ORBi Open Repository and Bibliography
In may 2007, the ULg's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (Board's decision).
This decision led to the official launch, in November 2008, of the ORBi platform including both the Academic Bibliography and the Institutional Repository of the Wallonia-Europe University Academy.
Human health sciences => Radiology, nuclear medicine & imaging
Evaluation of aptamers for targeted radiotherapy: Binding specificity and labelling with natural lutetium - Gijs, Marlies
Many cancer patients suffer from serious side effects when treated with external beam radiotherapy or chemotherapy because of damage to healthy tissues by lack of selectivity. In this regard, specific targeting of tumours through radiopharmaceuticals is increasingly considered as a promising strategy in oncology. Radiopharmaceuticals consist of a radionuclide coupled to a vector that specifically targets cancer-related molecules.
Aptamers are small (5-15 kDa) synthetic oligonucleotides (DNA or RNA) that possess several advantages compared to other vectors, such as an relatively easy and cheap chemical synthesis allowing the introduction of different chemical modifications, a selection possible against almost every target, a...