ORBi Open Repository and Bibliography
In may 2007, the ULg's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (Board's decision).
This decision led to the official launch, in November 2008, of the ORBi platform including both the Academic Bibliography and the Institutional Repository of the Wallonia-Europe University Academy.
Engineering, computing & technology => Multidisciplinary, general & others
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Cellular regulation mechanisms : case study of up and down states in the Purkinje cell - Wehenkel, Marie
In 1963, Hodgkin and Huxley obtained the Nobel Prize to have shown that the electrical activity of a neuron could be modelled by an electrical RC circuit containing non-linear conductances. This discovery made it possible to reproduce the electrical behaviour of neurons with a level of detail that has steadily increased over the last fifty years as new quantitative knowledge became available about the specific ionic currents that regulate the activity of a given neuron. But models with too many details are often non-robust and too complex for analysis. As control engineers need simplified models for control design, experimental neurophysiologists...
Feedback loops: From cellular to network principles - Dethier, Julie
Biological rhythms play a major role in the functioning of the brain. However, the generation mechanisms and functions of these rhythms are still under debate and the question of which cellular details must be retained at the network level is largely open. In this presentation, I will highlight that cellular properties have a major impact at the network level, especially in the study of modulation and robustness. I will focus on a particular cellular property, a positive feedback loop in a specific timescale, and illustrate its network level impact with two simple examples: the modulation and robustness of an half-center...