UCL University College London Eprints
UCL Eprints collects the work of UCL researchers and makes it freely available over the web, helping the worldwide scholarly community to discover UCL research. Institutional repositories like UCL Eprints complement the traditional academic publishing and scholarly communications processes. They raise the visibility of research and help to maximise its impact. UCL researchers are encouraged to deposit a copy of each journal article, conference paper, working paper, and any other research output, in the UCL Eprints at the earliest opportunity, ensuring that their research reaches as wide an audience as possible.
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Surf zone vortices near piecewise flat topography. - Hinds, A.K.
The motion of ideal shallow water vortices near piecewise flat topography is studied without background rotation for two choices of bottom topography. First, topography is chosen in the form of a rectilinear step change in depth. Finite area monopolar vortices which propagate steadily, without change in shape, parallel to the step are computed numerically. Next, the general motion of a pair of point vortices of arbitrary circulation near an escarpment is found explicitly using Hamiltonian techniques. Some vortex paths are periodic and for specific initial conditions each vortex comprising the pair translates parallel to the step. Comparisons to point vortex...
G alpha 12 and rhogef mediated regulation of neurotransmission in Caenorhabditis elegans. - Hiley, E.J.
The communication between neurons and other cells at chemical synapses, via the release of neurotransmitters, is a tightly regulated process. Regulation of the synaptic vesicle cycle, responsible for the release of neurotransmitters, controls the level of synaptic transmission. The identities of proteins involved in this regulation are gradually being elucidated using both in vitro and in vivo systems. In C. elegans adults the single Rho GTPase orthologue, RHO-1, stimulates neurotransmitter release at excitatory synapses at the neuromuscular junction. Expression of constitutively active RHO-1 increases release, whilst inhibition of endogenous RHO-1 by C3 transferase decreases release. RHO-1 stimulates release via two...
The origins and practice of science on British television - Boon, T; Gouyon, J-B
Television has become prominent as a medium at the same time as science and technology were becoming the major factors influencing public life in Britain. This chapter examines what science on television meant for several group of historical actors, viewers, scientists, broadcasters, and producers. It draws insights from the study of the history of the BBC Horizon series, and put it in contrast with the special case of natural history television. This chapter’s content is influenced by the rudimentary state of scholarship on the topic. And it calls for more research to be done on the history of British television...
‘Something simple and striking, if not amusing’ – the Freedom 7 special exhibition at the Science Museum, 1965 - Gouyon, J-B
From October 1965 to May 1966, the Science Museum in London displayed the American spacecraft Freedom 7, the first capsule in the NASA’s Mercury Programme to take a human on a sub-orbital flight. Archival records concerning this temporary display are extensive and contain written sources as well as photographic ones. This case therefore lends itself quite nicely to a study aimed at evaluating the comparative merits of these two types of records, for understanding the logic at play in the display, and for retrieving at least part of the visitors’ experience. Unwritten sources emerge from this comparison as invaluable records...
Uterine allotransplantation in a rabbit model using aorto-caval anastomosis: a long-term viability study. - Saso, S; Petts, G; Chatterjee, J; Thum, MY; David, AL; Corless, D; Boyd, M; Noakes, D; Lindsay, I; Del Priore, G; Ghaem-Maghami, S; Smith, JR
Uterine transplantation (UTx) has been proposed as a treatment option for women diagnosed with absolute uterine factor infertility. Allogeneic UTx has been attempted in a number of animal models, but achieving an adequate blood supply for the transplanted uterus still presents the biggest challenge. Microvascular re-anastomosis was unsuccessful in a number of animal models. The aim was to assess whether a large vessel aortic-caval vascular patch technique can bring about long-term graft survival after allogeneic UTx in a rabbit model.
Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial. - Lamb, SE; Williamson, EM; Heine, PJ; Adams, J; Dosanjh, S; Dritsaki, M; Glover, MJ; Lord, J; McConkey, C; Nichols, V; Rahman, A; Underwood, M; Williams, MA; on behalf of the Strengthening and Stretching for Rheumatoid Arthritis of the Hand Trial (SARAH) Trial Team,
Disease-modifying biological agents and other drug regimens have substantially improved control of disease activity and joint damage in people with rheumatoid arthritis of the hand. However, commensurate changes in function and quality of life are not always noted. Tailored hand exercises might provide additional improvements, but evidence is lacking. We estimated the effectiveness and cost-effectiveness of tailored hand exercises in addition to usual care during 12 months.
A mass assembly of associative mechanisms: A dynamical systems account of natural social interaction. - Duran, ND; Dale, R; Richardson, DC
The target article offers a negative, eliminativist thesis, dissolving the specialness of mirroring processes into a solution of associative mechanisms. We support the authors' project enthusiastically. What they are currently missing, we argue, is a positive, generative thesis about associative learning mechanisms and how they might give way to the complex, multimodal coordination that naturally arises in social interaction.
Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study. - Al-Chalabi, A; Calvo, A; Chio, A; Colville, S; Ellis, CM; Hardiman, O; Heverin, M; Howard, RS; Huisman, MH; Keren, N; Leigh, PN; Mazzini, L; Mora, G; Orrell, RW; Rooney, J; Scott, KM; Scotton, WJ; Seelen, M; Shaw, CE; Sidle, KS; Swingler, R; Tsuda, M; Veldink, JH; Visser, AE; van den Berg, LH; Pearce, N
Amyotrophic lateral sclerosis shares characteristics with some cancers, such as onset being more common in later life, progression usually being rapid, the disease affecting a particular cell type, and showing complex inheritance. We used a model originally applied to cancer epidemiology to investigate the hypothesis that amyotrophic lateral sclerosis is a multistep process.
Social psychology for dummies - Richardson, D
Written for psychology students, Social Psychology For Dummies is an accessible and entertaining introduction to the field.