PubMed Central (PMC3 - NLM DTD)
(2,081,148 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
Mostrando recursos 121 - 140 de 3,096
121.
Inconvenient truths - Petsko, Gregory A
Science is not immune to meaningless locutions and genomics is rapidly acquiring its own set. They are used as a way of camouflaging the truth.
122.
Mouse maps of gene expression in the brain - Koester, Susan E; Insel, Thomas R
Comprehensive atlases of gene expression in the mouse brain will provide a great resource for neurobiology.
124.
A rational route to probing membrane proteins - Keating, Amy E
Computationally designed peptides against transmembrane helices point to new approaches to studying membrane protein function.
125.
The fungal frontier - Blankenship, Jill R; Mitchell, Aaron P
A report of the 24th Fungal Genetics Conference, Asilomar, USA, 20-25 March 2007.
126.
Chickens get their place in the sun - Rallis, Charalampos
A report on the International Chick Meeting 'The Chick as a Model Organism: Genes, Development and Function', Barcelona, Spain, 11-14 April 2007.
127.
The integrins - Takada, Yoshikazu; Ye, Xiaojing; Simon, Scott
An overview of a family of cell-surface adhesion and signaling receptors that mediate cell-cell adhesion and cell-extracellular matrix adhesion.
128.
Building on basic metagenomics with complementary technologies - Warnecke, Falk; Hugenholtz, Philip
Supplementing metagenomic approaches to studying natural microbial communities with metatranscriptomics and metaproteomics should reap big dividends
129.
Genomic clues to an ancient asexual scandal - Rice, William R; Friberg, Urban
The bdelloid rotifers are a successful and diverse group of organisms, despite being entirely asexual. How do they do it?
130.
Gene prediction: compare and CONTRAST - Flicek, Paul
The new gene-prediction program CONTRAST offers significant advances in accuracy over previous methods.
131.
The reticulons: a family of proteins with diverse functions - Yang, Yvonne S; Strittmatter, Stephen M
The reticulon family is a diverse group of proteins that mostly localize to the endoplasmic reticulum and may be important in neurodegenerative diseases.
132.
The ins and outs of translation - Clancy, Jennifer L; Nousch, Marco; Rodnina, Marina; Preiss, Thomas
A report on the 2nd EMBO Conference on Protein Synthesis and Translational Control, Heidelberg, Germany, 12-16 September 2007.
135.
Diversity and evolution of phycobilisomes in marine Synechococcus spp.: a comparative genomics study - Six, Christophe; Thomas, Jean-Claude; Garczarek, Laurence; Ostrowski, Martin; Dufresne, Alexis; Blot, Nicolas; Scanlan, David J; Partensky, Frédéric
By comparing Synechococcus genomes, candidate genes required for the production of phycobiliproteins, which are part of the light-harvesting antenna complexes called phycobilisomes, were identified. Phylogenetic analyses suggest that the phycobilisome core evolved together with the core genome, whereas rods evolved independently.
137.
Gene-expression patterns reveal underlying biological processes in Kawasaki disease - Popper, Stephen J; Shimizu, Chisato; Shike, Hiroko; Kanegaye, John T; Newburger, Jane W; Sundel, Robert P; Brown, Patrick O; Burns, Jane C; Relman, David A
Analysis of patterns of gene expression in peripheral blood from children with Kawasaki disease revealed dynamic and variable gene expression programs involving neutrophil activation and apoptosis.
138.
Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes - Curtis, Christina; Landis, Gary N; Folk, Donna; Wehr, Nancy B; Hoe, Nicholas; Waskar, Morris; Abdueva, Diana; Skvortsov, Dmitriy; Ford, Daniel; Luu, Allan; Badrinath, Ananth; Levine, Rodney L; Bradley, Timothy J; Tavaré, Simon; Tower, John
Transcriptional profiling of MnSOD-mediated life-span extension in Drosophila identifies a set of candidate biomarkers of aging, consisting primarily of carbohydrate metabolism and electron transport genes.
139.
Determining promoter location based on DNA structure first-principles calculations - Goñi, J Ramon; Pérez, Alberto; Torrents, David; Orozco, Modesto
A new method is presented which predicts promoter regions based on atomistic molecular dynamics simulations of small oligonucleotides, without requiring information on sequence conservation or features.
140.
Evolution of allostery in the cyclic nucleotide binding module - Kannan, Natarajan; Wu, Jian; Anand, Ganesh S; Yooseph, Shibu; Neuwald, Andrew F; Venter, J Craig; Taylor, Susan S
Analysis of cyclic nucleotide binding (CNB) domains shows that they have evolved to sense a wide variety of second messenger signals; a mechanism for allosteric regulation by CNB domains is proposed.
121.
