Ventura, F; Antunes, H; Brito, C; Pardal, F; Pereira, T; Vieira, AP
Ventura, F; Gomes, J; Duarte, ML; Fernandes, JC; Brito, C
Ventura, F; Vilarinho, C; Duarte, ML; Pardal, F; Brito, C
Ventura, F; Pereira, T; Duarte, ML; Marques, H; Pardal, F; Brito, C
Indeterminate cell histiocytosis (ICH) is a rare proliferative disorder, in which the predominant cells share morphologic and immunophenotypic features from both Langerhans and non-Langerhans cell histiocytosis. We describe a 62-year-old man presenting a 2-month history of firm nodular lesions on the upper lip. Histopathology, immunohistochemical, and ultrastructural analysis showed typical findings of ICH. The patient was treated with thalidomide and almost complete regression of the lesions was reached within 7 months. Nevertheless, one month after remission, he developed an acute myeloid leukemia of the subtype monocytic leukemia (M5). The patient's condition rapidly worsened and he died due to a respiratory...
Rocha, J; Pereira, T; Sousa-Basto, A; Brito, C
Protein contact dermatitis (PCD) is a contact dermatitis caused by high-molecular-weight proteins. This entity has been reported with increasing frequency, most commonly as occupational hand dermatitis in food handlers. Clinically, it is characterized by a chronic and recurrent dermatitis with erythema, scaling, and fissures with acute exacerbations occurring a few minutes after contact with offending allergen. We report two cases in confectioners who presented with chronic hand dermatitis.
Rocha, J; Ventura, F; Vieira, AP; Pinheiro, AR; Fernandes, F; Brito, C
INTRODUCTION: Alopecia areata usually presents as patchy, nonscarring hair loss. It seems to be an immune mediated disease, whereas genetic predisposition, environmental and psychological triggers may be involved in its aetiology.
OBJECTIVES: To study the epidemiology, clinical aspects, associations, and treatment of alopecia areata in the paediatric population of Peadiatric Dermatology outpatients over a 9-year period. Some psychologic characteristics were also assessed.
METHODS: Descriptive and retrospective study of all newly diagnosed AA cases seen from January 2000 to December 2008 at the Hospital de São Marcos' Paediatric Dermatology Department. Fifteen patients with AA were interviewed for psycologic evaluation.
RESULTS: Forty-eight cases (54% male/46%...