PubMed Central (PMC3 - NLM DTD)
(2,081,148 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).
142.
New research models and novel signal analysis in studies on preterm labor: a key to progress? - Pierzynski, Piotr; Oczeretko, Edward; Laudanski, Piotr; Laudanski, Tadeusz
Preterm labor affects up to 20% of pregnancies, is considered a main cause of associated neonatal morbidity and mortality and is responsible for neonatal care costs of multimillion euros. In spite of that, the commercial market for this clinical indication is rather limited, which may be also related to high liability. Consequently, with only a few exceptions, preterm labor is not in the orbit of great interest of the pharmaceutical industry. Coordinated effort of research community may bring the change and help required to reduce the influence of this multifactorial syndrome on society. Between the novel techniques that are being...
143.
Inflammatory pathways in the mechanism of parturition - Norman, Jane E; Bollapragada, Shrikant; Yuan, Mei; Nelson, Scott M
Increasing evidence suggests that parturition is an inflammatory process. In this brief overview, inflammatory events occurring in association with parturition, and the mechanism by which they may contribute to labour and delivery will be discussed. Mention will be made of how this information may be of use in regulating the timing and the onset of parturition.
144.
A translational approach to studying preterm labour - Tribe, Rachel Marie
Preterm labour continues to be a major contributor to neonatal and infant morbidity. Recent data from the USA indicate that the number of preterm deliveries (including those associated with preterm labour) has risen in the last 20 years by 30%. This increase is despite considerable efforts to introduce new therapies for the prevention and treatment of preterm labour and highlights the need to assess research in this area from a fresh perspective. In this paper we discuss i) the limitations of our knowledge concerning prediction, prevention and treatment of preterm labour and ii) future multidisciplinary strategies for improving our approach.
145.
Reductionist and system approaches to study the role of infection in preterm labor and delivery - Laudanski, Piotr; Pierzynski, Piotr; Laudanski, Tadeusz
A substantial number of patients with preterm labor and delivery do not show clinical signs of infection, however, it is the subclinical form which is the main causative factor and often results in premature delivery. The hitherto commonly applied methods of inflammation detection are based either on potentially hazardous amniocentesis or still insufficient inflammation-related protein measurement in the serum or other biological fluids.
147.
Progesterone for the prevention of preterm birth in women with multiple pregnancies: the AMPHIA trial - Lim, Arianne C; Bloemenkamp, Kitty WM; Boer, Kees; Duvekot, Johannes J; Erwich, Jan Jaap HM; Hasaart, Tom HM; Hummel, Pieter; Mol, Ben WJ; Offermans, Jos PM; van Oirschot, Charlotte M; Santema, Job G; Scheepers, Hubertina CJ; Schöls, Willem A; Vandenbussche, Frank PHA; Wouters, Maurice GAJ; Bruinse, Hein W;
148.
Disproportionate Intrauterine Growth Intervention Trial At Term: DIGITAT - Boers, Kim E; Bijlenga, Denise; Mol, Ben WJ; LeCessie, Saskia; Birnie, Erwin; van Pampus, Marielle G; Stigter, Rob H; Bloemenkamp, Kitty WM; van Meir, Claudia A; van der Post, Joris AM; Bekedam, Dick J; Ribbert, Lucy SM; Drogtrop, Addie P; van der Salm, Paulien CM; Huisjes, Anjoke JM; Willekes, Christine; Roumen, Frans JME; Scheepers, Hubertina CJ; de Boer, Karin; Duvekot, Johannes J; Thornton, Jim G; Scherjon, Sicco A
152.
Induction of labour versus expectant monitoring in women with pregnancy induced hypertension or mild preeclampsia at term: the HYPITAT trial - Koopmans, Corine M; Bijlenga, Denise; Aarnoudse, Jan G; van Beek, Erik; Bekedam, Dick J; van den Berg, Paul P; Burggraaff, Jan M; Birnie, Erwin; Bloemenkamp, Kitty WM; Drogtrop, Addi P; Franx, Arie; de Groot, Christianne JM; Huisjes, Anjoke JM; Kwee, Anneke; le Cessie, Saskia; van Loon, Aren J; Mol, Ben WJ; van der Post, Joris AM; Roumen, Frans JME; Scheepers, Hubertina CJ; Spaanderman, Marc EA; Stigter, Rob H; Willekes, Christine; van Pampus, Maria G
141.
