Recursos de colección

UCL University College London Eprints (411.881 recursos)

UCL Eprints collects the work of UCL researchers and makes it freely available over the web, helping the worldwide scholarly community to discover UCL research. Institutional repositories like UCL Eprints complement the traditional academic publishing and scholarly communications processes. They raise the visibility of research and help to maximise its impact. UCL researchers are encouraged to deposit a copy of each journal article, conference paper, working paper, and any other research output, in the UCL Eprints at the earliest opportunity, ensuring that their research reaches as wide an audience as possible.

Mostrando recursos 301 - 320 de 64.279

  1. Clinical trials for elderly patients with multiple diseases (CHROMED) pilot study

    Middlemass, J; Siriwardena, AN; Pompilio, P; Isetta, V; Munaro, G; Castellani, AP; Macis, R; Zanaboni, P; Calverley, PM; Dellaca, R; Rosso, R; Windle, K; Vos, J; Dalmases, M; Janson, C; Malinovschi, A
    The problem COPD (Chronic Obstructive Pulmonary Disease) is a significant socioeconomic burden which, particularly when associated with comorbidities such as Chronic Heart Failure (CHF), markedly affects patient outcomes. Care models based on telemedicine systems that enable early diagnosis and treatment of exacerbations are advocated to reduce the impact of chronic diseases on patient outcomes and health service costs. CHROMED (www.chromed.eu) is an international EU-funded project aimed at developing a multi-centre clinical trial to evaluate the impact of a new integrated home care approach to reduce care costs and improve quality of life in COPD. The approach We collaborated in a...

  2. Peer assisted learning scheme for PhD students (PALs for PhD’s): A pilot study.

    Sisson, K; Vos, J
    PALs for PhDs offers support for PGRs relating to the social and emotional dimensions of studying for a PhD. This is something that is not always formally acknowledged. As a pedagogical approach it fits neatly between the apprenticeship model which dominates practice and the more formal cohort based programmes. Following further exploration PALs could offer an alternative approach to research education within the sector.

  3. Developing peer assisted learning

    Sisson, K; Vos, J
    This session showcases the approach of Peer Assisted Learning being piloted at the University of Lincoln. This new scheme for PhD students utilities the action learning set methodology.

  4. Cast adrift in the care system? A systematic scoping review of care navigation for older people with multimorbidity

    Vos, J; Windle, K; Siriwardena, N; Linehan, C
    With an increase in the older population, higher levels of multimorbidity and changes in the care landscape (e.g. specialisation, fragmentation), there is a need for greater insight into how suffering from two or more major chronic conditions affects patient experience of, and navigation through, the health and social care system. This study aims to gain an understanding of what information is available in the literature regarding care system navigation in the setting of older people with multimorbidity. A scoping review through five electronic databases was conducted together with a review of the grey literature on this topic. This resulted in...

  5. A systematic scoping review of care navigation for older people with multimorbidity

    Vos, J; Windle, K; Siriwardena, N; Linehan, C
    Introduction: The health and social care environment is being transformed by the needs of the aging population, higher levels of multimorbidity, and shifts in the care landscape, such as specialisation, ?privatisation? and fragmentation. Health and social care systems were not designed to appropriately support individuals with multimorbidities; primarily evolving to cater for single diseases and acute events. Nevertheless, there is now an urgent need to redesign existing structures and care delivery to address the needs of the population, ensuring individuals can access the right care at the right time and in the right place. If patients or users are unable...

  6. Feasibility of using the Health Information Technology Acceptance Model (HITAM) for assessing readiness to adopt telecare in older patients with multiple chronic diseases

    Vos, J; Middlemass, J; Windle, K; Siriwardena, N
    Introduction: Health information technology (HIT) has potential benefits for patient care, patient safety and reduced healthcare costs. For example, telecare (including remote monitoring and a clinical response to changes in measures) is associated with lower mortality, emergency admission rates and primary care contacts in patients with stable chronic obstructive pulmonary disease (COPD). There are seemingly many reasons behind slow uptake of HIT, including those which relate to service users, e.g., patients? concerns about loss of the ?human touch? in care. We aimed to explore factors that might explain use of telecare in older people with multimorbidities. Methods: We undertook a...

  7. Postgraduate conference 2015 [abstracts]

    Hughes, C
    .

  8. Systematic scoping review of care navigation for older people with multimorbidity

    Vos, J; Windle, K; Siriwardena, N; Linehan, C
    The problem: The health and social care environment is being transformed by the needs of the aging population, higher levels of multimorbidity, and shifts in the care landscape, e.g., specialisation and fragmentation. Health and social care systems were not designed to appropriately support individuals with multimorbidities; evolving to cater for single diseases and acute events. There is now an urgent need to redesign care structures and delivery to ensure individuals can access the right care at the right time and in the right place. If users are unable to adequately navigate health, social and third sector care, there is likely...

  9. Applicability of the Health Information Technology Acceptance Model in assessing readiness of older patients with multiple chronic diseases to adopt telecare qualitative study

    Vos, J; Middlemass, J; Windle, K; Siriwardena, N
    The problem Health information technology (HIT) has potential benefits for patient care, patient safety and reduced healthcare costs. For example, telecare (including remote monitoring and a clinical response to changes in measures) is associated with lower mortality, emergency admission rates and primary care contacts in patients with stable chronic obstructive pulmonary disease (COPD). There are many reasons for poor uptake of HIT, including those which relate to service users, e.g., patients’ concerns about loss of the ?human touch’ in care. We aimed to explore factors that might explain use of telecare in older people with multimorbidities. The approach We undertook...

  10. Re-thinking peer assisted learning for postgraduate research students

    Vos, J; Sisson, K
    The nature of research education is very specific and distinct to that of taught degrees and has been criticised for being individualistic and focused on supervision practice. As a result research students commonly report feelings of isolation, lack of peer support and disconnect from their school or department. Typical research degrees, especially PhD?s, have no taught content and the course of study as well as the progress rates differ for each student which makes the application of tradition peer assisted learning (PAL) modes problematic. They do however have process-related commonalities, types of problems that are peculiar to the PhD process...

  11. The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials.

    Clayton, GL; Smith, IL; Higgins, JPT; Mihaylova, B; Thorpe, B; Cicero, R; Lokuge, K; Forman, JR; Tierney, JF; White, IR; Sharples, LD; Jones, HE
    BACKGROUND: When designing and analysing clinical trials, using previous relevant information, perhaps in the form of evidence syntheses, can reduce research waste. We conducted the INVEST (INVestigating the use of Evidence Synthesis in the design and analysis of clinical Trials) survey to summarise the current use of evidence synthesis in trial design and analysis, to capture opinions of trialists and methodologists on such use, and to understand any barriers. METHODS: Our sampling frame was all delegates attending the International Clinical Trials Methodology Conference in November 2015. Respondents were asked to indicate (1) their views on the use of evidence synthesis...

  12. Effect of PI resistance mutations on viral load in patients on PI monotherapy

    Thompson, JA; Kityo, C; Walker, AS; Hakim, J; Kambugu, A; van Oosterhout, JJ; Siika, A; Mweemba, A; Van den Eede, P; Dunn, DT; Paton, NI

  13. Automating decentralized manufacturing of cell & gene therapy products

    Harrison, RP; Rafiq, QA; Medcalf, N

  14. Mixing theory for culture and harvest in bioreactors of human mesenchymal stem cells on microcarriers

    Nienow, AW; Rafiq, QA; Heathman, TRJ; Coopman, K; Hewitt, CJ

  15. Toward a scalable and consistent manufacturing process for the production of human MSCs


  16. Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms

    Nienow, AW; Hewitt, CJ; Heathman, TRJ; Glyn, VAM; Fonte, GN; Hanga, MP; Coopman, K; Rafiq, QA

  17. Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

    Heathman, TRJ; Rafiq, QA; Chan, AKC; Coopman, K; Nienow, AW; Kara, B; Hewitt, CJ

  18. Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate

    Heathman, TRJ; Stolzing, A; Fabian, C; Rafiq, QA; Coopman, K; Nienow, AW; Kara, B; Hewitt, CJ

  19. Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

    Rafiq, QA; Coopman, K; Nienow, AW; Hewitt, CJ

  20. Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production

    Heathman, TRJ; Stolzing, A; Fabian, C; Rafiq, QA; Coopman, K; Nienow, AW; Kara, B; Hewitt, CJ

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