ORBi Open Repository and Bibliography
In may 2007, the ULg's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (Board's decision).
This decision led to the official launch, in November 2008, of the ORBi platform including both the Academic Bibliography and the Institutional Repository of the Wallonia-Europe University Academy.
Study of the specific interaction between fluorescent PDMAEMA and Platelets compared to Erythrocytes - Flebus, Luca; Lombart, François; Martinez, Lucia; Defraigne, Jean-Olivier; Delierneux, Céline; Oury, Cécile; Grandfils, Christian
Nowadays synthetic polymers provide more and more functionalities in the biomedical world,
in particular as part of medical devices and drug delivery systems. Looking for new applications in the
cardiovascular field, our attention has been focused on the well-known poly(2-(dimethylamino)ethyl
methacrylate polymer (PDMAEMA). This synthetic polycation has particularly been studied as a
potential DNA carrier to promote cell transfection. However and surprisingly enough relative few
studies have been published in order to better understand its hemoreactivity under a free form (thus not
based on “PolyElectrolyte Complex”), but also its biodistribution and clearance kinetics. In order to
facilitate the in vitro and in vivo monitoring of this polycation...
Cord blood banking Introduction-State of the art - BAUDOUX, Etienne
Since the early years 1990 when the first cord blood (CB) banks were created, the worldwide inventory has grown considerably to a current 590 thousand units that complement the 22 M donors to provide hematopoietic progenitor cells (HPC) to patients in need of an allogeneic transplantation. The existing inventory shows a high degree of heterogeneity with a significant number of units below the current transplantation standards for adult patients. In the mean time, the use of CB as a HPC source has remained steady over the last years, leading to a relative decrease in the release activity in each individual...
Autologous Blood Donation Plus Epoetin Alfa in Nonanemic Orthopedic Surgery Patients - Baudoux, Etienne
Intravenous (i.v.) administration of epoetin alfa facilitates the collection of autologous blood (AB) prior to elective orthopedic surgery. However, the optimum dose and dosage regimen remains to be defined. The aim of this multicenter, randomized, placebo-controlled study was to determine the optimum i.v. dose of epoetin alfa (300 IU/kg or 600 IU/kg) that would allow nonanemic patients to donate > or = 4 units of AB within 14 to 21 days of elective orthopedic surgery. All patients (n = 103) received oral iron supplementation and were treated with epoetin alfa or placebo three times during 1 week, within 3 weeks...