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PubMed Central (PMC3 - NLM DTD) (2,891,295 recursos)
Archive of life sciences journal literature at the U.S. National Institutes of Health (NIH), developed and managed by NIH's National Center for Biotechnology Information (NCBI) in the National Library of Medicine (NLM).

Antioxidants & Redox Signaling

Mostrando recursos 1 - 20 de 921

1. Angiotensin-Converting Enzyme Inhibitor Captopril Reverses the Adverse Cardiovascular Effects of Polymerized Hemoglobin - Li, Tao; Zhou, Ronghua; Yao, Yusheng; Yang, Qian; Zhou, Cheng; Wu, Wei; Li, Qian; You, Zhen; Zhao, Xiaolin; Yang, Linhui; Li, Chen; Zhu, Da; Qiu, Yanhua; Luo, Ming; Tan, Zhaoxia; Li, Huan; Chen, Yanfang; Gong, Gu; Feng, Yuan; Dian, Ke; Liu, Jin

2. MicroRNA-126 Suppresses Mesothelioma Malignancy by Targeting IRS1 and Interfering with the Mitochondrial Function - Tomasetti, Marco; Nocchi, Linda; Staffolani, Sara; Manzella, Nicola; Amati, Monica; Goodwin, Jacob; Kluckova, Katarina; Nguyen, Maria; Strafella, Elisabetta; Bajzikova, Martina; Peterka, Martin; Lettlova, Sandra; Truksa, Jaroslav; Lee, Wan; Dong, Lan-Feng; Santarelli, Lory; Neuzil, Jiri

3. RORα Decreases Oxidative Stress Through the Induction of SOD2 and GPx1 Expression and Thereby Protects Against Nonalcoholic Steatohepatitis in Mice - Han, Yong-Hyun; Kim, Hyeon-Ji; Kim, Eun-Jin; Kim, Kyu-Seo; Hong, Suckchang; Park, Hyeung-Geun; Lee, Mi-Ock

4. Aldosterone Activates Transcription Factor Nrf2 in Kidney Cells Both In Vitro and In Vivo - Queisser, Nina; Oteiza, Patricia I.; Link, Samuel; Hey, Valentin; Stopper, Helga; Schupp, Nicole

5. May the Thyroid Gland and Thyroperoxidase Participate in Nitrosylation of Serum Proteins and Sporadic Parkinson's Disease? - Fernández, Emilio; García-Moreno, José-Manuel; Martín de Pablos, Angel; Chacón, José

6. Abnormal Ca2+ Cycling in Failing Ventricular Myocytes: Role of NOS1-Mediated Nitroso-Redox Balance - Ziolo, Mark T.; Houser, Steven R.

7. Regenerative Medicine for the Heart: Perspectives on Stem-Cell Therapy - Cho, Gun-Sik; Fernandez, Laviel; Kwon, Chulan

8. Cardiac Stem Cells: Biology and Clinical Applications - Goichberg, Polina; Chang, Jerway; Liao, Ronglih; Leri, Annarosa

9. Citrate Synthase Is a Novel In Vivo Matrix Metalloproteinase-9 Substrate That Regulates Mitochondrial Function in the Postmyocardial Infarction Left Ventricle - de Castro Brás, Lisandra E.; Cates, Courtney A.; DeLeon-Pennell, Kristine Y.; Ma, Yonggang; Iyer, Rugmani Padmanabhan; Halade, Ganesh V.; Yabluchanskiy, Andriy; Fields, Gregg B.; Weintraub, Susan T.; Lindsey, Merry L.

10. GRK2 in the Heart: A GPCR Kinase and Beyond - Huang, Zheng Maggie; Gao, Erhe; Chuprun, J. Kurt; Koch, Walter J.

11. Mitochondrial Genome Linearization Is a Causative Factor for Cardiomyopathy in Mice and Drosophila - Chen, Yun; Sparks, Megan; Bhandari, Poonam; Matkovich, Scot J.; Dorn, Gerald W.

12. Membrane-Bound CYB5R3 Is a Common Effector of Nutritional and Oxidative Stress Response Through FOXO3a and Nrf2 - Siendones, Emilio; SantaCruz-Calvo, Sara; Martín-Montalvo, Alejandro; Cascajo, María V.; Ariza, Julia; López-Lluch, Guillermo; Villalba, José M.; Acquaviva-Bourdain, Cécile; Roze, Emmanuel; Bernier, Michel; de Cabo, Rafael; Navas, Plácido

13. YCF1-Mediated Cadmium Resistance in Yeast Is Dependent on Copper Metabolism and Antioxidant Enzymes - Wei, Wenzhong; Smith, Nathan; Wu, Xiaobin; Kim, Heejeong; Seravalli, Javier; Khalimonchuk, Oleh; Lee, Jaekwon
Aims: Acquisition and detoxification of metal ions are vital biological processes. Given the requirement of metallochaperones in cellular copper distribution and metallation of cuproproteins, this study investigates whether the metallochaperones also deliver metal ions for transporters functioning in metal detoxification. Results: Resistance to excess cadmium and copper of the yeast Saccharomyces cerevisiae, which is conferred by PCA1 and CaCRP1 metal efflux P-type ATPases, respectively, does not rely on known metallochaperones, Atx1p, Ccs1p, and Cox17p. Copper deficiency induced by the expression of CaCRP1 encoding a copper exporter occurs in the absence of Atx1p. Intriguingly, CCS1 encoding the copper chaperone for superoxide...

14. Oxidant-Induced Activation of cGMP-Dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury - Lorenz, Jana E.; Kallenborn-Gerhardt, Wiebke; Lu, Ruirui; Syhr, Katharina M.J.; Eaton, Philip; Geisslinger, Gerd; Schmidtko, Achim
Aims: Emerging lines of evidence indicate that oxidants such as hydrogen peroxide exert specific signaling functions during the processing of chronic pain. However, the mechanisms by which oxidants regulate pain processing in vivo remain poorly understood. Here, we investigated whether cyclic guanosine monophosphate (cGMP)-dependent protein kinase Iα (cGKIα), which can be activated by oxidants independently of cGMP, serves as a primary redox target during pain processing. Results: After peripheral nerve injury, oxidant-induced cGKIα activation is increased in dorsal root ganglia of mice. Knock-in (KI) mice in which cGKIα cannot transduce oxidant signals demonstrated reduced neuropathic pain behaviors after peripheral nerve...

15. Hypoxamirs and Mitochondrial Metabolism - Cottrill, Katherine A.; Chan, Stephen Y.; Loscalzo, Joseph

16. MicroRNAs in Hypoxia Response - Greco, Simona; Martelli, Fabio

17. Do Fish Oil Omega-3 Fatty Acids Enhance Antioxidant Capacity and Mitochondrial Fatty Acid Oxidation in Human Atrial Myocardium via PPARγ Activation? - Anderson, Ethan J.; Thayne, Kathleen A.; Harris, Mitchel; Shaikh, Saame Raza; Darden, Timothy M.; Lark, Daniel S.; Williams, John Mark; Chitwood, W. Randolph; Kypson, Alan P.; Rodriguez, Evelio

18. Hypoxia-Induced miR-210 Modulates Tissue Response to Acute Peripheral Ischemia - Zaccagnini, Germana; Maimone, Biagina; Di Stefano, Valeria; Fasanaro, Pasquale; Greco, Simona; Perfetti, Alessandra; Capogrossi, Maurizio C.; Gaetano, Carlo; Martelli, Fabio

19. HypoxamiRs and Cancer: From Biology to Targeted Therapy - Gee, Harriet E.; Ivan, Cristina; Calin, George A.; Ivan, Mircea

20. HypoxamiR Regulation and Function in Ischemic Cardiovascular Diseases - Greco, Simona; Gaetano, Carlo; Martelli, Fabio

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