PubMed Central (PMC3 - NLM DTD)
(2,081,148 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
Mostrando recursos 141 - 160 de 3,096
141.
Quantification of global transcription patterns in prokaryotes using spotted microarrays - Sidders, Ben; Withers, Mike; Kendall, Sharon L; Bacon, Joanna; Waddell, Simon J; Hinds, Jason; Golby, Paul; Movahedzadeh, Farahnaz; Cox, Robert A; Frita, Rosangela; ten Bokum, Annemieke MC; Wernisch, Lorenz; Stoker, Neil G
An analysis is described, applicable to any spotted microarray dataset that is produced using genomic DNA as a reference for quantifying prokaryotic levels of mRNA on a genome-wide scale.
142.
Direct selection and phage display of a Gram-positive secretome - Jankovic, Dragana; Collett, Michael A; Lubbers, Mark W; Rakonjac, Jasna
A phage display system for direct selection, identification, expression and purification of bacterial secretome proteins has been developed.
144.
Post-translational modifications of histones H3 and H4 associated with the histone methyltransferases Suv39h1 and G9a - Robin, Philippe; Fritsch, Lauriane; Philipot, Ophélie; Svinarchuk, Fedor; Ait-Si-Ali, Slimane
Mass spectrometry analysis of the post-transcriptional modifications of histones H3 and H4 that were co-purified with histone methyltransferases Suv39h1 and G9a shows that, in HeLa cells, histone methyltransferases can be physically associated with acetylated histones, which normally mark transcriptionally active chromatin.
146.
Medicine man - Petsko, Gregory A
It becomes imperative that our doctors bring to the practice of medicine a true scientific perspective; it may be just as important that those of us doing biomedical research try to learn more of what doctors know.
149.
Tipping the balance in autoimmune disease - Collins, Mary
A report on the FASEB Summer Research Conference on Autoimmunity, Saxtons River, USA, 14-29 July 2007.
150.
A cornucopia of delights for the mouse fancier - Norris, Dominic P; Nowotschin, Sonja; Hadjantonakis, Anna-Katerina
A report on the Mouse Molecular Genetics meeting, Hinxton, UK, 5-9 September 2007.
152.
Finding disease candidate genes by liquid association - Li, Ker-Chau; Palotie, Aarno; Yuan, Shinsheng; Bronnikov, Denis; Chen, Daniel; Wei, Xuelian; Choi, Oi-Wa; Saarela, Janna; Peltonen, Leena
A novel approach to finding candidate genes by using gene-expression data has been developed and used to identify a multiple sclerosis susceptibility candidate genes.
153.
A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans - Gomes, Ana C; Miranda, Isabel; Silva, Raquel M; Moura, Gabriela R; Thomas, Benjamin; Akoulitchev, Alexandre; Santos, Manuel AS
An unusual decoding of leucine CUG codons as serine in Candida albicans revealed unanticipated codon ambiguity, which expands the proteome of this human pathogen exponentially.
154.
PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation - Portales-Casamar, Elodie; Kirov, Stefan; Lim, Jonathan; Lithwick, Stuart; Swanson, Magdalena I; Ticoll, Amy; Snoddy, Jay; Wasserman, Wyeth W
PAZAR is an open-access and open-source database of transcription factor and regulatory sequence annotation with associated web interface and programming tools for data submission and extraction.
156.
Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines - Elling, Axel A; Mitreva, Makedonka; Recknor, Justin; Gai, Xiaowu; Martin, John; Maier, Thomas R; McDermott, Jeffrey P; Hewezi, Tarek; McK Bird, David; Davis, Eric L; Hussey, Richard S; Nettleton, Dan; McCarter, James P; Baum, Thomas J
The generation and analysis of over 20,000 ESTs allowed the identification and expression profiling of 6,860 predicted genes in the nematode Heterodera glycines. This revealed that gene expression patterns in the dauer stage of Caenorhabditis elegans are not conserved in H. glycines.
158.
Transcriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and disease - Vanpoucke, Griet; Orr, Brigid; Grace, O Cathal; Chan, Ray; Ashley, George R; Williams, Karin; Franco, Omar E; Hayward, Simon W; Thomson, Axel A
Comparison of SAGE libraries for prostatic inductive mesenchyme and the complete prostatic rudiment revealed 219 transcripts that were enriched in, or specific to, inductive mesenchyme. Further analysis suggested that Scube1 is a novel stromal molecule involved in prostate development and tumorigenesis.
159.
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype - Blenkiron, Cherie; Goldstein, Leonard D; Thorne, Natalie P; Spiteri, Inmaculada; Chin, Suet-Feung; Dunning, Mark J; Barbosa-Morais, Nuno L; Teschendorff, Andrew E; Green, Andrew R; Ellis, Ian O; Tavaré, Simon; Caldas, Carlos; Miska, Eric A
Integrated analysis of miRNA expression and genomic changes in human breast tumors allows the classification of tumor subtypes.
160.
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer - Chin, Suet F; Teschendorff, Andrew E; Marioni, John C; Wang, Yanzhong; Barbosa-Morais, Nuno L; Thorne, Natalie P; Costa, Jose L; Pinder, Sarah E; van de Wiel, Mark A; Green, Andrew R; Ellis, Ian O; Porter, Peggy L; Tavaré, Simon; Brenton, James D; Ylstra, Bauke; Caldas, Carlos
High resolution array-CGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer, and provides a genome-wide list of common copy number alterations associated with aberrant expression and poor prognosis.
141.
