UCL University College London Eprints
UCL Eprints collects the work of UCL researchers and makes it freely available over the web, helping the worldwide scholarly community to discover UCL research. Institutional repositories like UCL Eprints complement the traditional academic publishing and scholarly communications processes. They raise the visibility of research and help to maximise its impact. UCL researchers are encouraged to deposit a copy of each journal article, conference paper, working paper, and any other research output, in the UCL Eprints at the earliest opportunity, ensuring that their research reaches as wide an audience as possible.
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The Art and Politics of Ecology in India - Demos, TJ
This roundtable discussion with artist and activist Ravi Agarwal and film-maker and photographer Sanjay Kak, moderated by T J Demos, explores the politics of ecology in the Indian context. The conversation considers, among other works, Kak's film Words on Water (2002), which looks at the issue of big dams and their negative social-economic effects in the Narmada valley; and Agarwal's photographic installation Extinction, which examines the disappearance of vultures on the subcontinent owing to the development of animal pharmaceuticals used to maximize milk production. The conversation critically examines the introduction of neoliberalism in the Indian economy and political context, and...
Gangsters or Gandhians? The Political Sociology of the Maoist Insurgency in India - Kennedy, J
This article combines concepts from political sociology with evidence from newspaper reports, insurgent and state documents, and ethnographic studies in order to understand the nature of the Maoist insurgency in India. The first section argues that the insurgency should be conceptualized as a state building enterprise rather than organized crime. It demonstrates that both insurgent violence and fundraising serve, on the whole, the collective interests of the state building enterprise – i.e., to consolidate insurgent control in their base areas – rather than the private interests of individual insurgents. The second section seeks to understand how Maoist state builders undermine...
Seven on Seven : A Conversation with the Writers of Orca Book Publishers' Series - Ue, T
In his will, the adventurer David McLean arranges for each of his seven grandsons a different task that takes him to locations around the world. Seven the Series, published by Orca Book Publishers, brings together the boys' stories, and the work of Canadian young adult writers Eric Walters, John Wilson, Ted Staunton, Richard Scrimger, Norah McClintock, Sigmund Brouwer, and Shane Peacock. Founded in 1982, Orca Book's main warehouse and editorial offices are based in Victoria in British Columbia, Canada. The independent publisher has brought numerous Canadian writers to global attention. Since its publication, over 100,000 copies of Seven the Series...
‘For recuperation’: elegy, form, and the aleatory in B.S. Johnson's The Unfortunates - Jordan, J
B.S. Johnson's The Unfortunates (1969) is British fiction's predominant attempt to embrace aleatorism and to subvert linear causality: the chapters are unbound, and the text invites the reader to shuffle them before reading. Narrative can be understood as a means of containing the ever-present risk of death, of disease, of loss, and has as its impetus a curative trajectory: recuperation is, perhaps, implicit in narrative. The Unfortunates, however, defiantly refuses such comfort. Johnson, this essay asserts, uses his form to cancel the consolations of narrative construction, taking the infectious chains of narrative and repudiating any doctorial/authorial urge to trace the...
Abdominopelvic Splenosis—An Unusual Cause of Tenesmus - Cheung, KK; Wagner, T; Hall, M; Dvorkin, L
Splenosis is a rare condition defined as seeding and autotransplantation of splenic tissue, typically after blunt
abdominal trauma (e.g. from road traffic collision). Sites of splenosis ranging from intrathoracic to intrapelvic have
been reported, and symptoms vary greatly depending on the site and size of lesions. We present the use of Tc-99m
sulphur colloid SPECT/CT in diagnosing a case of multiple abdominopelvic splenosis as the cause of new-onset
tenesmus and constipation, which was initially thought to be due to colorectal malignancy, 47 years following the
initial abdominal trauma.
Study of Serum Leptin in Well-differentiated Thyroid Carcinoma: Correlation with Patient and Tumor Characteristics - Rehem, RA; Elwafa, WA; Elwafa, RA; Abdel-Aziz, TE
There is a proven relationship between obesity and several cancers including breast, endometrium, colorectal, and esophagus. With the increasing incidence of both obesity and thyroid cancer, we designed the present study to investigate a causal relationship between leptin, which is one of the well known adipokines, and well-differentiated thyroid cancer (WDTC).
Serum leptin levels were measured in 30 patients with WDTC and compared to 30 healthy control subjects before and 1 month after surgery. Other parameters studied included age, sex, body mass index, menopausal status in women, lymph node status, tumor size, and disease multifocality.
There were no differences between the two...
Autoimmune and autoinflammatory mechanisms in uveitis - Lee, RW; Nicholson, LB; Sen, HN; Chan, CC; Wei, L; Nussenblatt, RB; Dick, AD
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult; clinically, inflammation following such an insult is termed uveitis. The intra-ocular inflammation in uveitis may be clinically obvious as a result of infection (e.g. toxoplasma, herpes), but in the main infection, if any, remains covert. We now recognise that healthy tissues including the retina have regulatory mechanisms imparted by control of myeloid cells through receptors (e.g. CD200R) and soluble inhibitory factors (e.g. alpha-MSH), regulation of the blood...
Emissions Taxes and Abatement Regulation Under Uncertainty - Christiansen, V; Smith, S
We consider environmental regulation in a context where firms invest in abatement technology under conditions of uncertainty about subsequent abatement cost, but can subsequently adjust output in the light of true marginal abatement cost. Where an emissions tax is the only available instrument, policy faces a trade-off between the incentive to invest in abatement technology and efficiency in subsequent output decisions. More efficient outcomes can be achieved by supplementing the emissions tax with direct regulation of abatement technology, or by combining the tax with an abatement technology investment subsidy. We compare the properties of these alternative instrument combinations.
Only reasoned action? An interorganizational study of energy-saving behaviors in office buildings - Lo, SH; Peters, G-JY; van Breukelen, GJP; Kok, G
Substantial energy savings can be achieved by reducing energy use in office buildings. The reported study used a Theory of Planned Behavior (TPB) model extended with perceived habit to explain office energy-saving behaviors. One aim was to examine if organizational contextual variability independently predicted office energy-saving behaviors over and above TPB variables and self-reported habit. Another aim was to examine the relative predictive value of TPB variables and habit for energy-saving behaviors between organizational contexts. Survey data on energy-saving behaviors, TPB variables, and habit and number of office mates were collected from office workers of four organizations in the Netherlands....
The association of maternal prenatal psychosocial stress with vascular function in the child at age 10-11 years: findings from the Avon longitudinal study of parents and children - van Dijk, AE; Dawe, K; Deanfield, J; Stronks, K; Gemke, RJ; Vrijkotte, TG; Lawlor, DA
Objective To investigate whether (1) maternal psychosocial stress (depression/anxiety) during pregnancy is associated with offspring vascular function and (2) whether any association differs depending on the gestational timing of exposure to stress. We also investigated whether any association is likely to be due to intrauterine mechanisms by (3) comparing with the association of paternal stress with offspring vascular function and (4) examining whether any prenatal association is explained by maternal postnatal stress.
Methods and results Associations were examined in a UK birth cohort, with offspring outcomes (systolic and diastolic blood pressure, SBP and DBP, endothelial function assessed by brachial artery flow-mediated...
Botulinum toxin-A for the treatment of overactive bladder: UK contributions - Seth, JH; Panicker, JN; Fowler, CJ; Dowson, C; Khan, MS; Dasgupta, P; Sahai, A
Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways. For those with neurogenic detrusoroveractivity secondary to spinal cord injury or multiple sclerosis, the toxin is currently licensed in certain parts of theworld, including the UK. It is an effective treatment in those in whom antimuscarinics and conservative measures havefailed who have symptoms of OAB and or detrusor overactivity (DO). Methods: Treatment can be given in an outpatient setting and can be administered under local anaesthesia. Its efficacylasts for between six and 12 months. Results: It has an acceptable...
Serendipitous UV source catalogues for 10 years of XMM and 5 years of Swift - Yershov, VN
Two UV serendipitous source catalogues are presented which were compiled based on the observations with two similar UV telescopes, one being on-board the ESA’s XMM Newton observatory and another—on-board the NASA’s Swift satellite. Both telescopes have similar optical and registration systems providing photometry in three ultraviolet and three visible bands. After processing a 10 years long series of observations from XMM and 5 years from Swift, we have compiled two source catalogues containing more than 4 million sources for XMM and 6 million sources for Swift. We describe the processing algorithms and present catalogue characteristics in comparison with each other.
Cardiovascular Risk Factors from Early Life Predict Future Adult Cardiac Structural and Functional Abnormalities: A Systematic Review of the Published Literature - Ghosh, AK; Francis, DP; Chaturvedi, N; Kuh, D; Mayet, J; Hughes, AD; Hardy, RJ
Background: Clinical practice evaluates cardiovascular risk based on current risk factor (RF) levels [Blood pressure (BP), body mass index (BMI) and glycaemic control] largely disregarding previous risk-factor history over the totality of the life course. RFs are related to contemporaneous echocardiographic measures of cardiac structure and function which in turn are independently related to cardiovascular morbidity and mortality in cross-sectional studies. However, the effect of lifetime or earlier RF history on future echocardiographic changes has never been systematically examined.
Methods: A systematic review of the published literature identified 24 studies relating either earlier BP, BMI, glycaemic control or a combination to...
Functional Limbal Epithelial Cells Can Be Successfully Isolated From Organ Culture Rims Following Long-Term Storage - Tovell, VE; Massie, I; Kureshi, AK; Daniels, JT
PURPOSE. Because of a shortage of fresh corneal tissue for research, it was of interest to
investigate the potential of successfully isolating human limbal epithelial cells (hLECs) from
organ culture corneal-scleral (OCCS) rims.
METHODS. Superficial segments of corneal limbus were dissected and digested using
collagenase (0.5 mg/mL, 16 hours at 378C). Cell suspensions were separated into four
different growth conditions: corneal epithelial cell medium (CM); CM þ 3T3-Swiss albino
cells; stromal stem cell medium (SM); and SM þ 3T3 cells. Colony number, hLEC count, cell
density, and colony forming efficiency (CFE) were quantified to assess different growth
conditions. The expression profile associated with basal hLECs was assessed by