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PubMed Central (PMC3 - NLM DTD) (1.998.476 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).

Mostrando recursos 1 - 20 de 1.708

1. Key stages in mammary gland development - Involution: apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ - Watson, Christine J
Involution of the mammary gland is an essential process that removes the milk-producing epithelial cells when they become redundant at weaning.

2. The intraductal approach to the breast: raison d'être - King, Bonnie L; Love, Susan M
Opportunities for the detection, prediction, and treatment of breast cancer exist at three biological levels: systemically via the blood, at the whole organ level, and within the individual ductal lobular structures of the breast.

3. Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium - Oakes, Samantha R; Hilton, Heidi N; Ormandy, Christopher J
Endocrine signals generated predominantly by prolactin and progesterone operate the alveolar switch to initiate these developmental events.

4. Overdiagnosis and overtreatment of breast cancer: Is overdiagnosis an issue for radiologists? - Warren, Ruth; Eleti, Asha
Overdiagnosis is diagnosis of cancers that would not present within the life of the patient and is one of the downsides of screening.

5. Overdiagnosis and overtreatment of breast cancer: Progression of ductal carcinoma in situ: the pathological perspective - Jones, J Louise
Ductal carcinoma in situ (DCIS) is encountered much more frequently in the screening population compared to the symptomatic setting.

6. Is there a positive association between mammographic density and bone mineral density? Authors' response - Crandall, Carolyn; Palla, Shana; Reboussin, Beth A; Ursin, Giske; Greendale, Gail

7. What can be learnt from models of incidence rates? - Colditz, Graham A; Rosner, Bernard A
Models of breast cancer incidence have evolved from the observation by Armitage and Doll in the 1950s that the pattern of incidence by age differs for reproductive cancers from those of other major malignancies.

8. Breast cancer, stem cells and prospects for therapy - Lynch, Magnus D; Cariati, Massimiliano; Purushotham, Anand D
The mammary epithelium contains multipotent stem cells that give rise to all differentiated cell types present within the tissue.

9. Array-CGH and breast cancer - van Beers, Erik H; Nederlof, Petra M
The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast cancer, because it obviated the need to culture cells before their chromosomes could be analyzed.

10. High-throughput genomic technology in research and clinical management of breast cancer. Evolving landscape of genetic epidemiological studies - Low, Yen-Ling; Wedrén, Sara; Liu, Jianjun
Candidate polymorphism-based genetic epidemiological studies have yielded little success in the search for low-penetrance breast cancer susceptibility genes.

11. Bone versus breast density - Cuzick, Jack
The common link with oestrogen levels suggests that bone mineral density and mammographic density might also be linked.

12. Key stages in mammary gland development - Involution: apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ - Watson, Christine J
Involution of the mammary gland is an essential process that removes the milk-producing epithelial cells when they become redundant at weaning.

13. The intraductal approach to the breast: raison d'être - King, Bonnie L; Love, Susan M
Opportunities for the detection, prediction, and treatment of breast cancer exist at three biological levels: systemically via the blood, at the whole organ level, and within the individual ductal lobular structures of the breast.

14. Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium - Oakes, Samantha R; Hilton, Heidi N; Ormandy, Christopher J
Endocrine signals generated predominantly by prolactin and progesterone operate the alveolar switch to initiate these developmental events.

15. Overdiagnosis and overtreatment of breast cancer: Is overdiagnosis an issue for radiologists? - Warren, Ruth; Eleti, Asha
Overdiagnosis is diagnosis of cancers that would not present within the life of the patient and is one of the downsides of screening.

16. Overdiagnosis and overtreatment of breast cancer: Progression of ductal carcinoma in situ: the pathological perspective - Jones, J Louise
Ductal carcinoma in situ (DCIS) is encountered much more frequently in the screening population compared to the symptomatic setting.

17. Is there a positive association between mammographic density and bone mineral density? Authors' response - Crandall, Carolyn; Palla, Shana; Reboussin, Beth A; Ursin, Giske; Greendale, Gail

18. What can be learnt from models of incidence rates? - Colditz, Graham A; Rosner, Bernard A
Models of breast cancer incidence have evolved from the observation by Armitage and Doll in the 1950s that the pattern of incidence by age differs for reproductive cancers from those of other major malignancies.

19. Breast cancer, stem cells and prospects for therapy - Lynch, Magnus D; Cariati, Massimiliano; Purushotham, Anand D
The mammary epithelium contains multipotent stem cells that give rise to all differentiated cell types present within the tissue.

20. Array-CGH and breast cancer - van Beers, Erik H; Nederlof, Petra M
The introduction of comparative genomic hybridization (CGH) in 1992 opened new avenues in genomic investigation; in particular, it advanced analysis of solid tumours, including breast cancer, because it obviated the need to culture cells before their chromosomes could be analyzed.

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