Recursos de colección

ORBi Open Repository and Bibliography (268.864 recursos)

In may 2007, the ULg's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (Board's decision). This decision led to the official launch, in November 2008, of the ORBi platform including both the Academic Bibliography and the Institutional Repository of the Wallonia-Europe University Academy.

Human health sciences => Hematology

Mostrando recursos 1 - 20 de 1.012

  1. Different and synergistic effect of 5-Azacytidine and Rapamycin on ex vivo expansion of natural human T Regulatory cells

    Conteduca, Giuseppina
    Natural T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic potential. 5-Azacytidine (5-azaC) and Rapamycin (RAPA) are immunosuppressive drugs that promote selectively the expansion of CD4+CD25highFoxp3+ regulatory T cells.: We investigated whether 5-azaC and RAPA could be used together to promote the ex vivo expansion of Tregs purified from adult human peripheral blood.We found that 5-azaC helped maintain FOXP3 expression during the expansion process probably by promoting the conversion of T conventional (Tconv) in Treg, instead Rapa induces selectively apoptosis in Tconv cells and expansion in Treg. Addition...

  2. Different and synergistic effect of 5-Azacytidine and Rapamycin on ex vivo expansion of natural human T Regulatory cells

    Conteduca, Giuseppina
    Natural T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic potential. 5-Azacytidine (5-azaC) and Rapamycin (RAPA) are immunosuppressive drugs that promote selectively the expansion of CD4+CD25highFoxp3+ regulatory T cells. We investigated whether 5-azaC and RAPA could be used together to promote the ex vivo expansion of Tregs purified from adult human peripheral blood. : We found that 5-azaC helped maintain FOXP3 expression during the expansion process probably by promoting the conversion of T conventional (Tconv) in Treg, instead Rapa induces selectively apoptosis in Tconv cells and expansion in Treg....

  3. 5-Azacytidine and Rapamycin: different and synergistic effect on ex vivo expansion of natural human T Regulatory cells

    Conteduca, Giuseppina
    BACKGROUND: Natural T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic potential. 5-Azacytidine (5-azaC) and Rapamycin (RAPA) are immunosuppressive drugs that promote selectively the expansion of CD4+CD25highFoxp3+ regulatory T cells OBJECTIVE: We investigated whether 5-azaC and RAPA could be used together to promote the ex vivo expansion of Tregs purified from adult human peripheral blood. METHODS: CD4+CD25+ and CD4+CD25- T cells were isolated from PBMC of normal controls using Miltenyi beads and FACS ARIA sorting. These cells subsets were cultured in the presence of anti-CD3/CD28 antibodies and 200 IU/ml of...

  4. Recommandations pour la prevention et la prise en charge des hemorragies massives.

    TONGLET, Martin; LARBUISSON, Robert; GERARD, Christiane; Benoit, Yves; brusselmans, Koen; Deneys, Veronique; De Paep, Rudi; De Waele, Jan; Ickx, Brigitte; Lambermont, Micheline; Latinne, Dominique; Loix, Sebastien; Muylle, Ludo; Peerlinck, Katelijn; Selleslag, Dominik; Stockman, Willem; Szabo, Bertrand; Vanderlinden, Philippe; Zachee, Pierre; Hubner, Roland
    Avis 8831 du Conseil Superieur de la Sante (CSS)

  5. Relapse of AML after hematopoietic stem cell transplantation: methods of monitoring and preventive strategies. A review from the ALWP of the EBMT.

    Tsirigotis, P.; Byrne, M.; Schmid, C.; Baron, Frédéric; Ciceri, F.; Esteve, J.; Gorin, N. C.; Giebel, S.; Mohty, M.; Savani, B. N.; Nagler, A.
    Peer reviewed

  6. Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio.

    Versluis, J.; In 't Hout, F. E. M.; Devillier, R.; van Putten, W. L. J.; Manz, M. G.; Vekemans, M.-C.; Legdeur, M.-C.; Passweg, J. R.; Maertens, J.; Kuball, J.; Biemond, B. J.; Valk, P. J. M.; van der Reijden, B. A.; Meloni, G.; Schouten, H. C.; Vellenga, E.; Pabst, T.; Willemze, R.; Lowenberg, B.; Ossenkoppele, G.; Baron, Frédéric; Huls, G.; Cornelissen, J. J.
    Peer reviewed

  7. Low dose clofarabine in combination with a standard remission induction in patients 18-60 years with previously untreated intermediate and bad risk acute myeloid leukemia or high risk myelodysplastic syndrome: combined Phase I/II results of the EORTC/GIMEMA AML-14A Trial.

    Selleslag, Dominik; Suciu, Stefan; Meloni, Giovanna; Muus, Petra; Halkes, Constantijn J. M.; Venditti, Adriano; Ramadan, Safaa M.; Pruijt, Hans; Meert, Liv; Vignetti, Marco; Marie, Jean-Pierre; Wittnebel, Sebastian; de Witte, Theo; Amadori, Sergio; Willemze, Roelof; Baron, Frédéric
    Peer reviewed

  8. The place of viscoelastic testing in clinical practice.

    Hans, Grégory; Besser, Martin W.
    Peer reviewed

  9. Contraception hormonale chez l'adolescente avec thrombophilie biologique

    Minon, Jean-Marc; Vasbien, Myriam; DRESSE, Marie-Françoise; Pintiaux, Axelle
    Venous thromboembolism among pill users is rare but is a serious complication. Women with inherited thrombophilia are at increased risk when taking combined oral contraceptives. It is also truth for the contraceptive patch and vaginal ring. Hence, the adolescents with a know biological thrombophilia should not take htis type of hormonal conraception. However, some of these thrombophilia should not preclude use of estrogen containing contraception. Actually, if thrombophilia testing can be justified in asymptomtic patient at high risk, it is sometimes performed as screening in adolescent before estrogen-containnig contraception use ( non recommended). In these situations and considering the venous...

  10. Azacytidine mitigates experimental sclerodermic graft-versus-host disease

    Fransolet, Gilles; Ehx, Grégory; SOMJA, Joan; Delens, Loïc; Hannon, Muriel; Muller, Joséphine; DUBOIS, Sophie; Drion, Pierre; CAERS, Jo; Humblet-Baron, Stéphanie; DELVENNE, Philippe; Beguin, Yves; Conteduca, Giuseppina; Baron, Frédéric
    Peer reviewed

  11. Prophylactic donor lymphocyte infusion in patients with high-risk acute myeloid leukemia: ready for prime time?

    Baron, Frédéric; Beguin, Yves
    Peer reviewed

  12. Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation

    Mohty, M.; Malard, F.; Abecassis, M.; Aerts, E.; Alaskar, AS.; Aljurf, M.; Bader, P; Baron, Frédéric; Bazarbachi, A.; Blaise, D.; Ciceri, F.; Corbacioglu, S.; Dalle, JH.; Dignan, F.; Fukuda, T.; Huynh, A.; Masszi, T.; Michallet, M.; Nagler, A.; NiChoghaile, M.; Okamoto, S.; Pagliuca, A.; Peters, C.; Petersen, FB.; Richardson, PG.; Ruutu, T.; Savani, BN.; Wallhult, E.; Yakoub-Agha, I.; Duarte, RF.; Carreras, E.
    Peer reviewed

  13. Best allogeneic transplantation approach for AML patients in first CR: is delayed unrelated donor bone marrow transplantation better than immediate unrelated cord blood transplantation?

    Baron, Frédéric; Nagler, Arnon
    Peer reviewed

  14. Use of Tyrosine Kinase Inhibitors to Prevent Relapse After Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Position Statement of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

    Giebel, S.; Czyz, A.; Ottmann, O.; Baron, Frédéric; Brissot, E.; Ciceri, F.; Cornelissen, JJ.; Esteve, J.; Gorin, NC.; Savani, B.; Schimd, C.; Mohty, M.; Nagler, A.
    Peer reviewed

  15. Galectin-1 is involved in osteoclast biology

    Muller, Joséphine; Binsfeld, Marilène; DUBOIS, Sophie; Carmeliet, Geert; BEGUIN, Yves; Heusschen, Roy; CAERS, Jo

  16. Paravertebral Burkitt’s Lymphoma in a Child: An Unusual Presentation

    Hoyoux, Claire; FORGET, Patricia; Piette, Caroline; DRESSE, Marie-Françoise; Florkin, B; Rausin, L; THIRY, Albert
    Peer reviewed

  17. An estimation of the incidence and demographic picture of the major hemoglobinopathies in Belgium (from a confidential inquiry)

    GULBIS, B; FERSTER, A; VERMYLEN, C; DRESSE, Marie-Françoise; VANDERFAEILLIE, A; DELANNOY, A; LABARQUE, V; PHILIPPET, P; KENTOS, A; SZTERN, B; DE PRIJCK, Bernard; VERTONGEN, F
    Peer reviewed

  18. Schizencephaly associated with a severe prothrombotic syndrome caused by antithombin III deficiency

    Daron, Aurore; DRESSE, Marie-Françoise; Hoyoux, Claire; Tebache, Malek; MISSON, Jean-Paul; DEBRAY, François-Guillaume
    Peer reviewed

  19. Circadian and seasonal variations of hematopoiesis in cord blood.

    Baudoux, E.; Beguin, Yves; Cornu, G.; Brichard, B.; Debruyn, C.; De Bruyere, M.; De Hemptinne, D.; Delforge, A.; Deneys, V.; Fillet, Georges; Germeau, N.; Joris, I.; Lefevre, P.; Massy, M.; Paulus, Jean-Michel; Raymakers, N.; Schaaps, Jean-Pierre; Sondag-Thull, Danièle; Van Cauwenberge, Jean-Rémy; Vermylen, C.; Strijckmans, P.
    Peer reviewed

  20. Isolement du mégacaryocyte

    Paulus, Jean-Michel

Aviso de cookies: Usamos cookies propias y de terceros para mejorar nuestros servicios, para análisis estadístico y para mostrarle publicidad. Si continua navegando consideramos que acepta su uso en los términos establecidos en la Política de cookies.