ORBi Open Repository and Bibliography
In may 2007, the ULg's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (Board's decision).
This decision led to the official launch, in November 2008, of the ORBi platform including both the Academic Bibliography and the Institutional Repository of the Wallonia-Europe University Academy.
Life sciences => Veterinary medicine & animal health
An essential role for gamma-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle. - Palmeira, Leonor; Sorel, Océane; Van Campe, Willem; Boudry, Christel; Roels, Stefan; Myster, Françoise; Reschner, Anca; Coulie, Pierre G.; Kerkhofs, Pierre; Vanderplasschen, Alain; Dewals, Benjamin G
Wildebeests carry asymptomatically alcelaphine herpesvirus 1 (AlHV-1), a gamma-herpesvirus inducing malignant catarrhal fever (MCF) to several ruminant species (including cattle). This acute and lethal lymphoproliferative disease occurs after a prolonged asymptomatic incubation period after transmission. Our recent findings with the rabbit model indicated that AlHV-1 infection is not productive during MCF. Here, we investigated whether latency establishment could explain this apparent absence of productive infection and sought to determine its role in MCF pathogenesis. First, whole-genome cellular and viral gene expression analyses were performed in lymph nodes of MCF-developing calves. Whereas a severe disruption in cellular genes was observed, only...
Effects of environmental factors on yield and milking number in dairy cows milked by an automatic system located in pasture - Dufrasne, Isabelle; Robaye, Vincent; Knapp, Emilie; Istasse, Louis; Hornick, Jean-Luc
Nowadays, farmers have to manage larger herds but want, at the same time, benefit from a normal social life. The milking robot can bring solutions. Its use can reduce physical labour and allow flexibility. This technology results in a reduction in grazing even through grazing appears as a natural practice which is appreciated by the consumers. This project aims to develop strategies to use milking robots in pasture in order to benefit from advantages regarding feeding costs as well as animal welfare and health. It aims to study the effects of grass height, animal, days in milk, rotation cycle number...
Production laitière et nombre de traites de vaches laitières en prairie avec un robot: effets des facteurs environnementaux. - Dufrasne, Isabelle; Robaye, Vincent; Knapp, Emilie; Istasse, Louis; Hornick, Jean-Luc
En Belgique, comme dans d'autres pays européens, le recours à la traite robotisée est en augmentation. La majorité des troupeaux traits avec un robot ne pratique pas le pâturage car les exploitants considèrent que cette méthode n'est pas conciliable avec le pâturage. La fragmentation des parcelles est aussi un frein au pâturage. La mise en place d'un robot dans une structure mobile permet d'utiliser le même robot à l'étable en hiver et dans les prairies distantes de l'exploitation en été. L'objectif de cette étude est de tester l'effet de facteurs environnementaux, l'animal, la complémentation, la distance entre le robot et...
Concept of a mobile automatic milking system and first results at grazing - Dufrasne, Isabelle
In Europe, farmers have to manage larger herds but, at the same time, want to have a normal social life. So, the automatic milking system (AMS) can bring solutions. This technology implies in most cases, the cessation of grazing although grazing is appreciated by the consumers who consider it to be a natural practice. At the experimental farm of the University of Liege, the concept of a mobile milking robot has been developed with a private company. The prototype is used indoors during the winter season and is moved outdoors during the grazing season in pastures romote from the farm.
Seasonal change of Lymnaeid snails intermediate host of Fasciola gigantica in North and Central Vietnam - Bui Thi, Dung; Dang Tat, The; Pham Ngoc, Doanh; Losson, Bertrand; Saegerman, Claude; Caron, Yannick; Hoang Van, Hien; Ho Thi, Loan
Objective: The present study was undertaken to investigate the population dynamics of the intermediate hosts of Fasciola gigantica and the levels of infection in the snails. This would allow identifying the most important transmission periods and suggesting optimal snail control for the area.
Methods: Lymnaeid snails were monthly collected by hand picking in Ha Noi (Northern Vietnam) during the period from March 2010 to December 2011 and in Binh Dinh province (Central Vietnam) during the period May and September 2012. Collected snails from different sites were identified based on morphology and the partial 16S rDNA sequence and ITS-2 sequence. Snails were...
IN-VITRO EVALUATION OF A-5021 ANTI-VIRAL ACTIVITY AGAINST TESTUDINID HERPESVIRUS 3 AND INITIAL PHARMACOKINETIC STUDY IN HERMANN'S TORTOISE (Testudo hermanni) - Gandar, Frederic; Vrancken, Robert; Diez, Marianne; Remy, Christophe; Wera, Stéphane; Marlier, Didier; Vanderplasschen, Alain
Testudinid herpesvirus infections in tortoises belonging to the Testudinidae family are well known for decades, but their pathogenesis remains poorly understood and treatments are often empirical. This study describes the in vitro evaluation of selected anti-herpesvirus compounds against Testudinid Herpesvirus 3 (THV-3). A-5021, a compound with known broad-spectrum anti-herpetic activity, showed to be 9 times more potent than acyclovir, with an EC50 of 13.2 µM and inducing a complete inhibition of viral replication at 37.7 µM. Initial pharmacokinetic parameters were determined after a single sub-cutaneous administration of 5 and 10 mg/kg in Hermann’s tortoises (Testudo hermanni, n=3). Blood samples were...
Cis-acting inhibition of MHC class I-restricted epitope presentation by Alcelaphine herpesvirus 1 genome maintenance protein - Sorel, Océane; Myster, Françoise; Vanderplasschen, Alain; Dewals, Benjamin G
γ-Herpesviruses persist as latent episomes in actively dividing lymphocytes. Their consequent need to express a viral genome maintenance protein (GMP) during latency presents a potential immune target. However, the GMPs from several γ-herpesviruses have evolved related strategies to limit their own MHC class I epitope presentation to cytotoxic T lymphocytes (CTLs). Alcelaphine herpesvirus 1 (AlHV-1) is a γ-herpesvirus that persists asymptomatically in its natural host, the wildebeest. However, AlHV-1 transmission to a large number of susceptible ruminants, including cattle, results in the development of a lethal lymphoproliferative disease named malignant catarrhal fever (MCF). We recently observed that the AlHV-1 GMP-homologue...