PubMed Central (PMC3 - NLM DTD) (1.999.448 recursos) Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
2. Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection - Betts, Michael R.; Exley, Barbara; Price, David A.; Bansal, Anju; Camacho, Zenaido Tres; Teaberry, Vanessa; West, Sadie M.; Ambrozak, David R.; Tomaras, Georgia; Roederer, Mario; Kilby, J. Michael; Tartaglia, Jim; Belshe, Robert; Gao, Feng; Douek, Daniel C.; Weinhold, Kent J.; Koup, Richard A.; Goepfert, Paul; Ferrari, Guido Worldwide HIV-1 vaccine efforts are guided by the principle that HIV-specific T cell responses may provide protection from infection or delay overt disease.
3. The protooncogene MYC can break B cell tolerance - Refaeli, Yosef; Field, Kenneth A.; Turner, Brian C.; Trumpp, Andreas; Bishop, J. Michael The protooncogene MYC has been implicated in both the proliferation and programmed cell death of lymphoid cells, and in the genesis of lymphoid tumors.
4. Risk preference instability across institutions: A dilemma - Berg, Joyce; Dickhaut, John; McCabe, Kevin In this article we use laboratory experiments to ask a fundamental question: Do individuals behave as if their risk preferences are stable across institutions.
5. Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis - Webster, Kylie E.; O'Bryan, Moira K.; Fletcher, Stephen; Crewther, Pauline E.; Aapola, Ulla; Craig, Jeff; Harrison, Dion K.; Aung, Hnin; Phutikanit, Nawapen; Lyle, Robert; Meachem, Sarah J.; Antonarakis, Stylianos E.; de Kretser, David M.; Hedger, Mark P.; Peterson, Pärt; Carroll, Bernard J.; Scott, Hamish S. Dnmt3L, a DNA methyltransferase regulator, is expressed during gametogenesis, and its deletion results in sterility.
7. On the utility of pooling biological samples in microarray experiments - Kendziorski, C.; Irizarry, R. A.; Chen, K.-S.; Haag, J. D.; Gould, M. N. Pooling affects data quality and inference, but the exact effects are not yet known because pooling has not been systematically studied in the context of microarray experiments.
8. Segmental trisomy of chromosome 17: A mouse model of human aneuploidy syndromes - Vacík, Tomáš; Ort, Michael; Gregorová, So?a; Strnad, Petr; Blatný, Radek; Conte, Nathalie; Bradley, Allan; Bureš, Jan; Forejt, Ji?í Several mouse models of Down's syndrome, triplicating 33–104 genes of Chr16, were designed in an attempt to analyze the contribution of specific orthologous genes to particular developmental features.
9. Reversible self-assembly and directed assembly of DNA-linked micrometer-sized colloids - Valignat, Marie-Pierre; Theodoly, Olivier; Crocker, John C.; Russel, William B.; Chaikin, Paul M. We present a technique for the directed assembly and self-assembly of micrometer-scale structures based on the control of specific DNA linkages between colloidal particles.
11. Remote analysis of biological invasion and biogeochemical change - Asner, Gregory P.; Vitousek, Peter M. We used airborne imaging spectroscopy and photon transport modeling to determine how biological invasion altered the chemistry of forest canopies across a Hawaiian montane rain forest landscape.
14. Low O2 tensions and the prevention of differentiation of hES cells - Ezashi, Toshihiko; Das, Padmalaya; Roberts, R. Michael hES cells, however, are generally cultured under an atmosphere of 21% O2 (normoxia), under which conditions they tend to differentiate spontaneously.
15. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function - Neve, Bernadette; Fernandez-Zapico, Martin E.; Ashkenazi-Katalan, Vered; Dina, Christian; Hamid, Yasmin H.; Joly, Erik; Vaillant, Emmanuel; Benmezroua, Yamina; Durand, Emmanuelle; Bakaher, Nicolas; Delannoy, Valerie; Vaxillaire, Martine; Cook, Tiffany; Dallinga-Thie, Geesje M.; Jansen, Hans; Charles, Marie-Aline; Clément, Karine; Galan, Pilar; Hercberg, Serge; Helbecque, Nicole; Charpentier, Guillaume; Prentki, Marc; Hansen, Torben; Pedersen, Oluf; Urrutia, Raul; Melloul, Danielle; Froguel, Philippe KLF11 (TIEG2) is a pancreas-enriched transcription factor that has elicited significant attention because of its role as negative regulator of exocrine cell growth in vitro and in vivo.
17. Application of genome-wide expression analysis to human health and disease - Cobb, J. Perren; Mindrinos, Michael N.; Miller-Graziano, Carol; Calvano, Steve E.; Baker, Henry V.; Xiao, Wenzhong; Laudanski, Krzysztof; Brownstein, Bernard H.; Elson, Constance M.; Hayden, Douglas L.; Herndon, David N.; Lowry, Stephen F.; Maier, Ronald V.; Schoenfeld, David A.; Moldawer, Lyle L.; Davis, Ronald W.; Tompkins, Ronald G.; The application of genome-wide expression analysis to a large-scale, multicentered program in critically ill patients poses a number of theoretical and technical challenges.
18. Methods to improve the detection of mild cognitive impairment - Shankle, William R.; Romney, A. Kimball; Hara, Junko; Fortier, Dennis; Dick, Malcolm B.; Chen, James M.; Chan, Timothy; Sun, Xijiang We examined whether the performance of the National Institute of Aging's Consortium to Establish a Registry for Alzheimer's Disease's 10-word list (CWL), part of the consortium's neuropsychological battery, can be improved for detecting Alzheimer's disease and related disorders early.
20. Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease - Madhavarao, Chikkathur N.; Arun, Peethambaran; Moffett, John R.; Szucs, Sylvia; Surendran, Sankar; Matalon, Reuben; Garbern, James; Hristova, Diana; Johnson, Anne; Jiang, Wei; Namboodiri, M. A. Aryan Canavan's disease (CD) is a fatal, hereditary disorder of CNS development that has been linked to mutations in the gene for the enzyme aspartoacylase (ASPA) (EC 3.5.1.15).
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