lupton, M; Soininen, H

  7. Predicting the progression of Alzheimer's disease by plasma-based biomarkers

    Riddoch-Contreras, J; Hye, A; Baird, A; Ashton, N; Sattlecker, M; Dobson, R; Ward, M; Pike, I; Lovestone, S

  8. Identifying novel CSF markers of brain atrophy in Alzheimer's disease and mild cognitive impairment using a multiplex panel of analytes

    Kiddle, S; Khan, W; Aguilar, C; Thambisetty, M; Sattlecker, M; Newhouse, S; Dobson, R; Simmons, A

  9. Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology

    Sattlecker, M; Pritchard, M; Proitsi, P; Kiddle, S; Newhouse, S; Simmons, A; Johnston, C; Leung, R; Dixit, A; Bazenet, C; Soininen, H; Kloszewska, I; Mecocci, P; Tsolaki, M; Vellas, B; Stewart, A; Williams, S; Nelson, S; Lovestone, S; Dobson, R

  10. Poster Abstracts

  11. Common Genetic Variation in the 3 '-BCL11B Gene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk The AortaGen Consortium

    Mitchell, GF; Verwoert, GC; Tarasov, KV; Isaacs, A; Smith, AV; Yasmin,; Rietzschel, ER; Tanaka, T; Liu, Y; Parsa, A; Najjar, SS; O'Shaughnessy, KM; Sigurdsson, S; De Buyzere, ML; Larson, MG; Sie, MPS; Andrews, JS; Post, WS; Mattace-Raso, FUS; McEniery, CM; Eiriksdottir, G; Segers, P; Vasan, RS; van Rijn, MJE; Howard, TD; McArdle, PF; Dehghan, A; Jewell, ES; Newhouse, SJ; Bekaert, S; Hamburg, NM; Newman, AB; Hofman, A; Scuteri, A; De Bacquer, D; Ikram, MA; Psaty, BM; Fuchsberger, C; Olden, M; Wain, LV; Elliott, P; Smith, NL; Felix, JF; Erdmann, J; Vita, JA; Sutton-Tyrrell, K; Sijbrands, EJG; Sanna, S; Launer, LJ; De Meyer, T; Johnson, AD; Schut, AFC; Herrington, DM; Rivadeneira, F; Uda, M; Wilkinson, IB; Aspelund, T; Gillebert, TC; Van Bortel, L; Benjamin, EJ; Oostra, BA; Ding, J; Gibson, Q; Uitterlinden, AG; Abecasis, GR; Cockcroft, JR; Gudnason, V; De Backer, GG; Ferrucci, L; Harris, TB; Shuldiner, AR; van Duijn, CM; Levy, D; Lakatta, EG; Witteman, JCM

  12. Baroreflex impairment and morbidity after major surgery

    Toner, A; Jenkins, N; Ackland, GL

  13. Energy landscape analysis of neuroimaging data.

    Ezaki, T; Watanabe, T; Ohzeki, M; Masuda, N
    Computational neuroscience models have been used for understanding neural dynamics in the brain and how they may be altered when physiological or other conditions change. We review and develop a data-driven approach to neuroimaging data called the energy landscape analysis. The methods are rooted in statistical physics theory, in particular the Ising model, also known as the (pairwise) maximum entropy model and Boltzmann machine. The methods have been applied to fitting electrophysiological data in neuroscience for a decade, but their use in neuroimaging data is still in its infancy. We first review the methods and discuss some algorithms and technical...

  14. Mind the gap: temporal discrimination and dystonia.

    Sadnicka, A; Daum, C; Cordivari, C; Bhatia, KP; Rothwell, JC; Manohar, S; Edwards, MJ
    BACKGROUND AND PURPOSE: One of the most widely studied perceptual measures of sensory dysfunction in dystonia is the temporal discrimination threshold (TDT) (the shortest interval at which subjects can perceive that there are two stimuli rather than one). However the elevated thresholds described may be due to a number of potential mechanisms as current paradigms test not only temporal discrimination but also extraneous sensory and decision-making parameters. In this study two paradigms designed to better quantify temporal processing are presented and a decision-making model is used to assess the influence of decision strategy. METHODS: 22 patients with cervical dystonia and...

  15. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia.

    Nasca, A; Scotton, C; Zaharieva, I; Neri, M; Selvatici, R; Magnusson, OT; Gal, A; Weaver, D; Rossi, R; Armaroli, A; Pane, M; Phadke, R; Sarkozy, A; Muntoni, F; Hughes, I; Cecconi, A; Hajnóczky, G; Donati, A; Mercuri, E; Zeviani, M; Ferlini, A; Ghezzi, D
    We report here the first families carrying recessive variants in the MSTO1 gene: compound heterozygous mutations were identified in two sisters and in an unrelated singleton case, who presented a multisystem complex phenotype mainly characterized by myopathy and cerebellar ataxia. Human MSTO1 is a poorly studied protein, suggested to have mitochondrial localization and to regulate morphology and distribution of mitochondria. As for other mutations affecting genes involved in mitochondrial dynamics, no biochemical defects typical of mitochondrial disorders were reported. Studies in patients' fibroblasts revealed that MSTO1 protein levels were strongly reduced, the mitochondrial network was fragmented and the fusion events...

  16. ExoMol Line List XXI: Nitric Oxide (NO)

    Wong, A; Yurchenko, SN; Bernath, P; Müller, HSP; McConkey, S; Tennyson, J
    Line lists for the ground electronic ground state for six major isotopologues of nitric oxide are presented. The line lists are constructed using empirical energy levels (and line positions) and high-level {\it ab inito} intensities. The energy levels were obtained using a combination of two approaches, from an effective Hamiltonian and from solving the rovibronic Schr\"{o}dinger equation variationally. The effective hamiltonian model was obtained through a fit to the experimental line positions of NO available in the literature for all six isotopologues using the programs SPFIT and SPCAT. The variational model was built through a least squares fit of the...

  17. Laboratory spectra of hot molecules: data needs for hot super-Earth exoplanets

    Tennyson, J; Yurchenko, SN
    The majority of stars are now thought to support exoplanets. Many of those exoplanets discovered thus far are categorized as rocky objects with an atmosphere. Most of these objects are however hot due to their short orbital period. Models suggest that water is the dominant species in their atmospheres. The hot temperatures are expected to turn these atmospheres into a (high pressure) steam bath containing remains of melted rock. The spectroscopy of these hot rocky objects will be very different from that of cooler objects or hot gas giants. Molecules suggested to be important for the spectroscopy of these objects...

  18. Specific biomarkers for C9orf72 FTD/ALS could expedite the journey towards effective therapies.

    Balendra, R; Moens, TG; Isaacs, AM


    Pellegata, AF; Tedeschi, A; Natarajan, D; Gjinovci, A; Then, J; Urbani, L; De Coppi, P

  20. SpeCond: a method to detect condition-specific gene expression.

    Cavalli, FM; Bourgon, R; Vaquerizas, JM; Luscombe, NM

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